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Activating mutations in ALK kinase domain confer resistance to structurally unrelated ALK inhibitors in NPM-ALK-positive anaplastic large-cell lymphoma

artículo científico publicado en 2014

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase

scientific article published on 24 April 2020

Comprehensive analysis of the palindromic motif TCTCGCGAGA: a regulatory element of the HNRNPK promoter

artículo científico publicado en 2010

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases

scientific article published on 23 July 2019

Differences in gene expression and alterations in cell cycle of acute myeloid leukemia cell lines after treatment with JAK inhibitors

artículo científico publicado en 2015

Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors

scientific article published on 13 March 2020

Discovery and optimization of novel pyrazole-benzimidazole CPL304110, as a potent and selective inhibitor of fibroblast growth factor receptors FGFR (1-3)

artículo científico publicado en 2020

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis

artículo científico publicado en 2020

Discovery of TRAF-2 and NCK-interacting kinase (TNIK) inhibitors by ligand-based virtual screening methods

Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase

artículo científico publicado en 2017

Epithelial-mesenchymal transition confers resistance to selective FGFR inhibitors in SNU-16 gastric cancer cells

artículo científico publicado en 2014

NG2 expressing cells in hippocampal cultures survive neurotoxic insult and retain the ability to divide.

artículo científico publicado en 2005

TNFalpha and TNF receptor 1 expression in the mixed neuronal-glial cultures of hippocampal dentate gyrus exposed to glutamate or trimethyltin

artículo científico publicado en 2006

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma

artículo científico publicado en 2017

The ameboid phenotype of NG2 (+) cells in the region of apoptotic dentate granule neurons in trimethyltin intoxicated mice shares antigen properties with microglia/macrophages

scientific article published on 01 January 2008

Trimethyltin-evoked apoptosis of murine hippocampal granule neurons is accompanied by the expression of interleukin-1beta and interleukin-1 receptor antagonist in cells of ameboid phenotype, the majority of which are NG2-positive

artículo científico publicado en 2008

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