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Delayed chain termination protects the anti-hepatitis B virus drug entecavir from excision by HIV-1 reverse transcriptase

artículo científico publicado en 2008

Engineering of a chimeric RB69 DNA polymerase sensitive to drugs targeting the cytomegalovirus enzyme

artículo científico publicado en 2009

Evaluation of single and combination therapies with tenofovir disoproxil fumarate and emtricitabine in vitro and in a robust mouse model supporting high levels of hepatitis B virus replication

artículo científico publicado en 2012

Mechanism of Activation of -D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

artículo científico publicado en 2007

Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase

scientific article published on 09 June 2009

Pharmacokinetics of the anti-human immunodeficiency virus agent 1-(beta-D-dioxolane)thymine in rhesus monkeys

artículo científico publicado en 2007

Short communication cellular pharmacology of 9-(beta-D-1,3-dioxolan-4-yl) guanine and its lack of drug interactions with zidovudine in primary human lymphocytes

artículo científico publicado en 2007

Simultaneous quantification of 9-(beta-D-1,3-dioxolan-4-yl)guanine, Amdoxovir and Zidovudine in human plasma by liquid chromatography-tandem mass spectrometric assay

artículo científico publicado en 2009

Simultaneous quantification of intracellular natural and antiretroviral nucleosides and nucleotides by liquid chromatography-tandem mass spectrometry

artículo científico

Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs

artículo científico publicado el 13 de septiembre de 2011

Synthesis and Anti-HIV Evaluation of 3′-Triazolo Nucleosides

artículo científico publicado el 1 de abril de 2011

Synthesis and evaluation of 3'-azido-2',3'-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus

artículo científico publicado en 2009

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3′-azido-2′,3′-dideoxypurine nucleosides

artículo científico publicado el 30 de mayo de 2011

Telbivudine exerts no antiviral activity against HIV-1 in vitro and in humans.

artículo científico publicado en 2011