Lista de obras -

A Mn(II)-Mn(II) center in human prolidase.

artículo científico publicado en 2012

A double arene hydroxylation mediated by dicopper(II)-hydroperoxide species

artículo científico publicado en 2003

A new CuZ active form in the catalytic reduction of N(2)O by nitrous oxide reductase from Pseudomonas nautica.

artículo científico publicado en 2010

A new dinuclear heme-copper complex derived from functionalized protoporphyrin IX.

artículo científico publicado en 2007

Asymmetric oxidation of sulphides to sulphoxides catalysed by titanium complexes of N-salicylidene-L-amino acids

scholarly article by Stefano Colonna et al published 1987 in Journal of the Chemical Society. Perkin transactions 1

Axial Imidazole Distortion Effects on the Catalytic and Binding Properties of Chelated Deuterohemin Complexes

artículo científico publicado en 1996

Biomimetic Modelling of Copper Enzymes: Synthesis, Characterization, EPR Analysis and Enantioselective Catalytic Oxidations by a New Chiral Trinuclear Copper(II) Complex

article

Catalytic activity, stability, unfolding, and degradation pathways of engineered and reconstituted myoglobins

artículo científico publicado en 2004

Catalytic peroxidation of nitrogen monoxide and peroxynitrite by globins

scientific article published on 01 January 2009

Characterization and peroxidase activity of a myoglobin mutant containing a distal arginine

artículo científico publicado en 2002

Coordination and redox properties of copper interaction with α-synuclein.

artículo científico publicado en 2016

Copper(I) Forms a Redox-Stable 1:2 Complex with α-Synuclein N-Terminal Peptide in a Membrane-Like Environment.

artículo científico publicado en 2016

Copper(I)-α-Synuclein Interaction: Structural Description of Two Independent and Competing Metal Binding Sites

artículo científico publicado en 2013

Copper(I/II), α/β-Synuclein and Amyloid-β: Menage à Trois?

artículo científico publicado en 2015

Copper-Aβ Peptides and Oxidation of Catecholic Substrates: Reactivity and Endogenous Peptide Damage.

artículo científico publicado en 2016

Correction to Aminomethylene-Phosphonate Analogue as a Cu(II) Chelator: Characterization and Application as an Inhibitor of Oxidation Induced by Cu(II)-Prion Peptide Complex

scientific article published on 03 September 2019

Differences in the binding of copper(I) to α- and β-synuclein

scientific journal article

Dopamin, oxidativer Stress und Protein‐Chinonmodifikationen bei Parkinson und anderen neurodegenerativen Erkrankungen

artículo científico publicado en 2019

Easy oxidation and nitration of human myoglobin by nitrite and hydrogen peroxide

artículo científico publicado en 2006

Effect of strain in the proximal ligand on the binding of nitric oxide and carbon monoxide to chelated protoheme complexes

scientific article published on 11 September 2007

Electron transfer complex between nitrous oxide reductase and cytochrome c552 from Pseudomonas nautica: kinetic, nuclear magnetic resonance, and docking studies

artículo científico publicado en 2008

Endogenous arene hydroxylation promoted by copper(I) cluster helicates

artículo científico publicado en 2010

Engineering peroxidase activity in myoglobin: the haem cavity structure and peroxide activation in the T67R/S92D mutant and its derivative reconstituted with protohaemin-l-histidine ⬇️

artículo científico publicado el 1 de febrero de 2004

Formation of reactive nitrogen species at biologic heme centers: a potential mechanism of nitric oxide-dependent toxicity

artículo científico publicado en 2002

Heme binding induces dimerization and nitration of truncated β-amyloid peptide Aβ16 under oxidative stress.

artículo científico publicado en 2013

Hydroxylation of phenolic compounds by a peroxodicopper(II) complex: further insight into the mechanism of tyrosinase

artículo científico publicado en 2005

Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis

scientific article published on 15 June 2011

Inhibitor binding studies on ascorbate oxidase ⬇️

scholarly article

Interaction between Hemin and Prion Peptides: Binding, Oxidative Reactivity and Aggregation

artículo científico publicado en 2020

Interaction of Neuromelanin with Xenobiotics and Consequences for Neurodegeneration; Promising Experimental Models

Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease

artículo científico publicado en 2015

Investigation of Streptomyces antibioticus tyrosinase reactivity toward chlorophenols

artículo científico publicado en 2011

Investigation of azide binding to oxidized type 2 copper depleted ascorbate oxidase from Cucurbita pepo ⬇️

artículo científico publicado en 1989

Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue

artículo científico publicado en 2013

Kinetics and Thermodynamics of Halide and Nitrite Oxidation by Mammalian Heme Peroxidases

Ligand Binding, Conformational and Spectroscopic Properties, and Biomimetic Monooxygenase Activity by the Trinuclear Copper–PHI Complex Derived fromL-Histidine

Mechanistic insight into the activity of tyrosinase from variable-temperature studies in an aqueous/organic solvent

artículo científico publicado en 2006

Mechanistic insight into the catechol oxidase activity by a biomimetic dinuclear copper complex

artículo científico publicado en 2004

Mechanistic insight into the peroxidase catalyzed nitration of tyrosine derivatives by nitrite and hydrogen peroxide

artículo científico publicado en 2004

Metmyoglobin-catalyzed exogenous and endogenous tyrosine nitration by nitrite and hydrogen peroxide

artículo científico publicado en 2004

Modified microperoxidases exhibit different reactivity towards phenolic substrates

artículo científico publicado en 2004

Modular syntheses of multidentate ligands with variable N-donors: applications to tri- and tetracopper(I) complexes

artículo científico publicado en 2007

Myoglobin modification by enzyme-generated dopamine reactive species

artículo científico publicado en 2008

Neuroglobin modification by reactive quinone species

artículo científico publicado en 2013

Neuromelanin can protect against iron-mediated oxidative damage in system modeling iron overload of brain aging and Parkinson's disease

artículo científico publicado en 2008

Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson's disease

artículo científico publicado en 2018

Neuromelanin of the human substantia nigra: an update

artículo científico

Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson's disease.

artículo científico publicado en 2018

Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role

New aspects of the reactivity of tyrosinase

artículo científico publicado en 2004

Nickel binding to histone H4.

artículo científico publicado en 2009

Nitric oxide releasing metal-diazeniumdiolate complexes strongly induce vasorelaxation and endothelial cell proliferation

artículo científico publicado en 2008

Oxidase Reactivity of CuII Bound to N-Truncated Aβ Peptides Promoted by Dopamine ⬇️

artículo científico

Peroxidase catalyzed nitration of tryptophan derivatives. Mechanism, products and comparison with chemical nitrating agents

artículo científico publicado en 2004

Probing the location of the substrate binding site of ascorbate oxidase near type 1 copper: an investigation through spectroscopic, inhibition and docking studies

artículo científico publicado en 2004

Protein self-modification by heme-generated reactive species

artículo científico publicado en 2008

Reactivity and endogenous modification by nitrite and hydrogen peroxide: does human neuroglobin act only as a scavenger?

artículo científico publicado en 2007

Reactivity of copper-α-synuclein peptide complexes relevant to Parkinson's disease.

artículo científico publicado en 2015

Reactivity study on microperoxidase-8 ⬇️

artículo científico publicado el 9 de julio de 2003

Redox reactivity of the heme Fe3+/Fe 2+ couple in native myoglobins and mutants with peroxidase-like activity

artículo científico publicado en 2007

Remote His50 Acts as a Coordination Switch in the High-Affinity N-Terminal Centered Copper(II) Site of α-Synuclein.

artículo científico publicado en 2015

Ruthenium anticancer drugs and proteins: a study of the interactions of the ruthenium(III) complex imidazolium trans-[tetrachloro(dimethyl sulfoxide)(imidazole)ruthenate(III)] with hen egg white lysozyme and horse heart cytochrome c

scholarly article by Angela Casini et al published 7 August 2007 in Journal of Biological Inorganic Chemistry

Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE.

artículo científico publicado en 2016

Synthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis ⬇️

artículo científico publicado el 31 de octubre de 2012

Synthesis, Structure, and Reactivity of Model Complexes of Copper Nitrite Reductase ⬇️

artículo científico publicado el 28 de febrero de 1996

Synthesis, characterization and catalytic oxidations of oxovanadium(IV), oxotitanium(IV) and dioxomolybdenum(VI) complexes with chiral imines of L-amino acids

Synthetic models for biological trinuclear copper clusters. Trinuclear and binuclear complexes derived from an octadentate tetraamine-tetrabenzimidazole ligand

The phenol ortho-oxygenation by mononuclear copper(I) complexes requires a dinuclear mu-eta2:eta2-peroxodicopper(II) complex rather than mononuclear CuO2 species

scientific article published on 01 March 2003

The protective and toxic role of neuromelanins in brain aging and Parkinson’s disease

artículo científico publicado en 2015

Trapping tyrosinase key active intermediate under turnover

artículo científico publicado en 2009

Tyrosinase Models. Synthesis, Structure, Catechol Oxidase Activity, and Phenol Monooxygenase Activity of a Dinuclear Copper Complex Derived from a Triamino Pentabenzimidazole Ligand ⬇️

artículo científico publicado el 9 de febrero de 1998

Tyrosinase catalyzes asymmetric sulfoxidation

artículo científico publicado en 2008

Tyrosinase-catalyzed oxidation of fluorophenols

artículo científico publicado en 2002

Tyrosinase-generated quinones induce covalent modification, unfolding, and aggregation of human holo-myoglobin

artículo científico publicado en 2007

Water‐Soluble Melanin–Protein–Fe/Cu Conjugates Derived from Norepinephrine as Reliable Models for Neuromelanin of Human Brain Locus Coeruleus

pH-dependent redox and CO binding properties of chelated protoheme-L-histidine and protoheme-glycyl-L-histidine complexes

artículo científico publicado en 2005

Lista de obras de

A Mn(II)-Mn(II) center in human prolidase.

A double arene hydroxylation mediated by dicopper(II)-hydroperoxide species

A new CuZ active form in the catalytic reduction of N(2)O by nitrous oxide reductase from Pseudomonas nautica.

A new dinuclear heme-copper complex derived from functionalized protoporphyrin IX.

Asymmetric oxidation of sulphides to sulphoxides catalysed by titanium complexes of N-salicylidene-L-amino acids

Axial Imidazole Distortion Effects on the Catalytic and Binding Properties of Chelated Deuterohemin Complexes

Biomimetic Modelling of Copper Enzymes: Synthesis, Characterization, EPR Analysis and Enantioselective Catalytic Oxidations by a New Chiral Trinuclear Copper(II) Complex

Catalytic activity, stability, unfolding, and degradation pathways of engineered and reconstituted myoglobins

Catalytic peroxidation of nitrogen monoxide and peroxynitrite by globins

Characterization and peroxidase activity of a myoglobin mutant containing a distal arginine

Coordination and redox properties of copper interaction with α-synuclein.

Copper(I) Forms a Redox-Stable 1:2 Complex with α-Synuclein N-Terminal Peptide in a Membrane-Like Environment.

Copper(I)-α-Synuclein Interaction: Structural Description of Two Independent and Competing Metal Binding Sites

Copper(I/II), α/β-Synuclein and Amyloid-β: Menage à Trois?

Copper-Aβ Peptides and Oxidation of Catecholic Substrates: Reactivity and Endogenous Peptide Damage.

Correction to Aminomethylene-Phosphonate Analogue as a Cu(II) Chelator: Characterization and Application as an Inhibitor of Oxidation Induced by Cu(II)-Prion Peptide Complex

Differences in the binding of copper(I) to α- and β-synuclein

Dopamin, oxidativer Stress und Protein‐Chinonmodifikationen bei Parkinson und anderen neurodegenerativen Erkrankungen

Easy oxidation and nitration of human myoglobin by nitrite and hydrogen peroxide

Effect of strain in the proximal ligand on the binding of nitric oxide and carbon monoxide to chelated protoheme complexes

Electron transfer complex between nitrous oxide reductase and cytochrome c552 from Pseudomonas nautica: kinetic, nuclear magnetic resonance, and docking studies

Endogenous arene hydroxylation promoted by copper(I) cluster helicates

Engineering peroxidase activity in myoglobin: the haem cavity structure and peroxide activation in the T67R/S92D mutant and its derivative reconstituted with protohaemin-l-histidine ⬇️

Formation of reactive nitrogen species at biologic heme centers: a potential mechanism of nitric oxide-dependent toxicity

Heme binding induces dimerization and nitration of truncated β-amyloid peptide Aβ16 under oxidative stress.

Hydroxylation of phenolic compounds by a peroxodicopper(II) complex: further insight into the mechanism of tyrosinase

Improved prolidase activity assay allowed enzyme kinetic characterization and faster prolidase deficiency diagnosis

Inhibitor binding studies on ascorbate oxidase ⬇️

Interaction between Hemin and Prion Peptides: Binding, Oxidative Reactivity and Aggregation

Interaction of Neuromelanin with Xenobiotics and Consequences for Neurodegeneration; Promising Experimental Models

Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease

Investigation of Streptomyces antibioticus tyrosinase reactivity toward chlorophenols

Investigation of azide binding to oxidized type 2 copper depleted ascorbate oxidase from Cucurbita pepo ⬇️

Kinetic and structural evidences on human prolidase pathological mutants suggest strategies for enzyme functional rescue

Kinetics and Thermodynamics of Halide and Nitrite Oxidation by Mammalian Heme Peroxidases

Ligand Binding, Conformational and Spectroscopic Properties, and Biomimetic Monooxygenase Activity by the Trinuclear Copper–PHI Complex Derived fromL-Histidine

Mechanistic insight into the activity of tyrosinase from variable-temperature studies in an aqueous/organic solvent

Mechanistic insight into the catechol oxidase activity by a biomimetic dinuclear copper complex

Mechanistic insight into the peroxidase catalyzed nitration of tyrosine derivatives by nitrite and hydrogen peroxide

Metmyoglobin-catalyzed exogenous and endogenous tyrosine nitration by nitrite and hydrogen peroxide

Modified microperoxidases exhibit different reactivity towards phenolic substrates

Modular syntheses of multidentate ligands with variable N-donors: applications to tri- and tetracopper(I) complexes

Myoglobin modification by enzyme-generated dopamine reactive species

Neuroglobin modification by reactive quinone species

Neuromelanin can protect against iron-mediated oxidative damage in system modeling iron overload of brain aging and Parkinson's disease

Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson's disease

Neuromelanin of the human substantia nigra: an update

Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson's disease.

Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role

New aspects of the reactivity of tyrosinase

Nickel binding to histone H4.

Nitric oxide releasing metal-diazeniumdiolate complexes strongly induce vasorelaxation and endothelial cell proliferation

Oxidase Reactivity of CuII Bound to N-Truncated Aβ Peptides Promoted by Dopamine ⬇️

Peroxidase catalyzed nitration of tryptophan derivatives. Mechanism, products and comparison with chemical nitrating agents

Probing the location of the substrate binding site of ascorbate oxidase near type 1 copper: an investigation through spectroscopic, inhibition and docking studies

Protein self-modification by heme-generated reactive species

Reactivity and endogenous modification by nitrite and hydrogen peroxide: does human neuroglobin act only as a scavenger?

Reactivity of copper-α-synuclein peptide complexes relevant to Parkinson's disease.

Reactivity study on microperoxidase-8 ⬇️

Redox reactivity of the heme Fe3+/Fe 2+ couple in native myoglobins and mutants with peroxidase-like activity

Remote His50 Acts as a Coordination Switch in the High-Affinity N-Terminal Centered Copper(II) Site of α-Synuclein.

Ruthenium anticancer drugs and proteins: a study of the interactions of the ruthenium(III) complex imidazolium trans-[tetrachloro(dimethyl sulfoxide)(imidazole)ruthenate(III)] with hen egg white lysozyme and horse heart cytochrome c

Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE.

Synthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis ⬇️

Synthesis, Structure, and Reactivity of Model Complexes of Copper Nitrite Reductase ⬇️

Synthesis, characterization and catalytic oxidations of oxovanadium(IV), oxotitanium(IV) and dioxomolybdenum(VI) complexes with chiral imines of L-amino acids

Synthetic models for biological trinuclear copper clusters. Trinuclear and binuclear complexes derived from an octadentate tetraamine-tetrabenzimidazole ligand

The phenol ortho-oxygenation by mononuclear copper(I) complexes requires a dinuclear mu-eta2:eta2-peroxodicopper(II) complex rather than mononuclear CuO2 species

The protective and toxic role of neuromelanins in brain aging and Parkinson’s disease

Trapping tyrosinase key active intermediate under turnover

Tyrosinase Models. Synthesis, Structure, Catechol Oxidase Activity, and Phenol Monooxygenase Activity of a Dinuclear Copper Complex Derived from a Triamino Pentabenzimidazole Ligand ⬇️

Tyrosinase catalyzes asymmetric sulfoxidation

Tyrosinase-catalyzed oxidation of fluorophenols

Tyrosinase-generated quinones induce covalent modification, unfolding, and aggregation of human holo-myoglobin

Water‐Soluble Melanin–Protein–Fe/Cu Conjugates Derived from Norepinephrine as Reliable Models for Neuromelanin of Human Brain Locus Coeruleus

Water‐Soluble Melanin–Protein–Fe/Cu Conjugates Derived from Norepinephrine as Reliable Models for Neuromelanin of Human Brain Locus Coeruleus

pH-dependent redox and CO binding properties of chelated protoheme-L-histidine and protoheme-glycyl-L-histidine complexes