Lista de obras -

A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration

artículo científico publicado en 2006

A possible link between astrocyte activation and tau nitration in Alzheimer's disease.

scientific article published on 02 May 2008

Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease

artículo científico publicado en 2008

Active c-jun N-terminal kinase induces caspase cleavage of tau and additional phosphorylation by GSK-3beta is required for tau aggregation

artículo científico publicado en 2008

Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy

artículo científico publicado en 2008

Alterations in the nuclear architecture produced by the overexpression of tau protein in neuroblastoma cells.

artículo científico publicado en 2013

Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system.

artículo científico

Axonal transport defects in neurodegenerative diseases

scientific article published on October 2009

Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis

artículo científico publicado en 2007

C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease

artículo científico publicado en 2000

Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases

artículo científico publicado en 2000

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

artículo científico publicado en 2003

Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease.

artículo científico publicado en 2011

Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease

artículo científico publicado en 2008

Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology

artículo científico publicado en 2007

Conformational changes and truncation of tau protein during tangle evolution in Alzheimer's disease.

artículo científico publicado en 2003

Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro

artículo científico publicado en 2006

Differential assembly of human tau isoforms in the presence of arachidonic acid

artículo científico publicado en 2000

Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.

artículo científico publicado en 2004

Formation of phospho-SAPK/JNK granules in the hippocampus is an early event in Alzheimer disease

artículo científico publicado en 2006

Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.

artículo científico publicado en 2011

Hippocampal plasticity during the progression of Alzheimer's disease

artículo científico publicado en 2015

Hsp70 Alters Tau Function and Aggregation in an Isoform Specific Manner ⬇️

artículo científico publicado el 23 de enero de 2012

In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants

artículo científico publicado en 2000

Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment

artículo científico publicado en 2003

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody.

artículo científico publicado en 2012

Ligand-dependent tau filament formation: implications for Alzheimer's disease progression

artículo científico publicado en 1999

Mild cognitive impairment: pathology and mechanisms.

artículo científico publicado en 2011

Modeling tau polymerization in vitro: a review and synthesis

artículo científico publicado en 2003

N-terminal fragments of tau inhibit full-length tau polymerization in vitro

scientific article published on 01 October 2006

Nitration in neurodegeneration: deciphering the "Hows" "nYs".

artículo científico publicado en 2007

Oxidative regulation of fatty acid-induced tau polymerization

artículo científico publicado en 2000

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases ⬇️

artículo científico publicado el 6 de julio de 2011

Pathological glial tau accumulations in neurodegenerative disease: review and case report

artículo científico publicado en 2001

Peroxynitrite-induced nitrative and oxidative modifications alter tau filament formation.

artículo científico publicado en 2011

Peroxynitrite-mediated tau modifications stabilize preformed filaments and destabilize microtubules through distinct mechanisms

artículo científico publicado en 2006

Phosphorylation and cleavage of tau in non-AD tauopathies.

artículo científico publicado en 2007

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.

artículo científico publicado en 2011

Prefibrillar tau oligomers in mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2013

Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2011

Proline Isomer-Specific Antibodies Reveal the Early Pathogenic Tau Conformation in Alzheimer's Disease ⬇️

artículo científico publicado el 30 de marzo de 2012

Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease

artículo científico publicado en 2016

Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease.

artículo científico publicado en 2013

Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo.

artículo científico publicado en 2006

Relation of hippocampal phospho-SAPK/JNK granules in Alzheimer's disease and tauopathies to granulovacuolar degeneration bodies

artículo científico publicado en 2006

Selective tau tyrosine nitration in non-AD tauopathies ⬇️

artículo científico publicado el 6 de noviembre de 2011

Site-specific nitration and oxidative dityrosine bridging of the tau protein by peroxynitrite: implications for Alzheimer's disease

artículo científico publicado en 2005

Site-specific nitration differentially influences tau assembly in vitro

artículo científico publicado en 2005

Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis

artículo científico publicado en 2010

TOC1: a valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy.

artículo científico publicado en 2014

TOC1: characterization of a selective oligomeric tau antibody

artículo científico publicado en 2013

Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro

artículo científico publicado en 2009

Tau as a therapeutic target in neurodegenerative disease ⬇️

artículo científico publicado el 10 de julio de 2012

Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2002

Tau epitope display in progressive supranuclear palsy and corticobasal degeneration

artículo científico publicado en 2004

Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies.

artículo científico publicado en 2006

Tau oligomers and tau toxicity in neurodegenerative disease ⬇️

artículo científico publicado el 1 de agosto de 2012

Tau oligomers as potential targets for early diagnosis of tauopathy

artículo científico publicado en 2014

Tau polymerization: role of the amino terminus

artículo científico publicado en 2003

Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease.

artículo científico publicado en 2004

Tau, tangles, and Alzheimer's disease

artículo científico publicado en 2005

Tau-66: evidence for a novel tau conformation in Alzheimer's disease

artículo científico publicado en 2001

The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy

artículo científico publicado en 2003

The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.

artículo científico publicado en 2009

The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology

artículo científico publicado en 1996

Tyrosine nitration within the proline-rich region of Tau in Alzheimer's disease

artículo científico publicado en 2011

Ubiquitin is Associated with Early Truncation of Tau Protein at Aspartic Acid421 during the Maturation of Neurofibrillary Tangles in Alzheimer's Disease ⬇️

artículo científico publicado el 12 de octubre de 2011

X-ray diffraction from intact tau aggregates in human brain tissue ⬇️

artículo científico publicado el 1 de septiembre de 2011

Lista de obras de

A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration

A possible link between astrocyte activation and tau nitration in Alzheimer's disease.

Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease

Active c-jun N-terminal kinase induces caspase cleavage of tau and additional phosphorylation by GSK-3beta is required for tau aggregation

Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy

Alterations in the nuclear architecture produced by the overexpression of tau protein in neuroblastoma cells.

Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system.

Axonal transport defects in neurodegenerative diseases

Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis

C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease

Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease.

Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease

Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology

Conformational changes and truncation of tau protein during tangle evolution in Alzheimer's disease.

Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro

Differential assembly of human tau isoforms in the presence of arachidonic acid

Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.

Formation of phospho-SAPK/JNK granules in the hippocampus is an early event in Alzheimer disease

Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.

Hippocampal plasticity during the progression of Alzheimer's disease

Hsp70 Alters Tau Function and Aggregation in an Isoform Specific Manner ⬇️

In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants

Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody.

Ligand-dependent tau filament formation: implications for Alzheimer's disease progression

Mild cognitive impairment: pathology and mechanisms.

Modeling tau polymerization in vitro: a review and synthesis

N-terminal fragments of tau inhibit full-length tau polymerization in vitro

Nitration in neurodegeneration: deciphering the "Hows" "nYs".

Oxidative regulation of fatty acid-induced tau polymerization

Pathogenic Forms of Tau Inhibit Kinesin-Dependent Axonal Transport through a Mechanism Involving Activation of Axonal Phosphotransferases ⬇️

Pathological glial tau accumulations in neurodegenerative disease: review and case report

Peroxynitrite-induced nitrative and oxidative modifications alter tau filament formation.

Peroxynitrite-mediated tau modifications stabilize preformed filaments and destabilize microtubules through distinct mechanisms

Phosphorylation and cleavage of tau in non-AD tauopathies.

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.

Prefibrillar tau oligomers in mild cognitive impairment and Alzheimer's disease

Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease

Proline Isomer-Specific Antibodies Reveal the Early Pathogenic Tau Conformation in Alzheimer's Disease ⬇️

Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease

Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease.

Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo.

Relation of hippocampal phospho-SAPK/JNK granules in Alzheimer's disease and tauopathies to granulovacuolar degeneration bodies

Selective tau tyrosine nitration in non-AD tauopathies ⬇️

Site-specific nitration and oxidative dityrosine bridging of the tau protein by peroxynitrite: implications for Alzheimer's disease

Site-specific nitration differentially influences tau assembly in vitro

Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis

TOC1: a valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy.

TOC1: characterization of a selective oligomeric tau antibody

Tau 6D and 6P isoforms inhibit polymerization of full-length tau in vitro

Tau as a therapeutic target in neurodegenerative disease ⬇️

Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease

Tau epitope display in progressive supranuclear palsy and corticobasal degeneration

Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies.

Tau oligomers and tau toxicity in neurodegenerative disease ⬇️

Tau oligomers as potential targets for early diagnosis of tauopathy

Tau polymerization: role of the amino terminus

Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease.

Tau, tangles, and Alzheimer's disease

Tau-66: evidence for a novel tau conformation in Alzheimer's disease

The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy

The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.

The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology

Tyrosine nitration within the proline-rich region of Tau in Alzheimer's disease

Ubiquitin is Associated with Early Truncation of Tau Protein at Aspartic Acid421 during the Maturation of Neurofibrillary Tangles in Alzheimer's Disease ⬇️

X-ray diffraction from intact tau aggregates in human brain tissue ⬇️