Lista de obras -

A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients

artículo científico publicado en 2009

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

artículo científico publicado en 2007

Angiogenesis in brain tumours

artículo científico publicado en 2007

Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors.

artículo científico publicado en 2010

Antiangiogenic agents for the treatment of glioblastoma

scientific article published on December 2007

Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: theory and clinical practice

artículo científico publicado en 2006

Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer

artículo científico publicado en 2007

Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy

artículo científico publicado en 2006

Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer

artículo científico publicado en 2009

Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer

artículo científico publicado en 2004

Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice

artículo científico publicado en 2009

Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study

artículo científico publicado en 2009

Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study

artículo científico publicado en 2009

Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosis ⬇️

artículo científico publicado el 11 de agosto de 2011

Exploratory analysis of early toxicity of sunitinib in advanced hepatocellular carcinoma patients: kinetics and potential biomarker value.

artículo científico publicado en 2010

Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape

artículo científico publicado en 2011

Hearing improvement after bevacizumab in patients with neurofibromatosis type 2

artículo científico publicado en 2009

Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications

artículo científico publicado en 2006

In vivo validation of MRI vessel caliber index measurement methods with intravital optical microscopy in a U87 mouse brain tumor model

artículo científico publicado en 2010

Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

artículo científico publicado en 2004

Lymphatic metastasis in the absence of functional intratumor lymphatics

artículo científico publicado en 2002

Merlin/NF2 Regulates Angiogenesis in Schwannomas through a Rac1/Semaphorin 3F-Dependent Mechanism ⬇️

artículo científico publicado el 1 de febrero de 2012

Mosaic tumor vessels: cellular basis and ultrastructure of focal regions lacking endothelial cell markers

artículo científico publicado en 2005

PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment

artículo científico publicado en 2009

Pathology: cancer cells compress intratumour vessels.

artículo científico publicado en 2004

Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma

artículo científico publicado en 2010

Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer

artículo científico publicado en 2010

Platelet-derived growth factor receptor-beta in Gorham's disease

artículo científico publicado en 2006

Responses to antiangiogenesis treatment of spontaneous autochthonous tumors and their isografts

scientific article published on 01 February 2003

Robust 3-D modeling of vasculature imagery using superellipsoids

artículo científico publicado en 2007

Safety, Efficacy, and Biomarker Exploration in a Phase II Study of Bevacizumab, Oxaliplatin, and Gemcitabine in Recurrent Müllerian Carcinoma ⬇️

artículo científico publicado el 1 de junio de 2011

Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients

artículo científico publicado en 2005

Tumour biology: herceptin acts as an anti-angiogenic cocktail.

artículo científico publicado en 2002

VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer

artículo científico publicado en 2009

p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis

artículo científico publicado en 2009

Lista de obras de

A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients

AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

Angiogenesis in brain tumours

Anti-vascular endothelial growth factor therapies as a novel therapeutic approach to treating neurofibromatosis-related tumors.

Antiangiogenic agents for the treatment of glioblastoma

Combined vascular endothelial growth factor-targeted therapy and radiotherapy for rectal cancer: theory and clinical practice

Complete pathological response to bevacizumab and chemoradiation in advanced rectal cancer

Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy

Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer

Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer

Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice

Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study

Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study

Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosis ⬇️

Exploratory analysis of early toxicity of sunitinib in advanced hepatocellular carcinoma patients: kinetics and potential biomarker value.

Glioblastoma recurrence after cediranib therapy in patients: lack of "rebound" revascularization as mode of escape

Hearing improvement after bevacizumab in patients with neurofibromatosis type 2

Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications

In vivo validation of MRI vessel caliber index measurement methods with intravital optical microscopy in a U87 mouse brain tumor model

Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

Lymphatic metastasis in the absence of functional intratumor lymphatics

Merlin/NF2 Regulates Angiogenesis in Schwannomas through a Rac1/Semaphorin 3F-Dependent Mechanism ⬇️

Mosaic tumor vessels: cellular basis and ultrastructure of focal regions lacking endothelial cell markers

PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment

Pathology: cancer cells compress intratumour vessels.

Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma

Plasma soluble VEGFR-1 is a potential dual biomarker of response and toxicity for bevacizumab with chemoradiation in locally advanced rectal cancer

Platelet-derived growth factor receptor-beta in Gorham's disease

Responses to antiangiogenesis treatment of spontaneous autochthonous tumors and their isografts

Robust 3-D modeling of vasculature imagery using superellipsoids

Safety, Efficacy, and Biomarker Exploration in a Phase II Study of Bevacizumab, Oxaliplatin, and Gemcitabine in Recurrent Müllerian Carcinoma ⬇️

Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients

Tumour biology: herceptin acts as an anti-angiogenic cocktail.

VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer

p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis