Lista de obras -

A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity.

artículo científico publicado en 2016

A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease.

artículo científico publicado en 2016

Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis

artículo científico publicado en 2013

Curdlan-mediated regulation of human phagocyte-specific chitotriosidase.

artículo científico publicado en 2010

Design and synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates

artículo científico publicado en 2014

Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake

artículo científico publicado en 2015

Differential use of E2 ubiquitin conjugating enzymes for regulated degradation of the rate-limiting enzymes HMGCR and SQLE in cholesterol biosynthesis

scientific article published on 23 December 2018

EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux.

artículo científico publicado en 2017

Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response

artículo científico publicado en 2011

Endo-β-Glucosidase Tag Allows Dual Detection of Fusion Proteins by Fluorescent Mechanism-Based Probes and Activity Measurement.

artículo científico publicado en 2016

Fasting reduces liver fibrosis in a mouse model for chronic cholangiopathies

artículo científico publicado en 2013

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases

artículo científico publicado en 2016

HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution.

artículo científico publicado en 2018

Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis

artículo científico publicado en 2017

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism

scientific article published on 28 February 2020

Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors

artículo científico publicado en 2014

Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism

artículo científico publicado en 2015

Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene

artículo científico publicado en 2017

In vitro and in vivo comparative and competitive activity-based protein profiling of GH29 α-l-fucosidases.

artículo científico publicado en 2015

Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice

artículo científico publicado en 2018

Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes

artículo científico publicado en 2017

LIM-only protein FHL2 is a positive regulator of liver X receptors in smooth muscle cells involved in lipid homeostasis

artículo científico publicado en 2014

Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidases

artículo científico publicado en 2016

N-azidoacetylmannosamine-mediated chemical tagging of gangliosides

artículo científico publicado en 2007

Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.

artículo científico publicado en 2012

Potent and Selective Activity-Based Probes for GH27 Human Retaining α-Galactosidases

artículo científico publicado en 2014

Reduction of glycosphingolipid biosynthesis stimulates biliary lipid secretion in mice

artículo científico publicado en 2009

Regulation of intestinal LDLR by the LXR-IDOL axis

artículo científico publicado en 2020

Stabilization of Glucocerebrosidase by Active Site Occupancy.

artículo científico publicado en 2017

TLR- and NOD2-dependent regulation of human phagocyte-specific chitotriosidase

artículo científico publicado en 2007

The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1

artículo científico publicado en 2019

The glucosylceramide synthase inhibitor N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin induces sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in HepG2 cells.

artículo científico publicado en 2008

Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma

artículo científico publicado en 2022

Unexpected effects of fasting on murine lipid homeostasis--transcriptomic and lipid profiling

artículo científico publicado en 2010

Very low serum adiponectin levels in patients with type 1 Gaucher disease without overt hyperglycemia

scientific article published on 01 March 2007

Lista de obras de

A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity.

A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease.

Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis

Curdlan-mediated regulation of human phagocyte-specific chitotriosidase.

Design and synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates

Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake

Differential use of E2 ubiquitin conjugating enzymes for regulated degradation of the rate-limiting enzymes HMGCR and SQLE in cholesterol biosynthesis

EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux.

Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response

Endo-β-Glucosidase Tag Allows Dual Detection of Fusion Proteins by Fluorescent Mechanism-Based Probes and Activity Measurement.

Fasting reduces liver fibrosis in a mouse model for chronic cholangiopathies

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases

HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution.

Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism

Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors

Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism

Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene

In vitro and in vivo comparative and competitive activity-based protein profiling of GH29 α-l-fucosidases.

Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice

Investigations on therapeutic glucocerebrosidases through paired detection with fluorescent activity-based probes

LIM-only protein FHL2 is a positive regulator of liver X receptors in smooth muscle cells involved in lipid homeostasis

Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidases

N-azidoacetylmannosamine-mediated chemical tagging of gangliosides

Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.

Potent and Selective Activity-Based Probes for GH27 Human Retaining α-Galactosidases

Reduction of glycosphingolipid biosynthesis stimulates biliary lipid secretion in mice

Regulation of intestinal LDLR by the LXR-IDOL axis

Stabilization of Glucocerebrosidase by Active Site Occupancy.

TLR- and NOD2-dependent regulation of human phagocyte-specific chitotriosidase

The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1

The glucosylceramide synthase inhibitor N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin induces sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in HepG2 cells.

Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma

Unexpected effects of fasting on murine lipid homeostasis--transcriptomic and lipid profiling

Very low serum adiponectin levels in patients with type 1 Gaucher disease without overt hyperglycemia