Lista de obras -

A Rabbit Model for Testing Helper-Dependent Adenovirus-Mediated Gene Therapy for Vein Graft Atherosclerosis

artículo científico publicado en 2017

A Rabbit Model of Durable Transgene Expression in Jugular Vein to Common Carotid Artery Interposition Grafts

A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre.

artículo científico publicado en 2006

ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation

scientific article published on 02 October 2018

Adenoviral Gene Transfer in Arteries of Hypercholesterolemic Nonhuman Primates ⬇️

artículo científico publicado el 10 de abril de 1998

Aortopathy in a Mouse Model of Marfan Syndrome Is Not Mediated by Altered Transforming Growth Factor β Signaling

artículo científico publicado en 2017

Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits

artículo científico publicado en 2017

Apolipoprotein A-I vascular gene therapy reduces vein-graft atherosclerosis

artículo científico publicado en 2023

Assessment of Subclinical Atherosclerosis in Asymptomatic People In Vivo: Measurements Suitable for Biomarker and Mendelian Randomization Studies

artículo científico publicado en 2024

Cationic Liposomes Enhance Adenovirus Entry via a Pathway Independent of the Fiber Receptor andαv-Integrins ⬇️

artículo científico publicado el 1 de marzo de 1998

Constriction of carotid arteries by urokinase-type plasminogen activator requires catalytic activity and is independent of NH(2)-terminal domains

scholarly article by Philip G Massey et al published November 2009 in Thrombosis and Haemostasis

Efficient gene transfer and durable transgene expression in grafted rabbit veins

artículo científico publicado en 2015

Endothelium-Specific In Vivo Gene Transfer ⬇️

artículo científico publicado el 1 de septiembre de 1995

Exosome-Mediated Transfer of Anti-miR-33a-5p from Transduced Endothelial Cells Enhances Macrophage and Vascular Smooth Muscle Cell Cholesterol Efflux

artículo científico publicado en 2020

Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis

artículo científico publicado en 2011

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction ⬇️

artículo científico publicado el 1 de julio de 1997

Gene therapy for arterial thrombosis ⬇️

artículo científico publicado el 1 de septiembre de 1997

Helper-dependent adenoviral vector achieves prolonged, stable expression of interleukin-10 in rabbit carotid arteries but does not limit early atherogenesis

artículo científico publicado en 2011

Helper-dependent adenoviral vectors are superior in vitro to first-generation vectors for endothelial cell-targeted gene therapy

artículo científico publicado en 2010

Helper-dependent adenovirus is superior to first-generation adenovirus for expressing transgenes in atherosclerosis-prone arteries

artículo científico publicado en 2011

Identification of intracellular pathways through which TGF-beta1 upregulates PAI-1 expression in endothelial cells

artículo científico publicado en 2005

Improved animal models for testing gene therapy for atherosclerosis.

artículo científico publicado en 2014

Improved vascular gene transfer with a helper-dependent adenoviral vector

artículo científico publicado en 2004

In Vivo Gene Transfer to the Rabbit Common Carotid Artery Endothelium.

artículo científico publicado en 2018

In vivo expression of a conditional TGF-beta1 transgene: no evidence for TGF-beta1 transgene expression in SM22alpha-tTA transgenic mice

artículo científico publicado en 2005

Inclusion of the E3 Region in an Adenoviral Vector Decreases Inflammation and Neointima Formation After Arterial Gene Transfer ⬇️

artículo científico publicado el 1 de noviembre de 2001

Increased expression of urokinase during atherosclerotic lesion development causes arterial constriction and lumen loss, and accelerates lesion growth

artículo científico publicado en 2002

Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta

scientific article published on 10 December 2020

Level of macrophage uPA expression is an important determinant of atherosclerotic lesion growth in Apoe-/- mice.

artículo científico publicado en 2009

Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice ⬇️

artículo científico publicado el 15 de octubre de 1998

Local Vascular Gene Therapy With Apolipoprotein A-I to Promote Regression of Atherosclerosis

artículo científico publicado en 2016

Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death

artículo científico publicado en 2004

Mechanisms of TGF-beta1-induced intimal growth: plasminogen-independent activities of plasminogen activator inhibitor-1 and heterogeneous origin of intimal cells

artículo científico publicado en 2007

Mechanisms of cardiac fibrosis induced by urokinase plasminogen activator

artículo científico publicado en 2006

Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins

artículo científico publicado en 2011

New Mouse Model of Abdominal Aortic Aneurysm: Put Out to Expand

artículo científico publicado en 2017

Novel expression cassettes for increasing apolipoprotein AI transgene expression in vascular endothelial cells

Overexpression of endothelial nitric oxide synthase improves endothelium-dependent vasodilation in arteries infused with helper-dependent adenovirus

artículo científico publicado en 2012

Overexpression of transforming growth factor β1 in arterial endothelium causes hyperplasia, apoptosis, and cartilaginous metaplasia ⬇️

artículo científico publicado el 9 de junio de 1998

Overexpression of urokinase by macrophages or deficiency of plasminogen activator inhibitor type 1 causes cardiac fibrosis in mice

artículo científico publicado en 2004

Overexpression of urokinase by plaque macrophages causes histological features of plaque rupture and increases vascular matrix metalloproteinase activity in aged apolipoprotein e-null mice

artículo científico publicado en 2010

Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture

artículo científico publicado en 2020

Plasminogen mediates the atherogenic effects of macrophage-expressed urokinase and accelerates atherosclerosis in apoE-knockout mice

artículo científico publicado en 2008

Plasminogen promotes cholesterol efflux by the ABCA1 pathway.

artículo científico publicado en 2017

Postnatal Deletion of the Type II Transforming Growth Factor-β Receptor in Smooth Muscle Cells Causes Severe Aortopathy in Mice

artículo científico publicado en 2015

Receptor-mediated regulation of plasminogen activator function: plasminogen activation by two directly membrane-anchored forms of urokinase

scientific article published on 01 September 2000

Reduction of mouse atherosclerosis by urokinase inhibition or with a limited-spectrum matrix metalloproteinase inhibitor

artículo científico publicado en 2015

Regional Variability in the Time Course of TGF-β1 Expression, Cellular Proliferation and Extracellular Matrix Expansion following Arterial Injury ⬇️

artículo científico publicado el 1 de enero de 1997

Regulated transgene expression in vascular smooth muscle

artículo científico publicado en 2005

Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries

scientific article published on 05 February 2009

Stable In Vivo Transgene Expression in Endothelial Cells with Helper-Dependent Adenovirus: Roles of Promoter and Interleukin-10.

artículo científico publicado en 2016

TGF-[beta]1 limits plaque growth, stabilizes plaque structure, and prevents aortic dilation in apolipoprotein E-null mice.

artículo científico publicado en 2009

TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms

artículo científico publicado en 2017

Targeted rearrangement of floxed alleles in smooth muscle cells in vivo

artículo científico publicado en 2007

Targeting and delivery of microRNA-targeting antisense oligonucleotides in cardiovascular diseases

artículo científico publicado en 2023

Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways

artículo científico publicado en 2005

Transforming growth factor-β signaling in myogenic cells regulates vascular morphogenesis, differentiation, and matrix synthesis

artículo científico publicado en 2011

What's the Skinny on Elastin Deficiency and Supravalvular Aortic Stenosis?

artículo científico publicado en 2017

Lista de obras de

A Rabbit Model for Testing Helper-Dependent Adenovirus-Mediated Gene Therapy for Vein Graft Atherosclerosis

A Rabbit Model of Durable Transgene Expression in Jugular Vein to Common Carotid Artery Interposition Grafts

A critical developmental role for tgfbr2 in myogenic cell lineages is revealed in mice expressing SM22-Cre, not SMMHC-Cre.

ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation

Adenoviral Gene Transfer in Arteries of Hypercholesterolemic Nonhuman Primates ⬇️

Aortopathy in a Mouse Model of Marfan Syndrome Is Not Mediated by Altered Transforming Growth Factor β Signaling

Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits

Apolipoprotein A-I vascular gene therapy reduces vein-graft atherosclerosis

Assessment of Subclinical Atherosclerosis in Asymptomatic People In Vivo: Measurements Suitable for Biomarker and Mendelian Randomization Studies

Cationic Liposomes Enhance Adenovirus Entry via a Pathway Independent of the Fiber Receptor andαv-Integrins ⬇️

Constriction of carotid arteries by urokinase-type plasminogen activator requires catalytic activity and is independent of NH(2)-terminal domains

Efficient gene transfer and durable transgene expression in grafted rabbit veins

Endothelium-Specific In Vivo Gene Transfer ⬇️

Exosome-Mediated Transfer of Anti-miR-33a-5p from Transduced Endothelial Cells Enhances Macrophage and Vascular Smooth Muscle Cell Cholesterol Efflux

Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction ⬇️

Gene therapy for arterial thrombosis ⬇️

Helper-dependent adenoviral vector achieves prolonged, stable expression of interleukin-10 in rabbit carotid arteries but does not limit early atherogenesis

Helper-dependent adenoviral vectors are superior in vitro to first-generation vectors for endothelial cell-targeted gene therapy

Helper-dependent adenovirus is superior to first-generation adenovirus for expressing transgenes in atherosclerosis-prone arteries

Identification of intracellular pathways through which TGF-beta1 upregulates PAI-1 expression in endothelial cells

Improved animal models for testing gene therapy for atherosclerosis.

Improved vascular gene transfer with a helper-dependent adenoviral vector

In Vivo Gene Transfer to the Rabbit Common Carotid Artery Endothelium.

In vivo expression of a conditional TGF-beta1 transgene: no evidence for TGF-beta1 transgene expression in SM22alpha-tTA transgenic mice

Inclusion of the E3 Region in an Adenoviral Vector Decreases Inflammation and Neointima Formation After Arterial Gene Transfer ⬇️

Increased expression of urokinase during atherosclerotic lesion development causes arterial constriction and lumen loss, and accelerates lesion growth

Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta

Level of macrophage uPA expression is an important determinant of atherosclerotic lesion growth in Apoe-/- mice.

Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice ⬇️

Local Vascular Gene Therapy With Apolipoprotein A-I to Promote Regression of Atherosclerosis

Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death

Mechanisms of TGF-beta1-induced intimal growth: plasminogen-independent activities of plasminogen activator inhibitor-1 and heterogeneous origin of intimal cells

Mechanisms of cardiac fibrosis induced by urokinase plasminogen activator

Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins

New Mouse Model of Abdominal Aortic Aneurysm: Put Out to Expand

Novel expression cassettes for increasing apolipoprotein AI transgene expression in vascular endothelial cells

Overexpression of endothelial nitric oxide synthase improves endothelium-dependent vasodilation in arteries infused with helper-dependent adenovirus

Overexpression of transforming growth factor β1 in arterial endothelium causes hyperplasia, apoptosis, and cartilaginous metaplasia ⬇️

Overexpression of urokinase by macrophages or deficiency of plasminogen activator inhibitor type 1 causes cardiac fibrosis in mice

Overexpression of urokinase by plaque macrophages causes histological features of plaque rupture and increases vascular matrix metalloproteinase activity in aged apolipoprotein e-null mice

Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture

Plasminogen mediates the atherogenic effects of macrophage-expressed urokinase and accelerates atherosclerosis in apoE-knockout mice

Plasminogen promotes cholesterol efflux by the ABCA1 pathway.

Postnatal Deletion of the Type II Transforming Growth Factor-β Receptor in Smooth Muscle Cells Causes Severe Aortopathy in Mice

Receptor-mediated regulation of plasminogen activator function: plasminogen activation by two directly membrane-anchored forms of urokinase

Reduction of mouse atherosclerosis by urokinase inhibition or with a limited-spectrum matrix metalloproteinase inhibitor

Regional Variability in the Time Course of TGF-β1 Expression, Cellular Proliferation and Extracellular Matrix Expansion following Arterial Injury ⬇️

Regulated transgene expression in vascular smooth muscle

Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries

Stable In Vivo Transgene Expression in Endothelial Cells with Helper-Dependent Adenovirus: Roles of Promoter and Interleukin-10.

TGF-[beta]1 limits plaque growth, stabilizes plaque structure, and prevents aortic dilation in apolipoprotein E-null mice.

TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms

Targeted rearrangement of floxed alleles in smooth muscle cells in vivo

Targeting and delivery of microRNA-targeting antisense oligonucleotides in cardiovascular diseases

Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways

Transforming growth factor-β signaling in myogenic cells regulates vascular morphogenesis, differentiation, and matrix synthesis

What's the Skinny on Elastin Deficiency and Supravalvular Aortic Stenosis?