Lista de obras -

A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.

artículo científico publicado en 2013

A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys

artículo científico publicado en 2015

ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2.

artículo científico publicado en 2016

Activated STAT3 is a mediator and biomarker of VEGF endothelial activation

artículo científico publicado en 2008

Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer.

artículo científico publicado en 2016

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.

artículo científico publicado en 2015

Alteration of developmental and pathological retinal angiogenesis in angptl4-deficient mice.

artículo científico publicado en 2011

Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor.

artículo científico publicado en 2011

Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis.

artículo científico publicado en 2009

Angiopoietin-1/Tie-2 activation contributes to vascular survival and tumor growth during VEGF blockade

artículo científico publicado en 2009

Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells

artículo científico publicado en 2006

Angiopoietin-2-driven vascular remodeling in airway inflammation

artículo científico publicado en 2010

Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation

artículo científico publicado en 2010

Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs

artículo científico publicado en 2017

C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice.

artículo científico publicado en 2016

CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors

artículo científico publicado en 2008

Complementary actions of VEGF and angiopoietin-1 on blood vessel growth and leakage

artículo científico publicado en 2002

Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system

artículo científico publicado en 2009

Dll4 blockade potentiates the anti-tumor effects of VEGF inhibition in renal cell carcinoma patient-derived xenografts

artículo científico publicado en 2014

Dll4-Notch signaling as a therapeutic target in tumor angiogenesis

artículo científico publicado en 2011

Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice

artículo científico publicado en 2012

Effect of VEGF and VEGF Trap on vascular endothelial cell signaling in tumors ⬇️

artículo científico publicado el 15 de diciembre de 2010

Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis

artículo científico publicado en 2009

Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer

artículo científico publicado en 2010

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

artículo científico publicado en 2004

In-silico discovery of cancer-specific peptide-HLA complexes for targeted therapy

artículo científico publicado en 2016

Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts

artículo científico publicado en 2004

Inhibitors of growth factor receptors, signaling pathways and angiogenesis as therapeutic molecular agents

artículo científico publicado en 2006

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis

artículo científico publicado en 2009

Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation

artículo científico publicado en 2016

Resistance to Anti-VEGF Therapy Mediated by Autocrine IL6/STAT3 Signaling and Overcome by IL6 Blockade

artículo científico publicado en 2016

Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis

artículo científico publicado en 2003

The Complex Role of Angiopoietin-2 in the Angiopoietin-Tie Signaling Pathway ⬇️

artículo científico publicado el 1 de septiembre de 2012

The anti-inflammatory actions of angiopoietin-1.

artículo científico publicado en 2005

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

artículo científico publicado en 2013

VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade

artículo científico publicado en 2007

VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis

artículo científico publicado en 2008

VEGF-mediated cross-talk within the neonatal murine thymus

artículo científico publicado en 2008

Vascular endothelial growth factor and other signaling pathways in developmental and pathologic angiogenesis

artículo científico publicado en 2004

Vascular endothelial growth factor blockade reduces plasma cytokines in a murine model of polymicrobial sepsis

artículo científico publicado en 2004

Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization

scientific journal article

Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis

scientific journal article

Lista de obras de

A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.

A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys

ANGPTL4-αvβ3 interaction counteracts hypoxia-induced vascular permeability by modulating Src signalling downstream of vascular endothelial growth factor receptor 2.

Activated STAT3 is a mediator and biomarker of VEGF endothelial activation

Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer.

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.

Alteration of developmental and pathological retinal angiogenesis in angptl4-deficient mice.

Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor.

Angiomodulin is a specific marker of vasculature and regulates vascular endothelial growth factor-A-dependent neoangiogenesis.

Angiopoietin-1/Tie-2 activation contributes to vascular survival and tumor growth during VEGF blockade

Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells

Angiopoietin-2-driven vascular remodeling in airway inflammation

Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation

Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs

C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice.

CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors

Complementary actions of VEGF and angiopoietin-1 on blood vessel growth and leakage

Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system

Dll4 blockade potentiates the anti-tumor effects of VEGF inhibition in renal cell carcinoma patient-derived xenografts

Dll4-Notch signaling as a therapeutic target in tumor angiogenesis

Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice

Effect of VEGF and VEGF Trap on vascular endothelial cell signaling in tumors ⬇️

Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis

Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

In-silico discovery of cancer-specific peptide-HLA complexes for targeted therapy

Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts

Inhibitors of growth factor receptors, signaling pathways and angiogenesis as therapeutic molecular agents

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis

Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation

Resistance to Anti-VEGF Therapy Mediated by Autocrine IL6/STAT3 Signaling and Overcome by IL6 Blockade

Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis

The Complex Role of Angiopoietin-2 in the Angiopoietin-Tie Signaling Pathway ⬇️

The anti-inflammatory actions of angiopoietin-1.

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade

VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis

VEGF-mediated cross-talk within the neonatal murine thymus

Vascular endothelial growth factor and other signaling pathways in developmental and pathologic angiogenesis

Vascular endothelial growth factor blockade reduces plasma cytokines in a murine model of polymicrobial sepsis

Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization

Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis