Lista de obras -

'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans

artículo científico publicado en 2012

A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo.

artículo científico publicado en 2009

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

artículo científico publicado en 2011

An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

artículo científico publicado en 2011

Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes

artículo científico publicado en 2009

Bayesian Network Inference Enables Unbiased Phenotypic Anchoring of Transcriptomic Responses to Cigarette Smoke in Humans

artículo científico publicado en 2015

Benzo[a]pyrene-Induced Changes in MicroRNA–mRNA Networks ⬇️

artículo científico publicado el 22 de febrero de 2012

Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks

artículo científico publicado en 2013

Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs

artículo científico publicado en 2006

Classification of Hepatotoxicants Using HepG2 Cells: A Proof of Principle Study

artículo científico publicado en 2014

Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution

artículo científico publicado en 2008

Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification

artículo científico publicado en 2010

Comparison of coumarin-induced toxicity between sandwich-cultured primary rat hepatocytes and rats in vivo: a toxicogenomics approach

scientific article published on 08 September 2006

Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data

artículo científico publicado en 2012

Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver

artículo científico publicado en 2012

Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time

artículo científico publicado en 2009

Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes

artículo científico publicado en 2011

Free radical scavenging and formation by multi-walled carbon nanotubes in cell free conditions and in human bronchial epithelial cells

artículo científico publicado en 2014

Gender-specific transcriptomic response to environmental exposure in Flemish adults

artículo científico publicado en 2013

Genomic analysis suggests higher susceptibility of children to air pollution

artículo científico publicado en 2008

Global gene expression analysis in cord blood reveals gender-specific differences in response to carcinogenic exposure in utero

artículo científico publicado en 2012

Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity

artículo científico publicado en 2011

Integrating multiple omics to unravel mechanisms of Cyclosporin A induced hepatotoxicity in vitro

artículo científico publicado en 2015

Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells

artículo científico publicado en 2011

Interactions between polycyclic aromatic hydrocarbons in binary mixtures: effects on gene expression and DNA adduct formation in precision-cut rat liver slices

artículo científico publicado en 2008

Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes

artículo científico publicado en 2015

Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices

artículo científico publicado en 2014

Mechanisms of colorectal and lung cancer prevention by vegetables: a genomic approach

artículo científico publicado en 2007

Methylation status of CpG islands in the promoter region of genes differentially expressed in colonic mucosa from adenoma patients and controls in response to altered vegetable intake.

artículo científico publicado en 2009

Micronuclei in cord blood lymphocytes and associations with biomarkers of exposure to carcinogens and hormonally active factors, gene polymorphisms, and gene expression: the NewGeneris cohort ⬇️

artículo científico publicado en 2013

Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency

artículo científico

Multiplex genotyping as a biomarker for susceptibility to carcinogenic exposure in the FLEHS biomonitoring study

artículo científico publicado en 2008

New insights into BaP-induced toxicity: role of major metabolites in transcriptomics and contribution to hepatocarcinogenesis

artículo científico publicado en 2016

Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.

artículo científico publicado en 2008

Performance of in vitro γH2AX assay in HepG2 cells to predict in vivo genotoxicity

artículo científico publicado en 2012

Potential role of cytochrome P450-1B1 in the metabolic activation of 4-aminobiphenyl in humans

artículo científico publicado en 2009

Prenatal exposure to polychlorinated biphenyls and dioxins is associated with increased risk of wheeze and infections in infants

artículo científico publicado en 2011

Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study

artículo científico publicado en 2011

Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells ⬇️

artículo científico publicado el 16 de diciembre de 2010

Proteomics in the search for mechanisms and biomarkers of drug-induced hepatotoxicity ⬇️

artículo científico publicado el 17 de enero de 2012

RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene

artículo científico publicado en 2012

Screening for Drug-Induced Hepatotoxicity in Primary Mouse Hepatocytes Using Acetaminophen, Amiodarone, and Cyclosporin A as Model Compounds: An Omics-Guided Approach ⬇️

artículo científico publicado el 11 de enero de 2013

Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?

artículo científico publicado en 2014

The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays

artículo científico publicado en 2008

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

artículo científico publicado en 2014

Time series analysis of benzo[A]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets

artículo científico publicado en 2010

Transcriptome analysis in peripheral blood of humans exposed to environmental carcinogens: a promising new biomarker in environmental health studies.

artículo científico publicado en 2008

Transcriptomic profile indicative of immunotoxic exposure: in vitro studies in peripheral blood mononuclear cells

artículo científico publicado en 2010

Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

artículo científico publicado en 2013

Use of spermatozoal mRNA profiles to study gene-environment interactions in human germ cells

artículo científico publicado en 2009

Vegetables Affect the Expression of Genes Involved in Anticarcinogenic Processes in the Colonic Mucosa of C57Bl/6 Female Mice

article

Lista de obras de

'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans

A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo.

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes

Bayesian Network Inference Enables Unbiased Phenotypic Anchoring of Transcriptomic Responses to Cigarette Smoke in Humans

Benzo[a]pyrene-Induced Changes in MicroRNA–mRNA Networks ⬇️

Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks

Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs

Classification of Hepatotoxicants Using HepG2 Cells: A Proof of Principle Study

Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution

Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification

Comparison of coumarin-induced toxicity between sandwich-cultured primary rat hepatocytes and rats in vivo: a toxicogenomics approach

Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data

Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver

Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time

Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes

Free radical scavenging and formation by multi-walled carbon nanotubes in cell free conditions and in human bronchial epithelial cells

Gender-specific transcriptomic response to environmental exposure in Flemish adults

Genomic analysis suggests higher susceptibility of children to air pollution

Global gene expression analysis in cord blood reveals gender-specific differences in response to carcinogenic exposure in utero

Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity

Integrating multiple omics to unravel mechanisms of Cyclosporin A induced hepatotoxicity in vitro

Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells

Interactions between polycyclic aromatic hydrocarbons in binary mixtures: effects on gene expression and DNA adduct formation in precision-cut rat liver slices

Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes

Interindividual variation in response to xenobiotic exposure established in precision-cut human liver slices

Mechanisms of colorectal and lung cancer prevention by vegetables: a genomic approach

Methylation status of CpG islands in the promoter region of genes differentially expressed in colonic mucosa from adenoma patients and controls in response to altered vegetable intake.

Micronuclei in cord blood lymphocytes and associations with biomarkers of exposure to carcinogens and hormonally active factors, gene polymorphisms, and gene expression: the NewGeneris cohort ⬇️

Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency

Multiplex genotyping as a biomarker for susceptibility to carcinogenic exposure in the FLEHS biomonitoring study

New insights into BaP-induced toxicity: role of major metabolites in transcriptomics and contribution to hepatocarcinogenesis

Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.

Performance of in vitro γH2AX assay in HepG2 cells to predict in vivo genotoxicity

Potential role of cytochrome P450-1B1 in the metabolic activation of 4-aminobiphenyl in humans

Prenatal exposure to polychlorinated biphenyls and dioxins is associated with increased risk of wheeze and infections in infants

Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study

Proteomics Investigations of Drug-Induced Hepatotoxicity in HepG2 Cells ⬇️

Proteomics in the search for mechanisms and biomarkers of drug-induced hepatotoxicity ⬇️

RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene

Screening for Drug-Induced Hepatotoxicity in Primary Mouse Hepatocytes Using Acetaminophen, Amiodarone, and Cyclosporin A as Model Compounds: An Omics-Guided Approach ⬇️

Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?

The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

Time series analysis of benzo[A]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets

Transcriptome analysis in peripheral blood of humans exposed to environmental carcinogens: a promising new biomarker in environmental health studies.

Transcriptomic profile indicative of immunotoxic exposure: in vitro studies in peripheral blood mononuclear cells

Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

Use of spermatozoal mRNA profiles to study gene-environment interactions in human germ cells

Vegetables Affect the Expression of Genes Involved in Anticarcinogenic Processes in the Colonic Mucosa of C57Bl/6 Female Mice