Lista de obras -

2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections ⬇️

artículo científico publicado el 18 de septiembre de 2010

A high yield optimized method for the production of acylated ACPs enabling the analysis of enzymes involved in P. falciparum fatty acid biosynthesis

artículo científico publicado en 2016

Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics

artículo científico publicado en 2009

Anthecularin: A Novel Sesquiterpene Lactone from Anthemis auriculata with Antiprotozoal Activity

artículo científico publicado en 2007

Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophularia lepidota roots

artículo científico publicado en 2005

Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica

artículo científico publicado en 2014

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis

artículo científico publicado en 2006

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

artículo científico publicado en 2008

ChemInform Abstract: Anthecularin (I): A Novel Sesquiterpene Lactone from Anthemis auriculata with Antiprotozoal Activity

artículo científico

Chemical constituents from Waltheria indica exert in vitro activity against Trypanosoma brucei and T. cruzi.

artículo científico publicado en 2015

Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation

artículo científico publicado en 2011

Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of Plasmodium falciparum enoyl-ACP-reductase (PfFabI)

artículo científico publicado en 2013

Expression, purification and biochemical characterization of recombinant Ca-dependent protein kinase 2 of the malaria parasite Plasmodium falciparum

artículo científico publicado en 2013

From compound to target: chemical proteomics and in silico screening identify Hsp90 and CDPK2 as putative targets in Plasmodium falciparum.

artículo científico publicado en 2012

Generation of Stilbene Antimicrobials against Multiresistant Strains of Staphylococcus aureus through Biotransformation by the Enzymatic Secretome of Botrytis cinerea

scientific article published on 24 July 2020

High-level expression and purification of human thymidine kinase 1: quaternary structure, stability, and kinetics

artículo científico publicado en 2006

In Silico Driven Design and Synthesis of Rhodanine Derivatives as Novel Antibacterials Targeting the Enoyl Reductase InhA.

artículo científico publicado en 2016

Inhibiting activities of the secondary metabolites of Phlomis brunneogaleata against parasitic protozoa and plasmodial enoyl-ACP Reductase, a crucial enzyme in fatty acid biosynthesis

artículo científico publicado en 2004

Inhibiting enoyl-ACP reductase (FabI) across pathogenic microorganisms by linear sesquiterpene lactones from Anthemis auriculata

artículo científico publicado en 2008

Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids

artículo científico publicado en 2006

Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli

artículo científico publicado en 2007

NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action

artículo científico publicado en 2011

Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism

artículo científico publicado en 2013

Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities

Non-covalent modification of granulocyte-colony stimulating factor (G-CSF) by coiled-coil technology

artículo científico publicado en 2016

Platelet Transforming Growth Factor-β1 Induces Liver Sinusoidal Endothelial Cells to Secrete Interleukin-6

artículo científico publicado en 2020

Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target

artículo científico publicado en 2013

Purine metabolite and energy charge analysis of Trypanosoma brucei cells in different growth phases using an optimized ion-pair RP-HPLC/UV for the quantification of adenine and guanine pools

artículo científico publicado en 2014

RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α

scientific article published on 12 August 2020

RNA pentaloop structures as effective targets of regulators belonging to the RsmA/CsrA protein family

artículo científico publicado en 2013

Recombinant expression and biochemical characterization of the unique elongating beta-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates.

artículo científico publicado en 2006

Single-molecule pulling simulations can discern active from inactive enzyme inhibitors

artículo científico publicado en 2010

Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase

artículo científico publicado en 2002

Structure-based drug design and in vitro testing reveal new inhibitors of enoyl-acyl carrier protein reductases

scientific article published on 02 June 2019

Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives

artículo científico publicado en 2007

Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities

artículo científico publicado en 2015

Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activity

artículo científico publicado en 2008

Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo

artículo científico publicado en 2011

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.

artículo científico publicado en 2018

Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data

artículo científico publicado en 2003

Temperature-Dependent NMR and CD Spectra ofβ-Peptides: On the Thermal Stability ofβ-Peptide Helices - Is the Folding Process ofβ-Peptides Non-cooperative?

The crystal structure of PfFabZ, the unique beta-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum.

artículo científico publicado en 2005

The pharmaceutical biochemistry group: where pharmaceutical chemistry meets biology and drug delivery.

artículo científico publicado en 2012

Thermodynamics of protein-ligand interactions: history, presence, and future aspects

artículo científico publicado en 2004

Lista de obras de

2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections ⬇️

A high yield optimized method for the production of acylated ACPs enabling the analysis of enzymes involved in P. falciparum fatty acid biosynthesis

Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics

Anthecularin: A Novel Sesquiterpene Lactone from Anthemis auriculata with Antiprotozoal Activity

Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophularia lepidota roots

Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

ChemInform Abstract: Anthecularin (I): A Novel Sesquiterpene Lactone from Anthemis auriculata with Antiprotozoal Activity

Chemical constituents from Waltheria indica exert in vitro activity against Trypanosoma brucei and T. cruzi.

Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation

Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of Plasmodium falciparum enoyl-ACP-reductase (PfFabI)

Expression, purification and biochemical characterization of recombinant Ca-dependent protein kinase 2 of the malaria parasite Plasmodium falciparum

From compound to target: chemical proteomics and in silico screening identify Hsp90 and CDPK2 as putative targets in Plasmodium falciparum.

Generation of Stilbene Antimicrobials against Multiresistant Strains of Staphylococcus aureus through Biotransformation by the Enzymatic Secretome of Botrytis cinerea

High-level expression and purification of human thymidine kinase 1: quaternary structure, stability, and kinetics

In Silico Driven Design and Synthesis of Rhodanine Derivatives as Novel Antibacterials Targeting the Enoyl Reductase InhA.

Inhibiting activities of the secondary metabolites of Phlomis brunneogaleata against parasitic protozoa and plasmodial enoyl-ACP Reductase, a crucial enzyme in fatty acid biosynthesis

Inhibiting enoyl-ACP reductase (FabI) across pathogenic microorganisms by linear sesquiterpene lactones from Anthemis auriculata

Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids

Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli

NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action

Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism

Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities

Non-covalent modification of granulocyte-colony stimulating factor (G-CSF) by coiled-coil technology

Platelet Transforming Growth Factor-β1 Induces Liver Sinusoidal Endothelial Cells to Secrete Interleukin-6

Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target

Purine metabolite and energy charge analysis of Trypanosoma brucei cells in different growth phases using an optimized ion-pair RP-HPLC/UV for the quantification of adenine and guanine pools

RIPK3-MLKL-Mediated Neutrophil Death Requires Concurrent Activation of Fibroblast Activation Protein-α

RNA pentaloop structures as effective targets of regulators belonging to the RsmA/CsrA protein family

Recombinant expression and biochemical characterization of the unique elongating beta-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates.

Single-molecule pulling simulations can discern active from inactive enzyme inhibitors

Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase

Structure-based drug design and in vitro testing reveal new inhibitors of enoyl-acyl carrier protein reductases

Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives

Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities

Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activity

Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo

Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.

Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data

Temperature-Dependent NMR and CD Spectra ofβ-Peptides: On the Thermal Stability ofβ-Peptide Helices - Is the Folding Process ofβ-Peptides Non-cooperative?

The crystal structure of PfFabZ, the unique beta-hydroxyacyl-ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum.

The pharmaceutical biochemistry group: where pharmaceutical chemistry meets biology and drug delivery.

Thermodynamics of protein-ligand interactions: history, presence, and future aspects