Lista de obras -

A Hot-Segment-Based Approach for the Design of Cross-Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self-Assembly

artículo científico publicado en 2015

Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdala

artículo científico publicado en 2008

Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels.

artículo científico publicado en 2013

Activation of kappa opioid receptors decreases synaptic transmission and inhibits long-term potentiation in the basolateral amygdala of the mouse

artículo científico publicado en 2008

Activation of mGlu receptors induces LTD without affecting postsynaptic sensitivity of CA1 neurons in rat hippocampal slices.

artículo científico publicado en 2003

Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouse

artículo científico publicado en 2003

Anesthesia and postoperative cognitive dysfunction (POCD).

artículo científico publicado en 2009

Anesthetics Promoting in vitro AβPP Metabolism and Amyloid-β Toxicity ⬇️

artículo científico publicado el 1 de enero de 2010

Antidepressants and antipsychotic drugs colocalize with 5-HT3 receptors in raft-like domains.

artículo científico publicado en 2005

Cannabinoid receptor type 1 located on presynaptic terminals of principal neurons in the forebrain controls glutamatergic synaptic transmission.

artículo científico publicado en 2006

Cannabinoids in anaesthesia and pain therapy

artículo científico publicado en 2005

Chronic social stress during adolescence induces cognitive impairment in aged mice.

artículo científico publicado en 2010

Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling.

artículo científico publicado en 2004

Cloned human and murine serotonin(3A) receptors expressed in human embryonic kidney 293 cells display different single-channel kinetics

artículo científico publicado en 2002

Corticotropin-releasing factor (CRF) receptor type 1-dependent modulation of synaptic plasticity

artículo científico publicado en 2007

DNA Damage, Neurodegeneration, and Synaptic Plasticity

artículo científico publicado en 2016

Designed Macrocyclic Peptides as Nanomolar Amyloid Inhibitors Based on Minimal Recognition Elements

artículo científico publicado en 2018

Distribution and properties of functional postsynaptic kainate receptors on neocortical layer V pyramidal neurons.

artículo científico publicado en 2003

Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors

scientific journal article

Forebrain CRF₁ modulates early-life stress-programmed cognitive deficits

artículo científico publicado en 2011

GABA(A) receptor activation and open-channel block by volatile anaesthetics: a new principle of receptor modulation?

artículo científico publicado en 2002

Identification of a domain which affects kinetics and antagonistic potency of clozapine at 5-HT3 receptors

artículo científico publicado en 2009

Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments

artículo científico publicado en 2015

Impact of lipid raft integrity on 5-HT3 receptor function and its modulation by antidepressants.

artículo científico publicado en 2010

Infrared-guided laser stimulation as a tool for elucidating the synaptic site of expression of long-term synaptic plasticity

artículo científico publicado en 2007

Intracerebroventricular injection of beta-amyloid in mice is associated with long-term cognitive impairment in the modified hole-board test.

artículo científico publicado en 2017

Isoflurane anaesthesia reversibly improves cognitive function and long-term potentiation (LTP) via an up-regulation in NMDA receptor 2B subunit expression.

artículo científico publicado en 2008

Isoflurane and sevoflurane dose-dependently impair hippocampal long-term potentiation

artículo científico publicado en 2009

Isoflurane reduces glutamatergic transmission in neurons in the spinal cord superficial dorsal horn: evidence for a presynaptic site of an analgesic action

artículo científico publicado en 2004

Lack of association of the 5‐HT3A receptor with schizophrenia ⬇️

artículo científico publicado el 10 de febrero de 2012

Lipid raft integrity affects GABAA receptor, but not NMDA receptor modulation by psychopharmacological compounds

artículo científico publicado en 2012

MRZ-99030 - A novel modulator of Aβ aggregation: I - Mechanism of action (MoA) underlying the potential neuroprotective treatment of Alzheimer's disease, glaucoma and age-related macular degeneration (AMD).

artículo científico publicado en 2015

MRZ-99030 - A novel modulator of Aβ aggregation: II - Reversal of Aβ oligomer-induced deficits in long-term potentiation (LTP) and cognitive performance in rats and mice

artículo científico publicado en 2015

Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice

artículo científico publicado en 2009

Modulation of ligand-gated ion channels by antidepressants and antipsychotics

artículo científico publicado en 2007

Neramexane (merz pharmaceuticals/forest laboratories).

artículo científico publicado en 2006

Neramexane: a moderate-affinity NMDA receptor channel blocker: new prospects and indications

artículo científico publicado en 2009

Nitrous oxide (N2O) pre- and postsynaptically attenuates NMDA receptor-mediated neurotransmission in the amygdala

artículo científico publicado en 2006

Preclinical to phase II amyloid beta (Aβ) peptide modulators under investigation for Alzheimer's disease

artículo científico publicado en 2017

Recent Developments in Potential Anxiolytic Agents Targeting GABAA/BzR Complex or the Translocator Protein (18kDa) (TSPO) ⬇️

artículo científico publicado el 1 de enero de 2012

Reduced anxiety, conditioned fear, and hippocampal long-term potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice

artículo científico publicado en 2007

Remote and reversible inhibition of neurons and circuits by small molecule induced potassium channel stabilization

artículo científico publicado en 2016

Selectively N‐Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self‐Assembly of Both IAPP and Aβ40 ⬇️

artículo científico publicado el 19 de agosto de 2013

Sevoflurane Anesthesia Improves Cognitive Performance in Mice, but Does Not Influence In Vitro Long-Term Potentation in Hippocampus CA1 Stratum Radiatum ⬇️

artículo científico publicado el 28 de mayo de 2013

The endogenous cannabinoid system controls extinction of aversive memories

artículo científico publicado en 2002

The potassium channel modulator flupirtine shifts the frequency-response function of hippocampal synapses to favour LTD in mice

artículo científico publicado en 2004

The xenon-mediated antagonism against the NMDA receptor is non-selective for receptors containing either NR2A or NR2B subunits in the mouse amygdala.

artículo científico publicado en 2009

Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects

artículo científico publicado en 2009

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

artículo científico publicado en 2010

Xenon attenuates excitatory synaptic transmission in the rodent prefrontal cortex and spinal cord dorsal horn

artículo científico publicado en 2009

Xenon reduces N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated synaptic transmission in the amygdala

artículo científico publicado en 2008

Lista de obras de

A Hot-Segment-Based Approach for the Design of Cross-Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self-Assembly

Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdala

Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels.

Activation of kappa opioid receptors decreases synaptic transmission and inhibits long-term potentiation in the basolateral amygdala of the mouse

Activation of mGlu receptors induces LTD without affecting postsynaptic sensitivity of CA1 neurons in rat hippocampal slices.

Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouse

Anesthesia and postoperative cognitive dysfunction (POCD).

Anesthetics Promoting in vitro AβPP Metabolism and Amyloid-β Toxicity ⬇️

Antidepressants and antipsychotic drugs colocalize with 5-HT3 receptors in raft-like domains.

Cannabinoid receptor type 1 located on presynaptic terminals of principal neurons in the forebrain controls glutamatergic synaptic transmission.

Cannabinoids in anaesthesia and pain therapy

Chronic social stress during adolescence induces cognitive impairment in aged mice.

Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling.

Cloned human and murine serotonin(3A) receptors expressed in human embryonic kidney 293 cells display different single-channel kinetics

Corticotropin-releasing factor (CRF) receptor type 1-dependent modulation of synaptic plasticity

DNA Damage, Neurodegeneration, and Synaptic Plasticity

Designed Macrocyclic Peptides as Nanomolar Amyloid Inhibitors Based on Minimal Recognition Elements

Distribution and properties of functional postsynaptic kainate receptors on neocortical layer V pyramidal neurons.

Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors

Forebrain CRF₁ modulates early-life stress-programmed cognitive deficits

GABA(A) receptor activation and open-channel block by volatile anaesthetics: a new principle of receptor modulation?

Identification of a domain which affects kinetics and antagonistic potency of clozapine at 5-HT3 receptors

Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments

Impact of lipid raft integrity on 5-HT3 receptor function and its modulation by antidepressants.

Infrared-guided laser stimulation as a tool for elucidating the synaptic site of expression of long-term synaptic plasticity

Intracerebroventricular injection of beta-amyloid in mice is associated with long-term cognitive impairment in the modified hole-board test.

Isoflurane anaesthesia reversibly improves cognitive function and long-term potentiation (LTP) via an up-regulation in NMDA receptor 2B subunit expression.

Isoflurane and sevoflurane dose-dependently impair hippocampal long-term potentiation

Isoflurane reduces glutamatergic transmission in neurons in the spinal cord superficial dorsal horn: evidence for a presynaptic site of an analgesic action

Lack of association of the 5‐HT3A receptor with schizophrenia ⬇️

Lipid raft integrity affects GABAA receptor, but not NMDA receptor modulation by psychopharmacological compounds

MRZ-99030 - A novel modulator of Aβ aggregation: I - Mechanism of action (MoA) underlying the potential neuroprotective treatment of Alzheimer's disease, glaucoma and age-related macular degeneration (AMD).

MRZ-99030 - A novel modulator of Aβ aggregation: II - Reversal of Aβ oligomer-induced deficits in long-term potentiation (LTP) and cognitive performance in rats and mice

Memantine improves cognition and reduces Alzheimer's-like neuropathology in transgenic mice

Modulation of ligand-gated ion channels by antidepressants and antipsychotics

Neramexane (merz pharmaceuticals/forest laboratories).

Neramexane: a moderate-affinity NMDA receptor channel blocker: new prospects and indications

Nitrous oxide (N2O) pre- and postsynaptically attenuates NMDA receptor-mediated neurotransmission in the amygdala

Preclinical to phase II amyloid beta (Aβ) peptide modulators under investigation for Alzheimer's disease

Recent Developments in Potential Anxiolytic Agents Targeting GABAA/BzR Complex or the Translocator Protein (18kDa) (TSPO) ⬇️

Reduced anxiety, conditioned fear, and hippocampal long-term potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice

Remote and reversible inhibition of neurons and circuits by small molecule induced potassium channel stabilization

Selectively N‐Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self‐Assembly of Both IAPP and Aβ40 ⬇️

Sevoflurane Anesthesia Improves Cognitive Performance in Mice, but Does Not Influence In Vitro Long-Term Potentation in Hippocampus CA1 Stratum Radiatum ⬇️

The endogenous cannabinoid system controls extinction of aversive memories

The potassium channel modulator flupirtine shifts the frequency-response function of hippocampal synapses to favour LTD in mice

The xenon-mediated antagonism against the NMDA receptor is non-selective for receptors containing either NR2A or NR2B subunits in the mouse amygdala.

Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

Xenon attenuates excitatory synaptic transmission in the rodent prefrontal cortex and spinal cord dorsal horn

Xenon reduces N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated synaptic transmission in the amygdala