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A correlation of endocrine and anticancer effects of some antagonists of GHRH.

artículo científico publicado en 2010

Antagonists of growth hormone-releasing hormone (GHRH) reduce prostate size in experimental benign prostatic hyperplasia

artículo científico publicado en 2011

Antagonists of growth hormone-releasing hormone inhibit growth of androgen-independent prostate cancer through inactivation of ERK and Akt kinases

artículo científico publicado en 2012

Beneficial effects of novel antagonists of GHRH in different models of Alzheimer's disease

artículo científico publicado en 2012

Combination of gastrin-releasing peptide antagonist with cytotoxic agents produces synergistic inhibition of growth of human experimental colon cancers

artículo científico publicado en 2012

Combining growth hormone-releasing hormone antagonist with luteinizing hormone-releasing hormone antagonist greatly augments benign prostatic hyperplasia shrinkage

artículo científico publicado en 2012

GHRH antagonist causes DNA damage leading to p21 mediated cell cycle arrest and apoptosis in human colon cancer cells

artículo científico publicado en 2009

GHRH antagonist when combined with cytotoxic agents induces S-phase arrest and additive growth inhibition of human colon cancer

artículo científico publicado en 2012

Hormonal manipulation of benign prostatic hyperplasia

artículo científico

Inhibition of U-87 MG glioblastoma by AN-152 (AEZS-108), a targeted cytotoxic analog of luteinizing hormone-releasing hormone

artículo científico publicado en 2013

Inhibition of human non-small cell lung cancers with a targeted cytotoxic somatostatin analog, AN-162.

artículo científico publicado en 2009

Inhibitory effects of GHRH antagonists on human GH-secreting adenoma tissue

artículo científico publicado en 2012

LHRH antagonist Cetrorelix reduces prostate size and gene expression of proinflammatory cytokines and growth factors in a rat model of benign prostatic hyperplasia

artículo científico publicado en 2010

Mechanisms of synergism between antagonists of growth hormone-releasing hormone and antagonists of luteinizing hormone-releasing hormone in shrinking experimental benign prostatic hyperplasia

artículo científico publicado en 2012

New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor

artículo científico publicado en 2015

Novel GHRH antagonists suppress the growth of human malignant melanoma by restoring nuclear p27 function.

artículo científico publicado en 2014

Novel antagonists of growth hormone-releasing hormone inhibit growth and vascularization of human experimental ovarian cancers

artículo científico publicado en 2011

Potentiation of cytotoxic chemotherapy by growth hormone-releasing hormone agonists

artículo científico publicado en 2013

Powerful inhibition of experimental human pancreatic cancers by receptor targeted cytotoxic LH-RH analog AEZS-108.

artículo científico publicado en 2013

Powerful inhibition of in-vivo growth of experimental hepatic cancers by bombesin/gastrin-releasing peptide antagonist RC-3940-II.

artículo científico publicado en 2012

Preclinical evaluation of properties of a new targeted cytotoxic somatostatin analog, AN-162 (AEZS-124), and its effects on tumor growth inhibition

artículo científico publicado en 2009

Receptor-targeted therapy of human experimental urinary bladder cancers with cytotoxic LH-RH analog AN-152 (AEZS-108)

artículo científico publicado el 1 de julio de 2012

Shrinkage of experimental benign prostatic hyperplasia and reduction of prostatic cell volume by a gastrin-releasing peptide antagonist

artículo científico publicado en 2013

Suppression of the proliferation of human U-87 MG glioblastoma cells by new antagonists of growth hormone-releasing hormone in vivo and in vitro.

artículo científico publicado en 2013

Synthesis and structure-activity studies on novel analogs of human growth hormone releasing hormone (GHRH) with enhanced inhibitory activities on tumor growth

artículo científico publicado en 2017

Synthesis of new potent agonistic analogs of growth hormone-releasing hormone (GHRH) and evaluation of their endocrine and cardiac activities

artículo científico publicado en 2013

Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels.

artículo científico publicado en 2014

Targeted cytotoxic somatostatin analog AN-162 inhibits growth of human colon carcinomas and increases sensitivity of doxorubicin resistant murine leukemia cells.

artículo científico publicado en 2010

Targeting triple-negative breast cancer through the somatostatin receptor with the new cytotoxic somatostatin analogue AN-162 [AEZS-124].

artículo científico publicado en 2013

Triple negative breast cancers express receptors for LHRH and are potential therapeutic targets for cytotoxic LHRH-analogs, AEZS 108 and AEZS 125

artículo científico publicado en 2014

Triple-negative breast cancers express receptors for luteinizing hormone-releasing hormone (LHRH) and respond to LHRH antagonist cetrorelix with growth inhibition

artículo científico publicado en 2009