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A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma.

artículo científico publicado en 2007

A new mechanism of BRAF activation in human thyroid papillary carcinomas

artículo científico publicado en 2005

A truncated HMGA1 gene induces proliferation of the 3T3-L1 pre-adipocytic cells: a model of human lipomas

artículo científico publicado en 2003

Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells

artículo científico publicado en 2004

BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas

artículo científico publicado en 2003

Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels

artículo científico publicado en 2003

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

artículo científico publicado en 2002

Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors

artículo científico publicado en 2004

Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).

artículo científico publicado en 2003

Establishment of a non-tumorigenic papillary thyroid cell line (FB-2) carrying the RET/PTC1 rearrangement

artículo científico publicado en 2002

Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas

artículo científico publicado en 2004

HMGA2 mRNA expression correlates with the malignant phenotype in human thyroid neoplasias.

artículo científico publicado en 2008

Impairment of the p27kip1 function enhances thyroid carcinogenesis in TRK-T1 transgenic mice

artículo científico publicado en 2009

Inhibitory effects of peroxisome poliferator-activated receptor gamma on thyroid carcinoma cell growth

artículo científico publicado en 2002

Mitogenic effects of the up-regulation of minichromosome maintenance proteins in anaplastic thyroid carcinoma

artículo científico publicado en 2005

Molecular profile of hyalinizing trabecular tumours of the thyroid: high prevalence of RET/PTC rearrangements and absence of B-raf and N-ras point mutations.

artículo científico publicado en 2005

Mutation of the PIK3CA gene in anaplastic thyroid cancer.

artículo científico publicado en 2005

NCOA4 transcriptional coactivator inhibits activation of DNA replication origins

artículo científico publicado en 2014

RET activation and clinicopathologic features in poorly differentiated thyroid tumors

artículo científico publicado en 2002

RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture

artículo científico publicado en 2006

RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma.

artículo científico publicado en 2006

RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase.

artículo científico

Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes

artículo científico publicado en 2003

Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cells.

artículo científico publicado en 2004

TWIST1 plays a pleiotropic role in determining the anaplastic thyroid cancer phenotype

artículo científico publicado en 2011

The RET/PTC oncogene is frequently activated in oncocytic thyroid tumors (Hurthle cell adenomas and carcinomas), but not in oncocytic hyperplastic lesions

artículo científico publicado en 2002

The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

artículo científico publicado en 2005

The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation.

artículo científico publicado en 2009

The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues

artículo científico publicado en 2002

The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins

artículo científico publicado en 2006

Tumor suppressor role of the CL2/DRO1/CCDC80 gene in thyroid carcinogenesis

artículo científico publicado en 2013

siRNA nanoformulation against the ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma

artículo científico publicado en 2007