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A new flavanone glycoside from the dried immature fruits of Poncirus trifoliata ⬇️

artículo científico publicado en 2007

A novel vesicular carrier, transethosome, for enhanced skin delivery of voriconazole: Characterization and in vitro/in vivo evaluation ⬇️

artículo científico publicado el 17 de diciembre de 2011

Addition of amino acid moieties to lapatinib increases the anti-cancer effect via amino acid transporters

artículo científico publicado en 2013

Advanced formulation and pharmacological activity of hydrogel of the titrated extract of C. asiatica

artículo científico publicado en 2005

Air-liquid interface (ALI) culture of human bronchial epithelial cell monolayers as an in vitro model for airway drug transport studies

artículo científico publicado en 2007

Altered metabolism of orally administered loxoprofen in human subjects after an oral administration of loxoprofen for three consecutive days followed by a seven-day washout

artículo científico publicado en 2002

Altered pharmacokinetics and hepatic uptake of TBuMA in ethynylestradiol-induced cholestasis

scientific article published on 01 April 2006

Altered pharmacokinetics of daunorubicin in rats with CCl4-induced hepatic injury

artículo científico publicado en 2007

An aqueous extract of Poncirus fructus activates the prokinetic activity of 5-HT receptor subtype 4 without hERG interaction.

artículo científico publicado en 2010

An improved prediction of the human in vivo intestinal permeability and BCS class of drugs using the in vitro permeability ratio obtained for rat intestine using an Ussing chamber system

artículo científico publicado en 2012

Anticancer efficacy of photodynamic therapy with hematoporphyrin-modified, doxorubicin-loaded nanoparticles in liver cancer

scientific article published on 24 July 2014

Antifibrotic effect of MMP13-encoding plasmid DNA delivered using polyethylenimine shielded with hyaluronic acid

artículo científico publicado en 2010

Antitumor effect of paclitaxel-loaded PEGylated immunoliposomes against human breast cancer cells

artículo científico publicado en 2007

Application of a sample pooling method for the accelerated assessment of the rate of uptake of drugs by the brain in rats

artículo científico publicado en 2006

Assessment of siRNA pharmacokinetics using ELISA-based quantification

artículo científico publicado en 2009

Biliary clearance of bromosulfophthalein in anesthetized and freely moving conscious rat.

artículo científico publicado en 2009

Characterization and in vitro evaluation of freeze-dried microparticles composed of granisetron-cyclodextrin complex and carboxymethylcellulose for intranasal delivery.

artículo científico publicado en 2010

Characterization of the transport of uracil across Caco-2 and LLC-PK1 cell monolayers

artículo científico publicado en 2002

Chitosan microspheres as an alveolar macrophage delivery system of ofloxacin via pulmonary inhalation

scientific article published on 08 November 2012

Chitosan oligosaccharide-arachidic acid-based nanoparticles for anti-cancer drug delivery

artículo científico publicado en 2012

Clinical pharmacokinetics of oxaliplatin and 5-fluorouracil administered in combination with leucovorin in Korean patients with advanced colorectal cancer.

artículo científico publicado en 2006

Comparative in vitro release and clinical pharmacokinetics of leuprolide from Luphere 3M Depot, a 3-month release formulation of leuprolide acetate

artículo científico publicado en 2016

Comparison of pharmacokinetics of loxoprofen and its active metabolites after an intravenous, intramuscular, and oral administration of loxoprofen in rats: evidence for extrahepatic metabolism.

artículo científico publicado en 2005

Contribution of a significant first-pass effect of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate in the liver to its poor bioavailability in rats

artículo científico publicado en 2009

Contribution of ion-pair complexation with bile salts to the transport of organic cations across LLC-PK1 cell monolayers

artículo científico publicado el 1 de abril de 2003

Decreased secretory transport of a quarternary ammonium, TBuMA, across LLC-PK1 cells by the anionic kidney extract

artículo científico publicado en 2008

Determination of Belotecan in the Plasma, Bile, and Urine of Rats by High-Performance Liquid Chromatography with Fluorescence Detection and Its Application to a Pharmacokinetic Study

Determination of zabofloxacin in rat plasma by liquid chromatography with mass spectrometry and its application to pharmacokinetic study ⬇️

artículo científico publicado el 9 de noviembre de 2010

Differential changes in functional activity of organic cation transporters in rats with uranyl nitrate-induced acute renal failure

artículo científico publicado en 2012

Docetaxel microemulsion for enhanced oral bioavailability: preparation and in vitro and in vivo evaluation

artículo científico publicado en 2009

Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium

artículo científico publicado en 2005

Effect of a new hepatoprotective agent, YH-439, on the hepatobiliary transport of organic cations (OCs): selective inhibition of sinusoidal OCs uptake without influencing glucose uptake and canalicular OCs excretion

artículo científico publicado en 2005

Effect of an aqueous extract of dried immature fruit of Poncirus trifoliata (L.) Raf. on intestinal transit in rodents with experimental gastrointestinal motility dysfunctions

artículo científico publicado en 2005

Effect of excipients on the stability and transport of recombinant human epidermal growth factor (rhEGF) across CACO-2 cell monolayers ⬇️

artículo científico publicado el 1 de abril de 2003

Effect of fatty acids on the transdermal delivery of donepezil: In vitro and in vivo evaluation ⬇️

artículo científico publicado el 20 de octubre de 2011

Effect of ion-pair formation with bile salts on the in vitro cellular transport of berberine

artículo científico publicado en 2008

Effect of nitric oxide on the sinusoidal uptake of organic cations and anions by isolated hepatocytes

artículo científico publicado en 2002

Effect of nonylphenol ethoxylates (NPEs) on barrier functions of epithelial cell membranes: opening of tight junctions and competitive inhibition of P-gp-mediated efflux

artículo científico publicado en 2005

Effect of permeation enhancers on transdermal delivery of fluoxetine: in vitro and in vivo evaluation

artículo científico publicado en 2013

Effect of probenecid on the biliary excretion of belotecan

artículo científico publicado en 2007

Effects of tetraalkylammonium compounds with different affinities for organic cation transporters on the pharmacokinetics of metformin

artículo científico publicado en 2007

Efficacy of a new sustained-release microsphere formulation of exenatide, DA-3091, in Zucker diabetic fatty (ZDF) rats

artículo científico publicado en 2010

Enhanced electrostatic interaction between chitosan-modified PLGA nanoparticle and tumor

artículo científico publicado en 2008

Enhanced intestinal absorption of salmon calcitonin (sCT) from proliposomes containing bile salts

artículo científico publicado en 2005

Enhanced intracellular accumulation of a non-nucleoside anti-cancer agent via increased uptake of its valine ester prodrug through amino acid transporters ⬇️

artículo científico publicado el 10 de enero de 2012

Enhanced oral bioavailability of paclitaxel by coadministration of the P-glycoprotein inhibitor KR30031.

artículo científico publicado en 2003

Enhanced solubility and stability of PEGylated liposomal paclitaxel: in vitro and in vivo evaluation

artículo científico publicado en 2007

Enhancedin vitrocellular uptake of P-gp substrate by poloxamer-modified liposomes (PMLs) in MDR cancer cells ⬇️

artículo científico publicado el 19 de julio de 2011

Enhancement of paracellular transport of heparin disaccharide across Caco-2 cell monolayers

artículo científico publicado en 2002

Enhancing effect of surfactants on fexofenadine.HCl transport across the human nasal epithelial cell monolayer

artículo científico publicado en 2006

Evaluation of protein stability and in vitro permeation of lyophilized polysaccharides-based microparticles for intranasal protein delivery

artículo científico publicado en 2011

Evidence of carrier-mediated transport in the penetration of donepezil into the rat brain

artículo científico publicado en 2010

Expression and functional activity of P-glycoprotein in passaged primary human nasal epithelial cell monolayers cultured by the air–liquid interface method for nasal drug transport study ⬇️

artículo científico publicado el 8 de febrero de 2011

Fluorescence Detection of Zabofloxacin, a Novel Fluoroquinolone Antibiotic, in Plasma, Bile, and Urine by HPLC: The First Oral and Intravenous Applications in a Pharmacokinetic Study in Rats ⬇️

artículo científico publicado el 1 de enero de 2011

Functional Consequences of Genetic Variations in the Human Organic Anion Transporting Polypeptide 1B3 (OATP1B3) in the Korean Population ⬇️

artículo científico publicado el 6 de diciembre de 2011

Functional impairment of rat taurine transporter by activation of nitrogen oxide through superoxide

artículo científico publicado en 2011

Functional induction of P-glycoprotein in the blood-brain barrier of streptozotocin-induced diabetic rats: evidence for the involvement of nuclear factor-kappaB, a nitrosative stress-sensitive transcription factor, in the regulation

artículo científico

Hepatobiliary excretion of tributylmethylamonium in rats with lipopolysaccharide-induced acute inflammation

artículo científico publicado en 2002

Hyaluronic acid complexed to biodegradable poly L-arginine for targeted delivery of siRNAs

artículo científico publicado en 2009

Hyaluronic acid derivative-based self-assembled nanoparticles for the treatment of melanoma

artículo científico publicado en 2012

Identification of genes enhanced by protein-calorie malnutrition by differential display polymerase chain reaction (expression of fibrinogen B beta chain, B cell translocation gene 1 and thyroid hormone responsive protein genes)

scientific journal article

Identification of metabolites of MDR-1339, an inhibitor of β-amyloid protein aggregation, and kinetic characterization of the major metabolites in rats.

artículo científico publicado en 2018

In vitro and in vivo evaluation of N,N,N-trimethylphytosphingosine-iodide (TMP) in liposomes for the treatment of angiogenesis and metastasis.

artículo científico publicado en 2012

In vitro and in vivo evaluation of a novel nonscrotal matrix-type transdermal delivery system of testosterone

artículo científico publicado en 2005

Increased affinity to canalicular P-gp via formation of lipophilic ion-pair complexes with endogenous bile salts is associated with mw threshold in hepatobiliary excretion of quaternary ammonium compounds

artículo científico publicado en 2010

Inhibition effect of flavonoids on monocarboxylate transporter 1 (MCT1) in Caco-2 cells

artículo científico publicado en 2007

Investigation into the Efficacy of Val-SN-38, a Valine-Ester Prodrug of the Anti-Cancer Agent SN-38.

artículo científico publicado en 2012

Involvement of P-glycoprotein, multidrug resistance protein 2 and breast cancer resistance protein in the transport of belotecan and topotecan in Caco-2 and MDCKII cells

artículo científico publicado en 2008

Kinetic analysis about the bidirectional transport of 1-anilino-8-naphthalene sulfonate (ANS) by isolated rat hepatocytes ⬇️

artículo científico publicado el 1 de abril de 2003

Lack of a primary physicochemical determinant in the direct transport of drugs to the brain after nasal administration in rats: potential involvement of transporters in the pathway

artículo científico publicado en 2010

Limited role of P-glycoprotein in the intestinal absorption of cyclosporin A.

artículo científico publicado en 2005

Liposome formulation of paclitaxel with enhanced solubility and stability

artículo científico publicado en 2007

Liver Cancer Targeting of Doxorubicin with Reduced Distribution to the Heart Using Hematoporphyrin-Modified Albumin Nanoparticles in Rats ⬇️

artículo científico publicado el 5 de octubre de 2011

Long-term administration of an aqueous extract of dried, immature fruit of Poncirus trifoliata (L.) Raf. suppresses body weight gain in rats

artículo científico publicado en 2009

Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates

artículo científico publicado en 2009

Mechanism of intestinal transport of an organic cation, tributylmethylammonium in Caco-2 cell monolayers

artículo científico

Mechanism of the reduced elimination clearance of benzylpenicillin from cerebrospinal fluid in rats with intracisternal administration of lipopolysaccharide

artículo científico publicado en 2002

Mechanism of the stationary canalicular excretion of tributylmethyl ammonium in rats with a CCl4-induced acute hepatic injury

artículo científico publicado en 2005

Modulation of biodistribution and expression of plasmid DNA following mesenchymal progenitor cell-based delivery

scientific article published on 01 June 2008

Multifunctional doxorubicin loaded superparamagnetic iron oxide nanoparticles for chemotherapy and magnetic resonance imaging in liver cancer

artículo científico publicado en 2010

Multiple alterations of canalicular membrane transport activities in rats with CCl(4)-induced hepatic injury

artículo científico publicado en 2003

Novel porous matrix of hyaluronic acid for the three-dimensional culture of chondrocytes

artículo científico publicado en 2008

Opsonized erythrocyte ghosts for liver-targeted delivery of antisense oligodeoxynucleotides

artículo científico publicado en 2008

P-glycoprotein-mediated transport of berberine across Caco-2 cell monolayers

artículo científico publicado en 2002

Paracellular permeation-enhancing effect of AT1002 C-terminal amidation in nasal delivery

artículo científico publicado en 2015

Pharmacokinetic characterization of dehydroevodiamine in the rat brain

artículo científico publicado en 2004

Pharmacokinetics and efficacy of a biweekly dosage formulation of exenatide in Zucker diabetic fatty (ZDF) rats

artículo científico publicado en 2009

Pharmacokinetics and first-pass elimination of metoprolol in rats: contribution of intestinal first-pass extraction to low bioavailability of metoprolol

artículo científico publicado en 2010

Pharmacokinetics and pharmacodynamics of ketoprofen plasters

artículo científico publicado en 2008

Physiologically based pharmacokinetic modeling of SNU-0039, an anti-Alzheimer's agent, in rats

artículo científico publicado en 2011

Poloxamer/cyclodextrin/chitosan-based thermoreversible gel for intranasal delivery of fexofenadine hydrochloride.

artículo científico publicado en 2010

Poly-L-arginine and Dextran Sulfate-Based Nanocomplex for Epidermal Growth Factor Receptor (EGFR) siRNA Delivery: Its Application for Head and Neck Cancer Treatment ⬇️

artículo científico publicado el 15 de diciembre de 2011

Porous hyaluronic acid/sodium alginate composite scaffolds for human adipose-derived stem cells delivery.

artículo científico publicado en 2013

Preparation and evaluation of fexofenadine microemulsion for intranasal delivery

Preparation and evaluation of fexofenadine microemulsions for intranasal delivery

artículo científico publicado en 2010

Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposome

artículo científico publicado en 2007

Preparation and evaluation of proliposomes containing salmon calcitonin

artículo científico publicado en 2002

Preparation and evaluation of spray-dried hyaluronic acid microspheres for intranasal delivery of fexofenadine hydrochloride

artículo científico publicado en 2010

Preparation, characterization and in vitro intestinal absorption of a dry emulsion formulation containing atorvastatin calcium.

artículo científico publicado en 2009

Prokinetic activity of an aqueous extract from dried immature fruit of Poncirus trifoliata (L.) Raf.

artículo científico publicado en 2005

Proliferation and chondrogenic differentiation of human adipose-derived mesenchymal stem cells in porous hyaluronic acid scaffold ⬇️

artículo científico publicado el 30 de julio de 2011

Proliposomes as an intranasal dosage form for the sustained delivery of propranolol

artículo científico publicado en 1995

Quantification of CKD-501, lobeglitazone, in rat plasma using a liquid-chromatography/tandem mass spectrometry method and its applications to pharmacokinetic studies

artículo científico publicado en 2009

Quantification of clotiazepam in human plasma by gas chromatography-mass spectrometry.

artículo científico publicado en 2006

Rapid and sensitive determination of udenafil in plasma by LC-MS/MS for intranasal pharmacokinetic study in rats

artículo científico publicado en 2011

Reduced antidiabetic effect of metformin and down-regulation of hepatic Oct1 in rats with ethynylestradiol-induced cholestasis

artículo científico publicado en 2008

Saturable distribution of tacrine into the striatal extracellular fluid of the rat: evidence of involvement of multiple organic cation transporters in the transport

artículo científico publicado en 2004

Saturable sinusoidal uptake is rate-determining process in hepatic elimination of docetaxel in rats

scientific article published on 02 July 2012

Simple liquid chromatography-electrospray ionization mass spectrometry method for the routine determination of salmon calcitonin in serum

artículo científico publicado en 2002

Simultaneous Determination of Artesunate and Dihydroartemisinin Concentrations in Human Plasma by High Performance Liquid Chromatography-Mass Spectrometry with Electro-Spray Ionization

article by Kyeong-Ryoon Lee et al published 12 January 2010 in Analytical Letters

Skin permeation enhancement of diclofenac by fatty acids

artículo científico publicado en 2008

Small intestinal transit does not adequately represent postoperative paralytic ileus in rats

artículo científico publicado en 2002

Smooth muscle relaxation activity of an aqueous extract of dried immature fruit of Poncirus trifoliata (PF-W) on an isolated strip of rat ileum.

artículo científico publicado en 2013

Synergic enhancing-effect of DEET and dodecylamine on the skin permeation of testosterone from a matrix-type transdermal delivery system.

artículo científico publicado en 2009

Testosterone-independent down-regulation of Oct2 in the kidney medulla from a uranyl nitrate-induced rat model of acute renal failure: effects on distribution of a model organic cation, tetraethylammonium

artículo científico publicado en 2009

The effects of mixed MPEG-PLA/Pluronic copolymer micelles on the bioavailability and multidrug resistance of docetaxel

artículo científico publicado en 2010

The limited intestinal absorption via paracellular pathway is responsible for the low oral bioavailability of doxorubicin

scientific article published on 19 December 2012

The suppressed expression and functional activity of hepatic P-glycoprotein in rats with protein-calorie malnutrition

artículo científico publicado en 2003

The transport of organic cations in the small intestine: current knowledge and emerging concepts

artículo científico publicado en 2006

Transfection of primary human nasal epithelial cells using a biodegradable poly (ester amine) based on polycaprolactone and polyethylenimine as a gene carrier

artículo científico publicado en 2007

Transient aggregation of chitosan-modified poly(d,l-lactic-co-glycolic) acid nanoparticles in the blood stream and improved lung targeting efficiency.

artículo científico publicado en 2016

Transport of anti-allergic drugs across the passage cultured human nasal epithelial cell monolayer

artículo científico publicado en 2005

Transport of gemifloxacin, a 4th generation quinolone antibiotic, in the Caco-2 and engineered MDCKII cells, and potential involvement of efflux transporters in the intestinal absorption of the drug

artículo científico publicado en 2012

Ursodeoxycholate Restores Biliary Excretion of Methotrexate in Rats with Ethinyl Estradiol Induced-Cholestasis by Restoring Canalicular Mrp2 Expression.

artículo científico publicado en 2018

[Study on the history of exchange in pharmaceutical science between Japan and Korea after the Modern period: focus on Korean students sent to Japan with expenses funded by the Japanese government]

artículo científico publicado en 2009

[The history of pharmacy in Korea]

artículo científico publicado en 2008

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