Lista de obras -

A minimal isoform of the TMEM16A protein associated with chloride channel activity.

artículo científico publicado en 2011

A quantitative description of the activation and inhibition of CFTR by potentiators: Genistein.

artículo científico publicado en 2005

Alpha-aminoazaheterocyclic-methylglyoxal adducts do not inhibit cystic fibrosis transmembrane conductance regulator chloride channel activity.

artículo científico publicado en 2008

Altered channel gating mechanism for CFTR inhibition by a high-affinity thiazolidinone blocker

artículo científico publicado en 2004

Antihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations.

artículo científico publicado en 2005

Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia.

artículo científico publicado en 2012

Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins.

artículo científico publicado en 2007

CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds

artículo científico publicado en 2003

CFTR pharmacology.

artículo científico publicado en 2016

Ca2+-activated Cl- channels

artículo científico

Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.

artículo científico publicado en 2002

Direct interaction of a CFTR potentiator and a CFTR corrector with phospholipid bilayers

artículo científico publicado en 2014

Double mechanism for apical tryptophan depletion in polarized human bronchial epithelium

artículo científico publicado en 2004

Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations.

artículo científico publicado en 2011

Effect of inflammatory stimuli on airway ion transport.

artículo científico publicado en 2004

Epithelial sodium channel inhibition in primary human bronchial epithelia by transfected siRNA.

artículo científico publicado en 2008

Epithelial sodium channel silencing as a strategy to correct the airway surface fluid deficit in cystic fibrosis

artículo científico publicado en 2013

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel

artículo científico publicado en 2016

Evidence for direct CFTR inhibition by CFTR(inh)-172 based on Arg347 mutagenesis.

artículo científico publicado en 2008

Functional analysis of acid-activated Cl⁻ channels: properties and mechanisms of regulation.

artículo científico publicado en 2015

Functional and pharmacological induced structural changes of the cystic fibrosis transmembrane conductance regulator in the membrane solved using SAXS.

artículo científico publicado en 2014

Functional human CFTR produced by a stable minichromosome

artículo científico publicado en 2002

Gelsolin Secretion in Interleukin-4–treated Bronchial Epithelia and in Asthmatic Airways

artículo científico publicado en 2005

High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening

artículo científico publicado en 2002

High-throughput screening of libraries of compounds to identify CFTR modulators.

artículo científico publicado en 2011

IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro

artículo científico publicado en 2002

In vitro recapitulation of the site-specific editing (to wild-type) of mutant IDS mRNA transcripts, and the characterization of IDS protein translated from the edited mRNAs

artículo científico publicado en 2017

Lectin conjugates as potent, nonabsorbable CFTR inhibitors for reducing intestinal fluid secretion in cholera.

artículo científico publicado en 2007

Modulation of cystic fibrosis transmembrane conductance regulator (CFTR) activity and genistein binding by cytosolic pH.

artículo científico publicado en 2010

Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators.

artículo científico publicado en 2009

Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides

artículo científico publicado en 2008

On the measurement of the functional properties of the CFTR.

artículo científico publicado en 2008

Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways.

artículo científico publicado en 2016

Pharmacological rescue of mutant CFTR protein improves the viscoelastic properties of CF mucus.

artículo científico publicado en 2015

Pharmacological therapy for cystic fibrosis: from bench to bedside

artículo científico publicado en 2011

Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating

artículo científico publicado en 2005

Proteomic analysis of the airway surface liquid: modulation by proinflammatory cytokines

article

Regulation of TMEM16A chloride channel properties by alternative splicing

artículo científico publicado en 2009

Rheological Properties of Cystic Fibrosis Bronchial Secretion and in Vitro Drug Permeation Study: The Effect of Sodium Bicarbonate

artículo científico publicado en 2016

Small molecule anionophores promote transmembrane anion permeation matching CFTR activity

artículo científico publicado en 2018

Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.

artículo científico publicado en 2005

Structure of wild type and mutant F508del CFTR: A small-angle X-ray scattering study of the protein-detergent complexes.

artículo científico publicado en 2016

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.

artículo científico publicado en 2015

TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity

artículo científico publicado en 2008

Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channels

artículo científico publicado en 2007

Lista de obras de

A minimal isoform of the TMEM16A protein associated with chloride channel activity.

A quantitative description of the activation and inhibition of CFTR by potentiators: Genistein.

Alpha-aminoazaheterocyclic-methylglyoxal adducts do not inhibit cystic fibrosis transmembrane conductance regulator chloride channel activity.

Altered channel gating mechanism for CFTR inhibition by a high-affinity thiazolidinone blocker

Antihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations.

Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia.

Block of CFTR-dependent chloride currents by inhibitors of multidrug resistance-associated proteins.

CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds

CFTR pharmacology.

Ca2+-activated Cl- channels

Correction of G551D-CFTR transport defect in epithelial monolayers by genistein but not by CPX or MPB-07.

Direct interaction of a CFTR potentiator and a CFTR corrector with phospholipid bilayers

Double mechanism for apical tryptophan depletion in polarized human bronchial epithelium

Dual activity of aminoarylthiazoles on the trafficking and gating defects of the cystic fibrosis transmembrane conductance regulator chloride channel caused by cystic fibrosis mutations.

Effect of inflammatory stimuli on airway ion transport.

Epithelial sodium channel inhibition in primary human bronchial epithelia by transfected siRNA.

Epithelial sodium channel silencing as a strategy to correct the airway surface fluid deficit in cystic fibrosis

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel

Evidence for direct CFTR inhibition by CFTR(inh)-172 based on Arg347 mutagenesis.

Functional analysis of acid-activated Cl⁻ channels: properties and mechanisms of regulation.

Functional and pharmacological induced structural changes of the cystic fibrosis transmembrane conductance regulator in the membrane solved using SAXS.

Functional human CFTR produced by a stable minichromosome

Gelsolin Secretion in Interleukin-4–treated Bronchial Epithelia and in Asthmatic Airways

High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening

High-throughput screening of libraries of compounds to identify CFTR modulators.

IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro

In vitro recapitulation of the site-specific editing (to wild-type) of mutant IDS mRNA transcripts, and the characterization of IDS protein translated from the edited mRNAs

Lectin conjugates as potent, nonabsorbable CFTR inhibitors for reducing intestinal fluid secretion in cholera.

Modulation of cystic fibrosis transmembrane conductance regulator (CFTR) activity and genistein binding by cytosolic pH.

Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators.

Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides

On the measurement of the functional properties of the CFTR.

Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways.

Pharmacological rescue of mutant CFTR protein improves the viscoelastic properties of CF mucus.

Pharmacological therapy for cystic fibrosis: from bench to bedside

Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating

Proteomic analysis of the airway surface liquid: modulation by proinflammatory cytokines

Regulation of TMEM16A chloride channel properties by alternative splicing

Rheological Properties of Cystic Fibrosis Bronchial Secretion and in Vitro Drug Permeation Study: The Effect of Sodium Bicarbonate

Small molecule anionophores promote transmembrane anion permeation matching CFTR activity

Small-molecule correctors of defective DeltaF508-CFTR cellular processing identified by high-throughput screening.

Structure of wild type and mutant F508del CFTR: A small-angle X-ray scattering study of the protein-detergent complexes.

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.

TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity

Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channels