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Lista de obras de Jan Tytgat

268. Biological activities of PnTx2-6, an exciting toxin from spider Phoneutria nigriventer

A 'conovenomic' analysis of the milked venom from the mollusk-hunting cone snail Conus textile--the pharmacological importance of post-translational modifications

artículo científico publicado en 2013

A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins ⬇️

artículo científico publicado en 2018

A Subfamily of Acidic α-K+ Toxins ⬇️

artículo científico publicado el 14 de octubre de 2003

A Venomics approach coupled to high-throughput toxin production strategies identifies the first venom-derived melanocortin receptor agonists

artículo científico publicado en 2020

A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties ⬇️

artículo científico publicado el 6 de abril de 2011

A common "hot spot" confers hERG blockade activity to alpha-scorpion toxins affecting K+ channels.

artículo científico publicado en 2008

A gamut of undiscovered electrophysiological effects produced by Tityus serrulatus toxin 1 on NaV-type isoforms

artículo científico publicado en 2015

A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins

artículo científico publicado en 2012

A neolignan-type impurity arising from the peracid oxidation reaction of anethole in the surreptitious synthesis of 4-methoxyamphetamine (PMA).

artículo científico publicado en 2004

A new Kaliotoxin selective towards Kv1.3 and Kv1.2 but not Kv1.1 channels expressed in oocytes.

artículo científico publicado en 2008

A new multigene HCIQ subfamily from the sea anemone Heteractis crispa encodes Kunitz-peptides exhibiting neuroprotective activity against 6-hydroxydopamine ⬇️

artículo científico publicado en 2020

A novel conotoxin from Conus betulinus, kappa-BtX, unique in cysteine pattern and in function as a specific BK channel modulator

artículo científico publicado en 2003

A novel conotoxin inhibiting vertebrate voltage-sensitive potassium channels

artículo científico publicado en 2003

A novel sea anemone peptide that inhibits acid-sensing ion channels

artículo científico publicado en 2013

A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new alpha-KTX subfamily

artículo científico publicado en 2006

A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors

artículo científico publicado en 2012

A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol

artículo científico publicado en 2009

A potent potassium channel blocker from Mesobuthus eupeus scorpion venom

artículo científico publicado en 2010

APETx4, a Novel Sea Anemone Toxin and a Modulator of the Cancer-Relevant Potassium Channel KV10.1.

artículo científico publicado en 2017

AaHIV a sodium channel scorpion toxin inhibits the proliferation of DU145 prostate cancer cells

scientific article published on 24 October 2019

AbeTx1 Is a Novel Sea Anemone Toxin with a Dual Mechanism of Action on Shaker-Type K⁺ Channels Activation

artículo científico publicado en 2018

Action of clathrodin and analogues on voltage-gated sodium channels

artículo científico publicado en 2014

Active Sites of Spinoxin, a Potassium Channel Scorpion Toxin, Elucidated by Systematic Alanine Scanning

artículo científico publicado en 2016

Adaptive evolution of scorpion sodium channel toxins.

artículo científico publicado en 2004

Ala-7, His-10 and Arg-12 are crucial amino acids for activity of a synthetically engineered μ-conotoxin.

artículo científico publicado en 2013

Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine

scientific article published on 10 October 2016

An allosteric binding site of the α7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine binding protein

artículo científico publicado en 2017

An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.

artículo científico publicado en 2008

An overview of toxins and genes from the venom of the Asian scorpion Buthus martensi Karsch

artículo científico publicado en 2002

An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis.

artículo científico publicado en 2005

Animal peptides targeting voltage-activated sodium channels.

artículo científico publicado en 2008

Anise oil as para-methoxyamphetamine (PMA) precursor

artículo científico publicado en 2003

Antibacterial and antifungal properties of alpha-helical, cationic peptides in the venom of scorpions from southern Africa.

artículo científico publicado en 2002

Antimicrobial peptides from scorpion venom induce Ca2+ signaling in HL-60 cells ⬇️

artículo científico publicado el 7 de noviembre de 2003

Antinociceptive effects of new pyrazoles compounds mediated by the ASIC-1α channel, TRPV-1 and μMOR receptors

scientific article published on 03 May 2019

Antiprotozoan lead discovery by aligning dry and wet screening: prediction, synthesis, and biological assay of novel quinoxalinones.

artículo científico publicado en 2014

Application of the characteristic function to evaluate and compare analytical variability in an external quality assessment scheme for serum ethanol

artículo científico publicado en 2015

Assignment of voltage-gated potassium channel blocking activity to kappa-KTx1.3, a non-toxic homologue of kappa-hefutoxin-1, from Heterometrus spinifer venom.

artículo científico publicado en 2004

Astemizole analogues with reduced hERG inhibition as potent antimalarial compounds.

artículo científico publicado en 2017

Atypical reactive center Kunitz-type inhibitor from the sea anemone Heteractis crispa.

artículo científico publicado en 2012

BcsTx3 is a founder of a novel sea anemone toxin family of potassium channel blocker.

artículo científico publicado en 2013

Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities

artículo científico publicado en 2020

Biochemical and electrophysiological characterization of two sea anemone type 1 potassium toxins from a geographically distant population of Bunodosoma caissarum

artículo científico publicado en 2013

Biochemical characterization of cysteine-rich peptides from Oxyopes sp. venom that block calcium ion channels.

artículo científico publicado en 2008

Biochemical characterization of the venom of Central American scorpion Didymocentrus krausi Francke, 1978 (Diplocentridae) and its toxic effects in vivo and in vitro

article

BjalphaIT: a novel scorpion alpha-toxin selective for insects--unique pharmacological tool

artículo científico publicado en 2005

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

artículo científico publicado en 2013

BmBKTx1, a novel Ca2+-activated K+ channel blocker purified from the Asian scorpion Buthus martensi Karsch.

artículo científico publicado en 2004

BmTx3, a scorpion toxin with two putative functional faces separately active on A-type K+ and HERG currents

artículo científico publicado en 2004

C-Terminal residues in small potassium channel blockers OdK1 and OSK3 from scorpion venom fine-tune the selectivity

artículo científico publicado en 2017

Cardiac channelopathy causing sudden death as revealed by molecular autopsy ⬇️

artículo científico publicado el 28 de febrero de 2012

Caterpillar Venom: A Health Hazard of the 21st Century

scientific article published on 30 May 2020

Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels

artículo científico publicado en 2003

Characterization of Kbot21 Reveals Novel Side Chain Interactions of Scorpion Toxins Inhibiting Voltage-Gated Potassium Channels.

artículo científico publicado en 2015

Characterization of scorpion alpha-like toxin group using two new toxins from the scorpion Leiurus quinquestriatus hebraeus

artículo científico publicado en 2002

Chemical Synthesis, Proper Folding, Nav Channel Selectivity Profile and Analgesic Properties of the Spider Peptide Phlotoxin 1

scientific article published on 21 June 2019

Chronic administration of anticholinergics in rats induces a shift from muscarinic to purinergic transmission in the bladder wall

artículo científico publicado en 2013

Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels

artículo científico publicado en 2017

Conotoxins targeting nicotinic acetylcholine receptors: an overview

artículo científico publicado en 2014

Consequences of Decontamination Procedures in Forensic Hair Analysis Using Metal-Assisted Secondary Ion Mass Spectrometry Analysis

artículo científico publicado en 2016

Corrigendum to "Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK" [Peptides 99 (2018) 169-178].

artículo científico publicado en 2018

Corrigendum to “Jellyfish and other cnidarian envenomations cause pain by affecting TRPV1 channels” [FEBS Lett. 580 (2006) 5728-5732]

artículo científico publicado en 2007

Crotamine pharmacology revisited: novel insights based on the inhibition of KV channels.

artículo científico publicado en 2012

Crystal Structures of a Cysteine-modified Mutant in Loop D of Acetylcholine-binding Protein

artículo científico publicado en 2011

Design and characterization of a novel structural class of Kv1.3 inhibitors

artículo científico publicado en 2020

Design of Bioactive Peptides from Naturally Occurring  -Conotoxin Structures

artículo científico publicado en 2012

Design of sodium channel ligands with defined selectivity - a case study in scorpion alpha-toxins.

artículo científico publicado en 2017

Determination of species-specific components in the venom of Parabuthus scorpions from southern Africa using matrix-assisted laser desorption time-of-flight mass spectrometry

artículo científico publicado en 2002

Development and validation of a fast ionic liquid-based dispersive liquid-liquid microextraction procedure combined with LC-MS/MS analysis for the quantification of benzodiazepines and benzodiazepine-like hypnotics in whole blood.

artículo científico publicado en 2016

Development and validation of a sensitive UPLC-MS/MS method for the analysis of narcotic analgesics in urine and whole blood in forensic context

artículo científico publicado en 2011

Development and validation of a sensitive ultra performance liquid chromatography tandem mass spectrometry method for the analysis of fentanyl and its major metabolite norfentanyl in urine and whole blood in forensic context

artículo científico publicado en 2010

Differential effects of five 'classical' scorpion beta-toxins on rNav1.2a and DmNav1 provide clues on species-selectivity.

artículo científico publicado en 2006

Differential effects of the recombinant toxin PnTx4(5-5) from the spider Phoneutria nigriventer on mammalian and insect sodium channels

artículo científico publicado en 2015

Differential ion current activation by human 5-HT(1A) receptors in Xenopus oocytes: evidence for agonist-directed trafficking of receptor signalling

artículo científico publicado en 2005

Discovery of a new subclass of α-conotoxins in the venom of Conus australis

artículo científico publicado en 2014

Drosotoxin, a selective inhibitor of tetrodotoxin-resistant sodium channels

artículo científico publicado en 2010

Drug- and mutagenesis-induced changes in the selectivity filter of a cardiac two-pore background K+ channel

artículo científico publicado en 2003

Effects of deletion and insertion of amino acids on the activity of HelaTx1, a scorpion toxin on potassium channels

artículo científico publicado en 2015

Electrophysiological characterization of Tityus obscurus β toxin 1 (To1) on Na+-channel isoforms

scientific article published on 14 August 2018

Electrophysiological characterization of Ts6 and Ts7, K⁺ channel toxins isolated through an improved Tityus serrulatus venom purification procedure

artículo científico publicado en 2014

Electrophysiological characterization of the first Tityus serrulatus alpha-like toxin, Ts5: Evidence of a pro-inflammatory toxin on macrophages.

artículo científico publicado en 2015

Evaluation of 11 ionic liquids as potential extraction solvents for benzodiazepines from whole blood using liquid-liquid microextraction combined with LC-MS/MS

artículo científico publicado en 2018

Evaluation of the suitability of ionic liquid-based liquid-liquid microextractions for blood protein removal

artículo científico publicado en 2018

Evidence for a function-specific mutation in the neurotoxin, parabutoxin 3.

artículo científico publicado en 2003

Evolutionary Diversification of Mesobuthus  -Scorpion Toxins Affecting Sodium Channels

artículo científico publicado en 2012

Evolutionary epitopes of Hsp90 and p23: implications for their interaction

artículo científico publicado en 2004

Evolutionary origin of inhibitor cystine knot peptides

artículo científico publicado en 2003

Evolutionary trace analysis of scorpion toxins specific for K-channels

artículo científico publicado en 2004

Expanding the pharmacological profile of κ-hefutoxin 1 and analogues: A focus on the inhibitory effect on the oncogenic channel Kv10.1.

artículo científico publicado en 2016

Experimental conversion of a defensin into a neurotoxin: implications for origin of toxic function

artículo científico publicado en 2014

Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels

artículo científico publicado en 2004

Expression, renaturation and functional analysis of an excitatory insect-specific toxin from scorpion Buthus martensii Karsch

artículo científico publicado en 2005

Fast and easy extraction of antidepressants from whole blood using ionic liquids as extraction solvent.

artículo científico publicado en 2017

First report on BaltCRP, a cysteine-rich secretory protein (CRISP) from Bothrops alternatus venom: Effects on potassium channels and inflammatory processes

artículo científico publicado en 2019

Fluorescent protein-scorpion toxin chimera is a convenient molecular tool for studies of potassium channels

artículo científico publicado en 2016

Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes

artículo científico publicado en 2005

Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana

artículo científico publicado en 2003

Gambierol and n-alkanols inhibit Shaker Kv channel via distinct binding sites outside the K(+) pore.

artículo científico publicado en 2016

Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels.

artículo científico publicado en 2008

Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes

artículo científico publicado en 2018

Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease

artículo científico publicado en 2017

How a Scorpion Toxin Selectively Captures a Prey Sodium Channel: the Molecular and Evolutionary Basis Uncovered

scientific article published on 18 June 2020

Hydrogen peroxide reactions on cocaine in hair using imaging mass spectrometry

artículo científico publicado en 2014

Identification, chemical synthesis, structure, and function of a new KV 1 channel blocking peptide from Oulactis sp

artículo científico publicado en 2018

Immunosuppressive evidence of Tityus serrulatus toxins Ts6 and Ts15: insights of a novel K(+) channel pattern in T cells

artículo científico publicado en 2015

Importance of position 8 in μ-conotoxin KIIIA for voltage-gated sodium channel selectivity

artículo científico publicado en 2011

Importance of the conserved aromatic residues in the scorpion alpha-like toxin BmK M1: the hydrophobic surface region revisited.

artículo científico publicado en 2003

In the picture: disulfide-poor conopeptides, a class of pharmacologically interesting compounds

artículo científico publicado en 2016

Inhibitory effect of the recombinant Phoneutria nigriventer Tx1 toxin on voltage-gated sodium channels.

artículo científico publicado en 2012

Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2

artículo científico publicado en 2009

Investigating possible biological targets of Bj-CRP, the first cysteine-rich secretory protein (CRISP) isolated from Bothrops jararaca snake venom

artículo científico publicado en 2016

Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom

artículo científico publicado en 2012

Ionic Liquid-Based Liquid-Liquid Microextraction for Benzodiazepine Analysis in Postmortem Blood Samples

artículo científico publicado en 2018

Isolation and characterization of Ts19 Fragment II, a new long-chain potassium channel toxin from Tityus serrulatus venom

artículo científico publicado en 2015

Isolation and characterization of two novel scorpion toxins: The alpha-toxin-like CeII8, specific for Na(v)1.7 channels and the classical anti-mammalian CeII9, specific for Na(v)1.4 channels.

artículo científico publicado en 2010

Jaburetox, a natural insecticide derived from Jack Bean Urease, activates voltage-gated sodium channels to modulate insect behavior

artículo científico publicado en 2018

Jellyfish and other cnidarian envenomations cause pain by affecting TRPV1 channels

artículo científico publicado en 2006

Jingzhaotoxin-I, a novel spider neurotoxin preferentially inhibiting cardiac sodium channel inactivation

artículo científico publicado en 2004

KV1.2 channel-specific blocker from Mesobuthus eupeus scorpion venom: Structural basis of selectivity

artículo científico publicado en 2018

Kbot55, purified from Buthus occitanus tunetanus venom, represents the first member of a novel α-KTx subfamily

artículo científico publicado en 2015

Kunitz-Type Peptide HCRG21 from the Sea Anemone Heteractis crispa Is a Full Antagonist of the TRPV1 Receptor

artículo científico publicado en 2016

Ligand- and structure-based virtual screening for clathrodin-derived human voltage-gated sodium channel modulators

artículo científico publicado en 2013

Macrophage alteration induced by inflammatory toxins isolated from Tityus discrepans scorpion venom. The role of Na(+)/Ca(2+) exchangers

artículo científico publicado en 2014

Magnificamide, a β-Defensin-Like Peptide from the Mucus of the Sea Anemone Heteractis magnifica, Is a Strong Inhibitor of Mammalian α-Amylases

scientific article published on 21 September 2019

Medical Findings and Toxicological Analysis in Infant Death by Balloon Gas Asphyxia: A Case Report

artículo científico publicado en 2017

MeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity

artículo científico publicado en 2010

Modular organization of α-toxins from scorpion venom mirrors domain structure of their targets, sodium channels.

artículo científico publicado en 2013

Modulation of voltage-gated Na+ and K+ channels by pumiliotoxin 251D: a "joint venture" alkaloid from arthropods and amphibians

artículo científico publicado en 2008

Molecular basis of the mammalian potency of the scorpion alpha-like toxin, BmK M1.

artículo científico publicado en 2005

Molecular divergence of two orthologous scorpion toxins affecting potassium channels.

artículo científico publicado en 2011

Molecular diversity and functional evolution of scorpion potassium channel toxins

artículo científico publicado en 2010

Molecular diversity of the telson and venom components from Pandinus cavimanus (Scorpionidae Latreille 1802): transcriptome, venomics and function.

artículo científico publicado en 2012

Multiple actions of phi-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins

artículo científico publicado en 2013

Multisite Binding of a General Anesthetic to the Prokaryotic Pentameric Erwinia chrysanthemi Ligand-gated Ion Channel (ELIC)

artículo científico publicado en 2013

Neurotoxin Merging: A Strategy Deployed by the Venom of the Spider Cupiennius salei to Potentiate Toxicity on Insects

artículo científico publicado en 2020

Neurotoxins and Their Binding Areas on Voltage-Gated Sodium Channels ⬇️

artículo científico publicado el 9 de noviembre de 2011

New "Birtoxin analogs" from Androctonus australis venom

artículo científico publicado en 2005

New Insights into the Type II Toxins from the Sea Anemone Heteractis crispa

scientific article published on 10 January 2020

Non-disulfide-bridged peptides from Tityus serrulatus venom: Evidence for proline-free ACE-inhibitors

artículo científico publicado en 2016

Novel Conopeptides of Largely Unexplored Indo Pacific Conus sp.

artículo científico publicado en 2016

Novel conopeptides of the I-superfamily occur in several clades of cone snails

artículo científico publicado en 2004

Novel potassium channel blocker venom peptides from Mesobuthus gibbosus (Scorpiones: Buthidae).

artículo científico publicado en 2012

OD1, the first toxin isolated from the venom of the scorpion Odonthobuthus doriae active on voltage-gated Na+ channels

artículo científico publicado en 2005

OdK2, a Kv1.3 channel-selective toxin from the venom of the Iranian scorpion Odonthobuthus doriae.

artículo científico publicado en 2008

Oleamide in Ipomoea and Dillenia species and inflammatory activity investigated through ion channel inhibition

artículo científico publicado en 2020

PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold

article

Panusin represents a new family of β-defensin-like peptides in invertebrates

artículo científico publicado en 2016

Partial transcriptomic profiling of toxins from the venom gland of the scorpion Parabuthus stridulus.

artículo científico publicado en 2014

Pc16a, the first characterized peptide from Conus pictus venom, shows a novel disulfide connectivity

artículo científico publicado en 2012

Peptide ion channel toxins from the bootlace worm, the longest animal on Earth

artículo científico publicado en 2018

Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus

artículo científico publicado en 2004

Pharmacological activity and NMR solution structure of the leech peptide HSTX-I

artículo científico publicado en 2020

Pharmacological comparison of two different insect models using the scorpion alpha-like toxin BmK M1 from Buthus martensii Karsch.

artículo científico publicado en 2005

PhcrTx2, a New Crab-Paralyzing Peptide Toxin from the Sea Anemone Phymanthus crucifer.

artículo científico publicado en 2018

Phoneutria nigriventer venom: A pharmacological treasure

artículo científico publicado en 2018

Phyla- and Subtype-Selectivity of CgNa, a Na Channel Toxin from the Venom of the Giant Caribbean Sea Anemone Condylactis Gigantea

artículo científico publicado en 2010

Potent modulation of the voltage-gated sodium channel Nav1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae.

artículo científico publicado en 2006

Preparation of longitudinal sections of hair samples for the analysis of cocaine by MALDI-MS/MS and TOF-SIMS imaging.

artículo científico publicado en 2015

Protein surface topography as a tool to enhance the selective activity of a potassium channel blocker

scientific article published on 18 September 2019

Purification and biochemical characterization of VesT1s, a novel phospholipase A1 isoform isolated from the venom of the greater banded wasp Vespa tropica

artículo científico publicado en 2018

Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom

artículo científico publicado en 2002

Purification, molecular cloning and functional characterization of HelaTx1 (Heterometrus laoticus): the first member of a new κ-KTX subfamily

artículo científico publicado en 2012

Refined structure of BeM9 reveals arginine hand, an overlooked structural motif in scorpion toxins affecting sodium channels

artículo científico publicado en 2018

Revealing the Function and the Structural Model of Ts4: Insights into the "Non-Toxic" Toxin from Tityus serrulatus Venom

artículo científico publicado en 2015

Role of individual disulfide bridges in the conformation and activity of spinoxin (α-KTx6.13), a potassium channel toxin from Heterometrus spinifer scorpion venom

artículo científico publicado en 2016

Sea anemone venom as a source of insecticidal peptides acting on voltage-gated Na+ channels.

artículo científico publicado en 2006

Serine 329 of the mu-opioid receptor interacts differently with agonists

artículo científico publicado en 2003

Serrumab: a novel human single chain-fragment antibody with multiple scorpion toxin-neutralizing capacities

artículo científico publicado en 2013

Solution structure and alanine scan of a spider toxin that affects the activation of mammalian voltage-gated sodium channels

artículo científico publicado en 2007

Solution structure and functional analysis of HelaTx1: the first toxin member of the к-KTx5 subfamily

scientific article published on 16 March 2020

Spider Toxin PnTx2-1 (δ-Ctenitoxin-Pn1a) Is a Modulator of Sodium Channel Gating

artículo científico publicado en 2018

Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity

artículo científico publicado en 2017

Structural Similarity between Defense Peptide from Wheat and Scorpion Neurotoxin Permits Rational Functional Design

artículo científico publicado en 2014

Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins

artículo científico publicado en 2016

Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa

artículo científico publicado en 2019

Structural basis for the voltage-gated Na+ channel selectivity of the scorpion alpha-like toxin BmK M1.

artículo científico publicado en 2005

Structure of membrane-active toxin from crab spider Heriaeus melloteei suggests parallel evolution of sodium channel gating modifiers in Araneomorphae and Mygalomorphae

artículo científico publicado en 2014

Structure of the SthK carboxy-terminal region reveals a gating mechanism for cyclic nucleotide-modulated ion channels

artículo científico publicado en 2015

Structure, folding and stability of a minimal homologue from Anemonia sulcata of the sea anemone potassium channel blocker ShK.

artículo científico publicado en 2017

Structure-Function Elucidation of a New  -Conotoxin, Lo1a, from Conus longurionis

artículo científico publicado en 2014

Structure-Function Elucidation of a New α-Conotoxin, MilIA, from Conus milneedwardsi

scientific article published on 16 September 2019

Structure-function study of a chlorotoxin-chimer and its activity on Kv1.3 channels

artículo científico publicado en 2004

Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators

artículo científico publicado en 2014

Subtype Specificity of β-Toxin Tf1a from in Voltage Gated Sodium Channels

artículo científico publicado en 2018

Subtype specificity interaction of bactridines with mammalian, insect and bacterial sodium channels under voltage clamp conditions

artículo científico publicado en 2012

Synthesis and characterization of amino acid deletion analogs of κ-hefutoxin 1, a scorpion toxin on potassium channels ⬇️

artículo científico publicado el 29 de mayo de 2013

Synthesis and electrophysiological characterization of cyclic morphiceptin analogues

artículo científico publicado en 2004

Synthesis of novel purpurealidin analogs and evaluation of their effect on the cancer-relevant potassium channel KV10.1.

artículo científico publicado en 2017

Synthesis, folding, structure and activity of a predicted peptide from the sea anemone Oulactis sp. with an ShKT fold

artículo científico publicado en 2018

Synthesis, solution structure, and phylum selectivity of a spider delta-toxin that slows inactivation of specific voltage-gated sodium channel subtypes

artículo científico publicado en 2009

TRPV1 Channel as New Target for Marine Toxins: Example of Gigantoxin I, a Sea Anemone Toxin Acting Via Modulation of the PLA2 Pathway

artículo científico publicado en 2011

TRPV1 as a key determinant in ciguatera and neurotoxic shellfish poisoning

artículo científico publicado en 2007

Target-Driven Positive Selection at Hot Spots of Scorpion Toxins Uncovers Their Potential in Design of Insecticides

artículo científico publicado en 2016

The Birth and Death of Toxins with Distinct Functions: A Case Study in the Sea Anemone Nematostella

artículo científico publicado en 2019

The Health Risks of Belgian Illicit Indoor Cannabis Plantations.

artículo científico publicado en 2018

The Kunitz-Type Protein ShPI-1 Inhibits Serine Proteases and Voltage-Gated Potassium Channels

artículo científico publicado en 2016

The Mediterranean scorpion Mesobuthus gibbosus (Scorpiones, Buthidae): transcriptome analysis and organization of the genome encoding chlorotoxin-like peptides

artículo científico publicado en 2014

The Peptide PnPP-19, a Spider Toxin Derivative, Activates μ-Opioid Receptors and Modulates Calcium Channels.

artículo científico publicado en 2018

The antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels.

artículo científico publicado en 2016

The depressant scorpion neurotoxin LqqIT2 selectively modulates the insect voltage-gated sodium channel

artículo científico publicado en 2005

The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control

artículo científico publicado en 2006

The evaluation of the applicability of a high pH mobile phase in ultrahigh performance liquid chromatography tandem mass spectrometry analysis of benzodiazepines and benzodiazepine-like hypnotics in urine and blood

artículo científico publicado en 2012

The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae

artículo científico publicado en 2006

The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state ⬇️

artículo científico publicado el 11 de febrero de 2013

The new kappa-KTx 2.5 from the scorpion Opisthacanthus cayaporum

artículo científico publicado en 2011

The poison Dart frog's batrachotoxin modulates Nav1.8.

artículo científico publicado en 2004

The proteomic profile of Stichodactyla duerdeni secretion reveals the presence of a novel O-linked glycopeptide

artículo científico publicado en 2013

The sea anemone Bunodosoma granulifera contains surprisingly efficacious and potent insect-selective toxins.

artículo científico publicado en 2002

The use of pesticides in Belgian illicit indoor cannabis plantations.

artículo científico publicado en 2017

Toxin bioportides: exploring toxin biological activity and multifunctionality

artículo científico publicado en 2016

Toxins and potassium channels

artículo científico publicado en 2004

Toxins in Drug Discovery and Pharmacology

artículo científico publicado en 2018

Trancriptomic approach reveals the molecular diversity of Hottentotta conspersus (Buthidae) venom

artículo científico publicado en 2015

Transgenerational epigenetic effects from male exposure to endocrine-disrupting compounds: a systematic review on research in mammals

scientific article published on 12 May 2020

Ts8 scorpion toxin inhibits the Kv4.2 channel and produces nociception in vivo

artículo científico publicado en 2016

Turret and pore block of K+ channels: what is the difference?

artículo científico publicado en 2003

Two new scorpion toxins that target voltage-gated Ca2+ and Na+ channels

artículo científico publicado en 2002

Two novel sodium channel inhibitors from Heriaeus melloteei spider venom differentially interacting with mammalian channel's isoforms

artículo científico publicado en 2008

Two recombinant depressant scorpion neurotoxins differentially affecting mammalian sodium channels

artículo científico publicado en 2010

Two recombinant α-like scorpion toxins from Mesobuthus eupeus with differential affinity toward insect and mammalian Na+ channels ⬇️

artículo científico publicado el 4 de junio de 2013

Unique bell-shaped voltage-dependent modulation of Na+ channel gating by novel insect-selective toxins from the spider Agelena orientalis

artículo científico publicado en 2010

Unraveling the peptidome of the South African cone snails Conus pictus and Conus natalis

artículo científico publicado en 2012

Variability of Potassium Channel Blockers in Mesobuthus eupeus Scorpion Venom with Focus on Kv1.1: AN INTEGRATED TRANSCRIPTOMIC AND PROTEOMIC STUDY.

artículo científico publicado en 2015

Venom characterization of the bark scorpion Centruroides edwardsii (Gervais 1843): Composition, biochemical activities and in vivo toxicity for potential prey

scientific article published on 01 October 2019

Venom components from Citharischius crawshayi spider (Family Theraphosidae): exploring transcriptome, venomics, and function.

artículo científico publicado en 2010

Venomous secretions from marine snails of the Terebridae family target acetylcholine receptors

artículo científico publicado en 2013

Voltage-gated sodium channel isoform-specific effects of pompilidotoxins.

artículo científico publicado en 2010

Voltage-gated sodium channel modulation by scorpion alpha-toxins

artículo científico publicado en 2006

Voltage-sensor conformation shapes the intra-membrane drug binding site that determines gambierol affinity in Kv channels.

artículo científico publicado en 2016

Where cone snails and spiders meet: design of small cyclic sodium-channel inhibitors

artículo científico publicado en 2018

kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity

artículo científico publicado en 2002

t-boc synthesis of huwentoxin-i through native chemical ligation incorporating a trifluoromethanesulfonic acid cleavage strategy

artículo científico publicado en 2016

δ-Conotoxins synthesized using an acid-cleavable solubility tag approach reveal key structural determinants for NaV subtype selectivity.

artículo científico publicado en 2014

PnPP-19, un péptido sintético y no tóxico diseñado a partir de una toxina nigriventer de Phoneutria, potencia la función eréctil a través de NO / cGMP.

artículo científico publicado en 2015

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