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A Genomewide Pharmacogenetic Study of Growth Hormone Responsiveness

scientific article published on 11 July 2020

A pharmacokinetic and dosing study of intravenous insulin-like growth factor-I and IGF-binding protein-3 complex to preterm infants

artículo científico publicado en 2009

A rapid method for analyzing serum pro-insulin-like growth factor-II in patients with non-islet cell tumor hypoglycemia

artículo científico publicado en 2005

Abnormal growth in noonan syndrome: genetic and endocrine features and optimal treatment

artículo científico publicado en 2008

Acid-labile subunit deficiency and growth failure: description of two novel cases

artículo científico publicado en 2010

Acromegaly or chronic renal failure: a diagnostic dilemma

artículo científico publicado en 1997

Adult height prediction by bone age determination in children with isolated growth hormone deficiency

scientific article published on 01 April 2020

An Intronic Growth Hormone Receptor Mutation Causing Activation of a Pseudoexon Is Associated with a Broad Spectrum of Growth Hormone Insensitivity Phenotypes

scientific article published on 05 December 2006

Analysis of the intracellular signalling domain of the human growth hormone receptor in children with idiopathic short stature

scientific article published on 01 April 2000

Anti-inflammatory and growth-stimulating effects precede nutritional restitution during enteral feeding in Crohn disease

artículo científico publicado en 2004

Assessment of growth hormone status in acromegaly: what biochemical markers to measure and how?

artículo científico publicado en 2000

Baseline Characteristics and Gender Differences in Prepubertal Children Treated with Growth Hormone in Europe, USA, and Japan: 25 Years' KIGS® Experience (1987-2012) and Review

artículo científico publicado en 2016

Change in baseline characteristics over 20 years of adults with growth hormone (GH) deficiency on GH replacement therapy

scientific article published on 01 December 2019

Changes in protein turnover, IGF-I and IGF binding proteins in children with cancer ⬇️

artículo científico publicado el 1 de enero de 1998

Changes in serum IGF-I and IGFBP-3 concentrations during the IGF-I generation test performed prospectively in children with short stature

artículo científico publicado en 1998

Childhood obesity

artículo científico publicado en 2005

Combined treatment with GH and IGF-I: additive effect on cortical bone mass but not on linear bone growth in female rats

artículo científico publicado en 2014

Comparison of continuation or cessation of growth hormone (GH) therapy on body composition and metabolic status in adolescents with severe GH deficiency at completion of linear growth.

artículo científico publicado en 2004

Correlation between cortisol and insulin-like growth factor-binding proteins (IGFBPs) under physiological conditions in children

artículo científico publicado en 1999

Dehydroepiandrosterone (DHEA) replacement reduces growth hormone (GH) dose requirement in female hypopituitary patients on GH replacement

artículo científico publicado en 2006

Dehydroepiandrosterone improves psychological well-being in male and female hypopituitary patients on maintenance growth hormone replacement

artículo científico publicado en 2006

Deterioration of visual acuity associated with growth hormone therapy in a child with extreme short stature and high hypermetropia

artículo científico publicado en 2006

Diabetes in patients with acromegaly treated with pegvisomant: observations from acrostudy.

artículo científico publicado en 2018

Diagnostic and therapeutic advances in growth hormone insensitivity

artículo científico publicado en 2005

Different states of clinical control are associated with changes in IGF-I and IGFBPs in children with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

artículo científico publicado en 2004

Dose-related effects of growth hormone on IGF-I and IGF-binding protein-3 levels in non-islet cell tumour hypoglycaemia

artículo científico publicado en 1998

Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion

artículo científico publicado en 2000

Effects of recombinant human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion

artículo científico publicado en 1999

Efficacy of Growth Hormone Treatment in Children with Type 1 Diabetes Mellitus and Growth Hormone Deficiency-An Analysis of KIGS Data.

artículo científico publicado en 2018

Endocrine assessment, molecular characterization and treatment of growth hormone insensitivity disorders

artículo científico publicado en 2006

Endocrine regulation of longitudinal bone growth

artículo científico

Evidence for a continuum of genetic, phenotypic, and biochemical abnormalities in children with growth hormone insensitivity.

artículo científico publicado en 2011

Excellent growth response to growth hormone therapy in a child with PTPN11-negative Noonan syndrome and features of growth hormone resistance

artículo científico publicado en 2007

Final height in patients with idiopathic short stature and high growth hormone responses to stimulation tests

artículo científico publicado en 2006

Girls with virilisation in childhood: a diagnostic protocol for investigation ⬇️

artículo científico publicado el 1 de mayo de 1997

Growth Hormone Treatment in Children With Prader-Willi Syndrome: Three Years of Longitudinal Data in Prepubertal Children and Adult Height Data From the KIGS Database

artículo científico publicado en 2017

Growth failure and intestinal inflammation

artículo científico publicado en 2001

Growth hormone (GH) insensitivity syndrome due to a GH receptor truncated after Box1, resulting in isolated failure of STAT 5 signal transduction

artículo científico publicado en 2004

Growth hormone insensitivity and severe short stature in siblings: a novel mutation at the exon 13-intron 13 junction of the STAT5b gene

artículo científico publicado en 2007

Growth hormone insensitivity: pathophysiology, diagnosis, clinical variation and future perspectives.

artículo científico publicado en 2001

Growth hormone receptor gene mutations in two Italian patients with Laron Syndrome

scientific article published on 01 May 2007

Growth hormone replacement does not increase serum prostate-specific antigen in hypopituitary men over 50 years

artículo científico publicado en 2002

Growth hormone therapy for non-islet cell tumor hypoglycemia

scientific article published on 01 August 2002

Growth in Crohn's disease

artículo científico publicado en 1999

Highlights from the Second European Workshop on Growth Plate Research 2010

scientific article published on 01 December 2010

How should insulin-like growth factor I be measured? A consensus statement.

artículo científico publicado en 2001

Human acid-labile subunit deficiency: clinical, endocrine and metabolic consequences.

scientific article published on September 2009

Hypoglycaemia secondary to the secretion of pro-insulin like growth factor II by a metastatic neuroendocrine tumour with sarcomatous differentiation

artículo científico publicado en 2003

IGF-I levels rise and GH responses to GHRH decrease during long-term prednisone treatment in man

scientific article published on 01 January 1999

IGFs and IGFBPs in GH insensitivity.

artículo científico publicado en 2005

Identification of the types of insulin-like growth factor-binding proteins that are secreted by muscle cells in vitro

scientific article published on 01 May 1989

Idiopathic short stature: will genetics influence the choice between GH and IGF-I therapy?

artículo científico publicado en 2007

Improvements in Body Composition after 4 Years of Growth Hormone Treatment in Adult-Onset Hypopituitarism Compared to Age-Matched Controls

artículo científico publicado en 2019

Increased levels of insulin-like growth factor binding protein-2 in sera and tumours from patients with colonic neoplasia with and without acromegaly

artículo científico publicado en 2001

Individualised growth response optimisation (iGRO) tool: an accessible and easy-to-use growth prediction system to enable treatment optimisation for children treated with growth hormone

artículo científico publicado en 2017

Insulin-like growth factor (IGF)-I gene deletion

artículo científico publicado en 2002

Insulin-like growth factor -I deficiency

artículo científico publicado en 2001

Insulin-like growth factor axis of gluten-sensitive dogs during a gluten challenge

scientific article published on 01 July 1998

Insulin-like growth factor-I and- II in combination inhibit the release of growth hormone-releasing hormone from the rat hypothalamus in vitro

artículo científico publicado en 1996

Insulin-like growth factor-I deficiency caused by a partial deletion of the IGF-I gene: effects of rhIGF-I therapy

artículo científico publicado en 1999

Insulin-like growth factor-binding proteins and neoplasia: an overview

artículo científico publicado en 2000

Insulin‐like growth factor I gene deletion causing intrauterine growth retardation and severe short stature ⬇️

artículo científico publicado el 1 de noviembre de 1997

Interleukin-1beta (IL-1beta) and IL-6 modulate insulin-like growth factor-binding protein (IGFBP) secretion in colon cancer epithelial (Caco-2) cells.

artículo científico publicado en 2003

Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene

artículo científico publicado en 1996

Is there a medical need to explore the clinical use of insulin-like growth factor I?

artículo científico publicado en 2001

Isolated growth hormone deficiency

artículo científico publicado en 2007

Long-term treatment with pegvisomant: observations from 2090 acromegaly patients in ACROSTUDY

artículo científico publicado en 2018

Low circulating IGF-I levels in hyperthyroidism are associated with decreased GH response to GH-releasing hormone

scientific article published on 01 November 1995

Near Adult Height in Girls with Turner Syndrome Treated with Growth Hormone Following Either Induced or Spontaneous Puberty

scientific article published on 18 June 2019

Near-Adult Height After Growth Hormone Treatment in Children Born Prematurely-Data From KIGS

artículo científico publicado en 2020

New neoplasm during GH replacement in adults with pituitary deficiency following malignancy- a KIMS analysis

artículo científico publicado en 2017

Normal Physiology of Growth Hormone and Insulin-Like Growth Factors in Childhood

artículo científico publicado en 2015

Normal growth hormone secretion in growth hormone insufficient children retested after completion of linear growth

scientific article published on 01 November 1996

Novel growth hormone receptor mutation in a Chinese patient with Laron syndrome

artículo científico publicado en 2005

Nutritional modulation of canine insulin-like growth factors and their binding proteins

artículo científico publicado en 1998

Obesity due to melanocortin 4 receptor (MC4R) deficiency is associated with increased linear growth and final height, fasting hyperinsulinemia, and incompletely suppressed growth hormone secretion

artículo científico publicado en 2010

Optimizing growth hormone replacement therapy by dose titration in hypopituitary adults.

artículo científico publicado en 1998

Pharmacokinetic studies of recombinant human insulin-like growth factor I (rhIGF-I)/rhIGF-binding protein-3 complex administered to patients with growth hormone insensitivity syndrome

artículo científico publicado en 2006

Phenotypic aspects of growth hormone- and IGF-I-resistant syndromes.

artículo científico publicado en 2009

Phenotypic variability in growth hormone insensitivity

artículo científico publicado en 2002

Pituitary function and the response to GH therapy in patients with Langerhans cell histiocytosis: analysis of the KIMS database

artículo científico publicado en 2022

Postnatally elevated levels of insulin-like growth factor (IGF)-II fail to rescue the dwarfism of IGF-I-deficient mice except kidney weight

artículo científico publicado en 2006

Pregnancy in acromegaly patients treated with pegvisomant

artículo científico publicado en 2014

Pseudo-precocious puberty caused by a juvenile granulosa cell tumour secreting androstenedione, inhibin and insulin-like growth factor-I.

artículo científico publicado en 2004

Racial/Ethnic Disparities in US Pediatric Growth Hormone Treatment

scientific article published on 21 August 2018

Radiotherapy, Especially at Young Age, Increases the Risk for De Novo Brain Tumors in Patients Treated for Pituitary/Sellar Lesions

artículo científico publicado en 2017

Reduced serum insulin-like growth factor (IGF) and IGF-binding protein-3 concentrations in two deerhounds with congenital portosystemic shunts

artículo científico publicado en 2000

Relationships between Serum IGF-1, IGFBP-2, Interleukin-1Beta and Interleukin-6 in Inflammatory Bowel Disease

artículo científico publicado en 2004

Relative risks of contributing factors to morbidity and mortality in adults with craniopharyngioma on GH replacement

artículo científico publicado en 2017

Response to Growth Hormone Treatment after Radiation Therapy Depends on Location of Irradiation

scientific article published on 24 July 2020

Response to Letter to the Editor: "A Genome-Wide Pharmacogenetic Study of Growth Hormone Responsiveness"

artículo científico publicado en 2020

Responsiveness of IGF-I and IGFBP-3 to therapeutic intervention in children and adolescents with Crohn's disease.

artículo científico publicado en 1998

SAT-444 Pituitary Function and the Response to GH Replacement Therapy in Patients with Histiocytosis: Analysis of the Pfizer International Metabolic Database (KIMS)

SUN-LB079 Acrostudy - Safety And Treatment Outcomes In 2221 Patients With Acromegaly Treated With Pegvisomant: Real World Experience.

artículo científico publicado en 2019

SUN-LB080 ACROSTUDY - Safety and Efficacy of a Cohort of 110 Naïve Patients with Acromegaly Treated with Pegvisomant

artículo científico publicado en 2019

Secular Trends on Birth Parameters, Growth, and Pubertal Timing in Girls with Turner Syndrome.

artículo científico publicado en 2018

Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 in girls with premature thelarche

artículo científico publicado en 2003

Serum insulin-like growth factor (IGF)-I concentrations are reduced by short-term dietary restriction and restored by refeeding in domestic cats (Felis catus)

scientific article published on 01 October 1999

Signal transduction in child health: closing the gap between clinical and basic research

artículo científico publicado en 2010

Standard and low-dose IGF-I generation tests and spontaneous growth hormone secretion in children with idiopathic short stature

scientific article published on 01 February 2004

Targeted literature review of the humanistic and economic burden of adult growth hormone deficiency

article

The 'dawn phenomenon' in adolescents with insulin dependent diabetes mellitus: possible contribution of insulin-like growth factor binding protein-1

scientific article published on 01 November 1995

The differential regulation of the circulating levels of the insulin-like growth factors and their binding proteins (IGFBP) 1, 2 and 3 after elective abdominal surgery

artículo científico publicado en 1996

The effect of cessation of growth hormone (GH) therapy on bone mineral accretion in GH-deficient adolescents at the completion of linear growth.

artículo científico publicado en 2003

The effect of recombinant human insulin-like growth factor-I treatment on growth hormone secretion in two subjects with growth hormone insensitivity (Laron syndrome)

artículo científico publicado en 1993

The insulin-like growth factor I generation test in the investigation of short stature

scientific article published on 01 April 1994

The prevalence of the metabolic syndrome and associated cardiovascular complications in adult-onset GHD during GH replacement: a KIMS analysis.

artículo científico publicado en 2018

The short-term effects of growth hormone therapy on height velocity and cardiac ventricular wall thickness in children with Noonan's syndrome

artículo científico publicado en 1996

Therapeutic applications of the insulin-like growth factors

artículo científico publicado en 2004

Treatment with Growth Hormone in Noonan Syndrome Observed during 25 Years of KIGS: Near Adult Height and Outcome Prediction

artículo científico publicado en 2019

Weight gain in Turner Syndrome: association to puberty induction? - longitudinal analysis of KIGS data

artículo científico publicado en 2016

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