Lista de obras -

Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin

artículo científico publicado en 2018

Annotating the Plasmodium genome and the enigma of the shikimate pathway

artículo científico publicado en 2004

Artemisinin-(Iso)quinoline Hybrids by C-H Activation and Click Chemistry: Combating Multidrug-Resistant Malaria

artículo científico publicado en 2019

Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

artículo científico publicado en 2019

Assembly of the eukaryotic PLP-synthase complex from Plasmodium and activation of the Pdx1 enzyme

artículo científico publicado en 2012

Back Cover: Deeper Insight into the Six‐Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products (ChemistryOpen 3/2017).

artículo científico publicado en 2017

Deeper Insight into the Six-Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products.

artículo científico publicado en 2017

Defining the structural requirements for ribose 5-phosphate-binding and intersubunit cross-talk of the malarial pyridoxal 5-phosphate synthase

artículo científico publicado en 2010

Efficacy of Lefamulin Against Staphylococcus aureus-Induced Bacteremia in a Neutropenic and Immunocompetent Murine Model.

artículo científico publicado en 2017

Export of Plasmodium falciparum calcium-dependent protein kinase 1 to the parasitophorous vacuole is dependent on three N-terminal membrane anchor motifs

artículo científico publicado en 2004

Expression, purification and biochemical characterization of recombinant Ca-dependent protein kinase 2 of the malaria parasite Plasmodium falciparum

artículo científico publicado en 2013

Flavogenomics--a genomic and structural view of flavin-dependent proteins

artículo científico publicado en 2011

From compound to target: chemical proteomics and in silico screening identify Hsp90 and CDPK2 as putative targets in Plasmodium falciparum.

artículo científico publicado en 2012

Hexacyclinol, a new antiproliferative metabolite of Panus rudis HKI 0254.

artículo científico publicado en 2002

Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities

artículo científico publicado en 2015

Hybrid integration of scalable mechanical and magnetophoretic focusing for magnetic flow cytometry.

artículo científico publicado en 2018

Identification and characterization of novel small molecules as potent inhibitors of the plasmodial calcium-dependent protein kinase 1.

artículo científico publicado en 2009

Innenrücktitelbild: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. 37/2019)

artículo científico publicado en 2019

Inside Back Cover: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. Int. Ed. 37/2019)

artículo científico publicado en 2019

Label-free, high-throughput detection of P. falciparum infection in sphered erythrocytes with digital holographic microscopy

artículo científico publicado en 2018

Magnetic fingerprints of rolling cells for quantitative flow cytometry in whole blood

artículo científico publicado en 2016

Microtubule inhibitors as a potential treatment for malaria

artículo científico publicado en 2007

Minimally permutated peptide analogs as internal standards for relative and absolute quantification of peptides and proteins

artículo científico publicado en 2010

New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane-ferrocene hybrids

artículo científico publicado en 2015

PLP-dependent enzymes as potential drug targets for protozoan diseases

artículo científico publicado en 2011

Quantification of human complement factor H binding to asexual malaria blood stages by an enzyme-linked immunosorbent assay.

artículo científico publicado en 2018

Raf kinase inhibitor protein affects activity of Plasmodium falciparum calcium-dependent protein kinase 1

artículo científico publicado en 2007

SYBR® Green I-Based Fluorescence Assay to Assess Cell Viability of Malaria Parasites for Routine Use in Compound Screening

artículo científico publicado en 2017

Structural and thermodynamic insights into the assembly of the heteromeric pyridoxal phosphate synthase from Plasmodium falciparum

artículo científico publicado en 2007

Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer

scientific article published on 19 October 2018

Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells.

artículo científico publicado en 2017

Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents

artículo científico publicado en 2017

Synthesis of artemisinin-derived di/tri-mers and dendrimers, investigation of their activity against P. falciparum and cytomegalovirus, and insights into their mechanisms of action.

artículo científico publicado en 2018

Synthesis of new betulinic acid/betulin-derived dimers and hybrids with potent antimalarial and antiviral activities

scientific article published on 14 November 2018

The shikimate pathway in apicomplexan parasites: implications for drug development

artículo científico publicado en 2013

Two independent routes of de novo vitamin B6 biosynthesis: not that different after all.

artículo científico publicado en 2007

Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission

artículo científico publicado en 2015

Vitamin B6 biosynthesis by the malaria parasite Plasmodium falciparum: biochemical and structural insights

artículo científico publicado en 2005

Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis

scientific journal article

Vitamin and cofactor biosynthesis pathways in Plasmodium and other apicomplexan parasites

artículo científico publicado en 2007

Lista de obras de

Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin

Annotating the Plasmodium genome and the enigma of the shikimate pathway

Artemisinin-(Iso)quinoline Hybrids by C-H Activation and Click Chemistry: Combating Multidrug-Resistant Malaria

Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

Assembly of the eukaryotic PLP-synthase complex from Plasmodium and activation of the Pdx1 enzyme

Back Cover: Deeper Insight into the Six‐Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products (ChemistryOpen 3/2017).

Deeper Insight into the Six-Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products.

Defining the structural requirements for ribose 5-phosphate-binding and intersubunit cross-talk of the malarial pyridoxal 5-phosphate synthase

Efficacy of Lefamulin Against Staphylococcus aureus-Induced Bacteremia in a Neutropenic and Immunocompetent Murine Model.

Export of Plasmodium falciparum calcium-dependent protein kinase 1 to the parasitophorous vacuole is dependent on three N-terminal membrane anchor motifs

Expression, purification and biochemical characterization of recombinant Ca-dependent protein kinase 2 of the malaria parasite Plasmodium falciparum

Flavogenomics--a genomic and structural view of flavin-dependent proteins

From compound to target: chemical proteomics and in silico screening identify Hsp90 and CDPK2 as putative targets in Plasmodium falciparum.

Hexacyclinol, a new antiproliferative metabolite of Panus rudis HKI 0254.

Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities

Hybrid integration of scalable mechanical and magnetophoretic focusing for magnetic flow cytometry.

Identification and characterization of novel small molecules as potent inhibitors of the plasmodial calcium-dependent protein kinase 1.

Innenrücktitelbild: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. 37/2019)

Inside Back Cover: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. Int. Ed. 37/2019)

Label-free, high-throughput detection of P. falciparum infection in sphered erythrocytes with digital holographic microscopy

Magnetic fingerprints of rolling cells for quantitative flow cytometry in whole blood

Microtubule inhibitors as a potential treatment for malaria

Minimally permutated peptide analogs as internal standards for relative and absolute quantification of peptides and proteins

New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane-ferrocene hybrids

PLP-dependent enzymes as potential drug targets for protozoan diseases

Quantification of human complement factor H binding to asexual malaria blood stages by an enzyme-linked immunosorbent assay.

Raf kinase inhibitor protein affects activity of Plasmodium falciparum calcium-dependent protein kinase 1

SYBR® Green I-Based Fluorescence Assay to Assess Cell Viability of Malaria Parasites for Routine Use in Compound Screening

Structural and thermodynamic insights into the assembly of the heteromeric pyridoxal phosphate synthase from Plasmodium falciparum

Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer

Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells.

Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents

Synthesis of artemisinin-derived di/tri-mers and dendrimers, investigation of their activity against P. falciparum and cytomegalovirus, and insights into their mechanisms of action.

Synthesis of new betulinic acid/betulin-derived dimers and hybrids with potent antimalarial and antiviral activities

The shikimate pathway in apicomplexan parasites: implications for drug development

Two independent routes of de novo vitamin B6 biosynthesis: not that different after all.

Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission

Vitamin B6 biosynthesis by the malaria parasite Plasmodium falciparum: biochemical and structural insights

Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis

Vitamin and cofactor biosynthesis pathways in Plasmodium and other apicomplexan parasites