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A Hot-Segment-Based Approach for the Design of Cross-Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self-Assembly.

artículo científico publicado en 2015

Blocking Inflammasome Activation Caused by β-Amyloid Peptide (Aβ) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic

scientific article published on 25 July 2019

Cross-amyloid interaction of Aβ and IAPP at lipid membranes

artículo científico publicado en 2011

Crystal-state 3D-structural characterization of novel, Aib-based, turn and helical peptides

artículo científico publicado en 2007

Dissecting the role of single regions of an IAPP mimic and IAPP in inhibition of Aβ40 amyloid formation and cytotoxicity.

artículo científico publicado en 2011

Exploiting cross-amyloid interactions to inhibit protein aggregation but not function: nanomolar affinity inhibition of insulin aggregation by an IAPP mimic

artículo científico publicado en 2008

Handedness control of peptide helices by amino acid side-chain chirality: Ile/aIle peptides

article

IAPP mimic blocks Abeta cytotoxic self-assembly: cross-suppression of amyloid toxicity of Abeta and IAPP suggests a molecular link between Alzheimer's disease and type II diabetes

scientific article published on 01 January 2007

Identification of hot regions of the Abeta-IAPP interaction interface as high-affinity binding sites in both cross- and self-association

artículo científico publicado en 2010

Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide

artículo científico publicado en 2011

MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism

artículo científico publicado en 2010

Screening of the binding properties of molecularly imprinted nanoparticles via capillary electrophoresis.

artículo científico publicado en 2016

Selectively N-methylated soluble IAPP mimics as potent IAPP receptor agonists and nanomolar inhibitors of cytotoxic self-assembly of both IAPP and Aβ40.

artículo científico publicado en 2013

Surface plasmon resonance based on molecularly imprinted nanoparticles for the picomolar detection of the iron regulating hormone Hepcidin-25. ⬇️

artículo científico publicado en 2015

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