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2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture.

artículo científico publicado en 2017

Approaches to hepatitis C treatment and cure using NS5A inhibitors

scientific article published on 05 March 2014

Biochemical Characterization of the Active Anti-Hepatitis C Virus Metabolites of 2,6-Diaminopurine Ribonucleoside Prodrug Compared to Sofosbuvir and BMS-986094.

artículo científico publicado en 2016

Characterization of β-d-N4-Hydroxycytidine as a Novel Inhibitor of Chikungunya Virus

artículo científico publicado en 2017

Chutes and ladders in hepatitis C nucleoside drug development

artículo científico publicado en 2014

Discovery of a Series of 2'-α-Fluoro,2'-β-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus

artículo científico publicado en 2019

Discovery, characterization, and lead optimization of 7-azaindole non-nucleoside HIV-1 reverse transcriptase inhibitors

artículo científico publicado en 2016

Metabolism of Nucleosides and Nucleotides Prodrugs

artículo científico publicado en 2017

Nucleotide Substrate Specificity of Anti-Hepatitis C Virus Nucleoside Analogs for Human Mitochondrial RNA Polymerase

artículo científico publicado en 2017

Synthesis and Evaluation of 2,6-Modified Purine 2'-C-Methyl Ribonucleosides as Inhibitors of HCV Replication

artículo científico publicado en 2015

Toward Elimination of Hepatitis B Virus Using Novel Drugs, Approaches, and Combined Modalities

artículo científico publicado en 2016

Towards HBV curative therapies

artículo científico publicado en 2018

β-D-2'-C-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5'-Triphosphate Forms

artículo científico publicado en 2015

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