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A Novel Micro-assay for Insulin Autoantibodies ⬇️

artículo científico publicado el 1 de octubre de 1997

A comparison of the baseline metabolic profiles between Diabetes Prevention Trial-Type 1 and TrialNet Natural History Study participants

artículo científico publicado en 2011

A longitudinal study of GAD65 and ICA512 autoantibodies during the progression to type 1 diabetes in Diabetes Prevention Trial-Type 1 (DPT-1) participants

artículo científico publicado en 2011

A new approach for diagnosing type 1 diabetes in autoantibody-positive individuals based on prediction and natural history

artículo científico publicado en 2014

A novel high-throughput method for accurate, rapid, and economical measurement of multiple type 1 diabetes autoantibodies

scientific article published on 01 October 2000

A risk score for type 1 diabetes derived from autoantibody-positive participants in the diabetes prevention trial-type 1.

artículo científico publicado en 2007

Acceleration of the Loss of the First-Phase Insulin Response During the Progression to Type 1 Diabetes in Diabetes Prevention Trial–Type 1 Participants ⬇️

artículo científico publicado el 17 de julio de 2013

Analysis of T-Cell Assays to Measure Autoimmune Responses in Subjects With Type 1 Diabetes

article

Analysis of antibody markers, DRB1, DRB5, DQA1 and DQB1 genes and modeling of DR2 molecules in DR2-positive patients with insulin-dependent diabetes mellitus

artículo científico

Anti-PD-1 and Anti-PDL-1 Monoclonal Antibodies Causing Type 1 Diabetes

artículo científico publicado en 2015

Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial ⬇️

artículo científico publicado el 27 de junio de 2011

Assessment of Beta Cell Mass and Function by AIRmax and IVGTT in High Risk Subjects for Type 1 Diabetes

artículo científico publicado en 2017

Association between autoantibody markers and subtypes of DR4 and DR4-DQ in Swedish children with insulin-dependent diabetes reveals closer association of tyrosine pyrophosphatase autoimmunity with DR4 than DQ8

artículo científico publicado en 1998

Associations of HbA1c with the timing of C-peptide responses during the oral glucose tolerance test at the diagnosis of type 1 diabetes

scientific article published on 15 April 2019

Autoantibodies to pancreatic islet cells and insulin in IDDM families: the GAW5 data

artículo científico publicado en 1989

Autoimmunity and clinical course in children with type 1, type 2, and type 1.5 diabetes

artículo científico publicado en 2005

Autoimmunity to insulin, beta cell dysfunction, and development of insulin-dependent diabetes mellitus

artículo científico publicado en 1986

Autoimmunity to islet proteins in children diagnosed with new-onset diabetes

artículo científico publicado en 2004

Beta cell function in the preclinical period of insulin-dependent diabetes

artículo científico publicado en 1987

Beta-cell dysfunction in nondiabetic HLA identical siblings of insulin-dependent diabetics

artículo científico publicado en 1982

Beta-cell function and insulin sensitivity in nondiabetic HLA-identical siblings of insulin-dependent diabetics

artículo científico publicado en 1987

Biomarkers and immune-modulating therapies for Type 2 diabetes ⬇️

artículo científico publicado el 14 de agosto de 2012

C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001.

artículo científico publicado en 2004

Cellular immune responses to human islet proteins in antibody-positive type 2 diabetic patients.

artículo científico publicado en 1999

Challenges in developing endpoints for type 1 diabetes intervention studies

artículo científico publicado en 2009

Changes in GAD65Ab-specific antiidiotypic antibody levels correlate with changes in C-peptide levels and progression to islet cell autoimmunity

artículo científico publicado en 2010

Comparison of two insulin assays for first-phase insulin release in type 1 diabetes prediction and prevention studies.

artículo científico publicado en 2011

Correlations of in vivo beta-cell function tests with beta-cell mass and pancreatic insulin content in streptozocin-administered baboons

artículo científico publicado en 1991

Daniel Porte Jr.: A Leader in Our Understanding of the Role of Defective Insulin Secretion and Action in Obesity and Type 2 Diabetes

artículo científico publicado en 2020

Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment

artículo científico publicado en 2015

Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis.

artículo científico publicado en 2016

Early and late C-peptide responses during oral glucose tolerance testing are oppositely predictive of type 1 diabetes in autoantibody-positive individuals

scientific article published on 31 January 2020

Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

artículo científico publicado en 2018

Effect of insulin resistance and hyperglycemia on proinsulin release in a primate model of diabetes mellitus

artículo científico publicado en 1992

Effect of nicotinic acid-induced insulin resistance on pancreatic B cell function in normal and streptozocin-treated baboons ⬇️

artículo científico publicado el 1 de abril de 1991

Effects of an anti-CD5 immunoconjugate (CD5-plus) in recent onset type I diabetes mellitus: a preliminary investigation. The CD5 Diabetes Project Team

artículo científico publicado en 1993

Effects of exenatide alone and in combination with daclizumab on beta-cell function in long-standing type 1 diabetes

scientific article published on 06 October 2009

Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1.

artículo científico publicado en 2005

Epitope analysis of insulin autoantibodies using recombinant Fab.

artículo científico publicado en 2005

Equivalent insulin resistance in latent autoimmune diabetes in adults (LADA) and type 2 diabetic patients

artículo científico publicado en 2007

Erratum. Validation of the Diabetes Prevention Trial-Type 1 Risk Score in the TrialNet Natural History Study. Diabetes Care 2011;34:1785-1787.

artículo científico publicado en 2018

Evaluation of a novel radioimmunoassay using125I-labelled human recombinant GAD65 for the determination of glutamic acid decarboxylase (GAD65) autoantibodies

artículo científico publicado en 2000

Expression of GAD65 and islet cell antibody (ICA512) autoantibodies among cytoplasmic ICA+ relatives is associated with eligibility for the Diabetes Prevention Trial-Type 1.

artículo científico publicado en 2001

Fall in C-peptide during first 2 years from diagnosis: evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data

artículo científico publicado en 2012

Fifth International Serum Exchange Workshop for Insulin Autoantibody (IAA) Standardization. The Immunology and Diabetes Workshops and participating laboratories

artículo científico publicado el 1 de agosto de 1992

First test effect in intravenous glucose tolerance testing ⬇️

artículo científico publicado el 15 de agosto de 2013

Follow-up report on the diagnosis of diabetes mellitus

artículo científico publicado en 2003

Functional state of the beta cell affects expression of both forms of glutamic acid decarboxylase

artículo científico publicado en 1994

Future intervention trials in type 1 diabetes

artículo científico publicado en 2004

GAD vaccine reduces insulin loss in recently diagnosed type 1 diabetes: findings from a Bayesian meta-analysis

artículo científico publicado en 2016

GAD65 Antibody Epitope Patterns of Type 1.5 Diabetic Patients Are Consistent With Slow-Onset Autoimmune Diabetes

scientific article published on 01 August 2002

GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus

artículo científico publicado en 2012

Genetic and immunological findings in patients with newly diagnosed insulin-dependent diabetes mellitus. The Swedish Childhood Diabetes Study Group and The Diabetes Incidence in Sweden Study (DISS) Group

artículo científico publicado en 1996

Genetic and immunological markers of insulin dependent diabetes in Black Americans

artículo científico publicado en 1995

Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

article

Glucose and C-peptide changes in the perionset period of type 1 diabetes in the Diabetes Prevention Trial-Type 1.

artículo científico publicado en 2008

Glucose excursions between states of glycemia with progression to type 1 diabetes in the diabetes prevention trial-type 1 (DPT-1).

artículo científico publicado en 2010

HLA-DR4-Associated Disease: Oligonucleotide Probes Identify Specific Class II Susceptibility Genes in Type I Diabetes and Rheumatoid Arthritis

article

HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression

artículo científico publicado en 2016

HLA-related heterogeneity in seasonal patterns of diagnosis in Type 1 (insulin-dependent) diabetes

artículo científico publicado en 1984

Heterogeneity of islet pathology in two infants with recent onset diabetes mellitus

artículo científico publicado en 1995

Hydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial

artículo científico publicado en 2014

Identification of autoantibody-negative autoimmune type 2 diabetic patients ⬇️

artículo científico publicado en 2010

Immunogenetic analysis suggests different pathogenesis for obese and lean African-Americans with diabetic ketoacidosis

article

Immunology in the Clinic Review Series; focus on metabolic diseases: development of islet autoimmune disease in type 2 diabetes patients: potential sequelae of chronic inflammation ⬇️

artículo científico publicado el 1 de enero de 2012

Impact of C-peptide preservation on metabolic and clinical outcomes in the Diabetes Control and Complications Trial

artículo científico publicado en 2013

Impact of islet autoimmunity on the progressive β-cell functional decline in type 2 diabetes.

artículo científico publicado en 2014

Improved T cell assay for identification of type 1 diabetes patients

artículo científico publicado en 2009

Improved specificity of ICA assays in the Fourth International Immunology of Diabetes Serum Exchange Workshop

artículo científico publicado el 1 de diciembre de 1992

Incident dysglycemia and progression to type 1 diabetes among participants in the Diabetes Prevention Trial-Type 1

artículo científico publicado en 2009

Increased specificity and sensitivity of insulin antibody measurements in autoimmune thyroid disease and type I diabetes

artículo científico publicado en 1992

Increasing the accuracy of oral glucose tolerance testing and extending its application to individuals with normal glucose tolerance for the prediction of type 1 diabetes: the Diabetes Prevention Trial-Type 1.

artículo científico publicado en 2007

Insulin (auto)antibodies from human IDDM cross-react with retroviral antigen p73

artículo científico publicado en 1993

Insulin Antibodies and Insulin Autoantibodies ⬇️

artículo científico publicado el 1 de febrero de 1991

Insulin autoantibodies and insulin antibodies have similar binding characteristics

artículo científico publicado en 1999

Insulin autoantibodies measured by radioimmunoassay methodology are more related to insulin-dependent diabetes mellitus than those measured by enzyme-linked immunosorbent assay: results of the Fourth International Workshop on the Standardization of

artículo científico publicado en 1992

Intermolecular antigen spreading occurs during the preclinical period of human type 1 diabetes

artículo científico publicado en 2001

International comparison of C-peptide measurements

artículo científico publicado en 2007

Is Diabetes Mellitus a Continuous Spectrum? ⬇️

artículo científico publicado el 10 de noviembre de 2010

Is it time to take a different approach to screening people at high risk for type 1 diabetes?

artículo científico publicado en 2009

Is latent autoimmune diabetes in adults distinct from type 1 diabetes or just type 1 diabetes at an older age?

artículo científico publicado en 2005

Islet autoimmunity in phenotypic type 2 diabetes patients

artículo científico

Islet cell antibodies and glutamic acid decarboxylase antibodies, but not the clinical phenotype, help to identify type 1(1/2) diabetes in patients presenting with type 2 diabetes

artículo científico publicado en 2001

Islet-specific T-cell responses and proinflammatory monocytes define subtypes of autoantibody-negative ketosis-prone diabetes

scientific article published on 15 October 2013

Large-scale prospective T cell function assays in shipped, unfrozen blood samples: experiences from the multicenter TRIGR trial

artículo científico publicado en 2013

Latent autoimmune diabetes in adults (LADA) should be less latent

artículo científico publicado en 2005

MHC Class I Chain-Related Gene-A Is Associated with IA2 and IAA but Not GAD in Swedish Type 1 Diabetes Mellitus

article

Major histocompatibility complex class I molecule expression is normal on peripheral blood lymphocytes from patients with insulin-dependent diabetes mellitus

artículo científico publicado en 1996

Metabolic state of the pancreas affects end-point titre in the islet cell antibody assay

artículo científico publicado en 1991

Multiple factors affect the loss of measurable C-peptide over 6 years in newly diagnosed 15- to 35-year-old diabetic subjects

artículo científico publicado en 2007

Nicotinamide's effects on glucose metabolism in subjects at risk for IDDM

artículo científico publicado en 1996

Nitric oxide mediates IL-1beta stimulation of heat shock protein but not IL-1beta inhibition of glutamic acid decarboxylase

artículo científico publicado en 1999

Non-HLA type 1 diabetes genes modulate disease risk together with HLA-DQ and islet autoantibodies

artículo científico publicado en 2015

Non-human pancreas as substrate for cytoplasmic islet cell antibodies

artículo científico publicado en 1991

Nonprogression of subclinical beta-cell dysfunction among first-degree relatives of IDDM patients. 5-yr follow-up of the Seattle Family Study

artículo científico publicado en 1990

Nonprogression of subclinical beta-cell dysfunction among first-degree relatives of IDDM patients. 5-yr follow-up of the Seattle Family Study

Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1.

artículo científico publicado en 2009

Parenteral insulin suppresses T cell proliferation to islet antigens

artículo científico publicado en 2011

Patterns of metabolic progression to type 1 diabetes in the Diabetes Prevention Trial-Type 1.

artículo científico publicado en 2006

Peripheral blood mononuclear cell responses from type 1 diabetic patients and subjects at-risk for type 1 diabetes to human fetal pancreatic tissue proteins

scientific article published on 01 May 2000

Peripheral blood mononuclear cells of insulin-dependent diabetic patients respond to multiple islet cell proteins

artículo científico publicado en 1996

Precursor frequencies of T-cells reactive to insulin in recent onset type 1 diabetes mellitus

scientific article published on 01 August 2004

Prediction and Prevention of IDDM—1991 ⬇️

artículo científico publicado el 1 de agosto de 1991

Predictive value of islet cell and insulin autoantibodies for Type 1 (insulin-dependent) diabetes mellitus in a population-based study of newly-diagnosed diabetic and matched control children

scientific article published on 01 November 1992

Prevention versus intervention of type 1 diabetes ⬇️

artículo científico publicado el 10 de junio de 2013

Prognostic factors for the course of beta cell function in autoimmune diabetes

artículo científico publicado en 2000

Prospective evaluation of β-cell function in insulin antoantibody-positive relatives of insulin-dependent diabetic patients

artículo científico publicado en 1993

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function

artículo científico publicado en 1993

Reactivation of type 1 diabetes in patients receiving human fetal pancreatic tissue transplants without immunosuppression

scientific article published on 01 January 2000

Reactivation of type 1 diabetes in patients receiving human fetal pancreatic tissue transplants without immunosuppression

scientific article published on 01 May 2000

Recombinant Fabs of human monoclonal antibodies specific to the middle epitope of GAD65 inhibit type 1 diabetes-specific GAD65Abs

artículo científico publicado en 2003

Recommendations for the definition of clinical responder in insulin preservation studies

artículo científico publicado en 2014

Reduced insulin sensitivity in nondiabetic, HLA-identical siblings of insulin-dependent diabetic subjects.

artículo científico publicado en 1985

Relationship of Family History of Type 2 Diabetes, Hypoglycemia, and Autoantibodies to Weight Gain and Lipids With Intensive and Conventional Therapy in the Diabetes Control and Complications Trial ⬇️

artículo científico publicado el 1 de octubre de 2003

Relationship of beta-cell function and autoantibodies to progression and nonprogression of subclinical type 1 diabetes: follow-up of the Seattle Family Study

scientific article published on 01 January 1999

Responses of the pancreatic A cell during hypoglycemia and hyperglycemia are dependent on the B cell

artículo científico publicado en 1989

Risk for developing type 1 (insulin-dependent) diabetes mellitus and the presence of islet 64K antibodies

artículo científico publicado en 1991

Role of insulin resistance in predicting progression to type 1 diabetes

scientific article published on 29 May 2007

Sample size requirements for studies of treatment effects on beta-cell function in newly diagnosed type 1 diabetes

artículo científico publicado en 2011

Screening strategies for the identification of multiple antibody-positive relatives of individuals with type 1 diabetes

artículo científico publicado en 2003

Setting the Stage for Islet Autoimmunity in Type 2 Diabetes: Obesity-Associated Chronic Systemic Inflammation and Endoplasmic Reticulum (ER) Stress

scientific article published on 01 December 2019

Slowed Metabolic Decline after One Year of Oral Insulin Treatment among Individuals at High Risk for Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 and TrialNet Oral Insulin Prevention Trials

scientific article published on 21 May 2020

Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes

scientific article published on 07 February 2006

Standardization of C-peptide measurements

artículo científico publicado en 2008

Successful prospective prediction of type 1 diabetes in schoolchildren through multiple defined autoantibodies: an 8-year follow-up of the Washington State Diabetes Prediction Study

artículo científico publicado en 2002

Systematic variation and differences in insulin-autoantibody measurements

artículo científico publicado en 1989

T-cell responses to islet antigens improves detection of autoimmune diabetes and identifies patients with more severe beta-cell lesions in phenotypic type 2 diabetes

artículo científico publicado en 2007

The Appropriate Use of B-cell Function Testing in the Preclinical Period of Type 1 Diabetes ⬇️

artículo científico publicado el 1 de noviembre de 1991

The Effect of DPT-1 Intravenous Insulin Infusion and Daily Subcutaneous Insulin on Endogenous Insulin Secretion and Postprandial Glucose Tolerance

artículo científico publicado en 2015

The Fourth International Workshop on the Standardisation of Insulin Autoantibody Workshop

artículo científico publicado en 1990

The Pathological Evolution of Glucose Response Curves During the Progression to Type 1 Diabetes in the TrialNet Pathway to Prevention Study

artículo científico publicado en 2020

The Prediction of Type 1 Diabetes by Multiple Autoantibody Levels and Their Incorporation Into an Autoantibody Risk Score in Relatives of Type 1 Diabetic Patients ⬇️

artículo científico publicado el 1 de julio de 2013

The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results

artículo científico publicado en 2008

The Use of Electrochemiluminescence Assays to Predict Autoantibody and Glycemic Progression Toward Type 1 Diabetes in Individuals with Single Autoantibodies

artículo científico publicado en 2017

The application of the diabetes prevention trial-type 1 risk score for identifying a preclinical state of type 1 diabetes

artículo científico publicado en 2012

The association between the PTPN22 1858C>T variant and type 1 diabetes depends on HLA risk and GAD65 autoantibodies

artículo científico publicado en 2010

The contribution of insulin-dependent and insulin-independent glucose uptake to intravenous glucose tolerance in healthy human subjects

artículo científico publicado en 1994

The development and utility of a novel scale that quantifies the glycemic progression toward type 1 diabetes over 6 months

artículo científico publicado en 2015

The development, validation, and utility of the Diabetes Prevention Trial-Type 1 Risk Score (DPTRS).

artículo científico publicado en 2015

The effect of cytokines on expression of glutamic acid decarboxylase-65 in cultured islets

artículo científico publicado en 1995

The functional state of the beta cell modulates IL-1 and TNF-induced cytotoxicity

scientific article published on 01 August 1993

The influence of body mass index and age on C-peptide at the diagnosis of type 1 diabetes in children who participated in the diabetes prevention trial-type 1.

artículo científico publicado en 2017

The metabolic progression to type 1 diabetes as indicated by serial oral glucose tolerance testing in the Diabetes Prevention Trial-type 1.

artículo científico publicado en 2012

The shape of the glucose concentration curve during an oral glucose tolerance test predicts risk for type 1 diabetes

artículo científico publicado en 2017

Transcomplementation of HLA genes in IDDM. HLA-DQ alpha- and beta-chains produce hybrid molecules in DR3/4 heterozygotes

article

Transcomplementation of HLA genes in IDDM. HLA-DQ alpha- and beta-chains produce hybrid molecules in DR3/4 heterozygotes

artículo científico publicado en 1987

Trends of earlier and later responses of C-peptide to oral glucose challenges with progression to type 1 diabetes in diabetes prevention trial-type 1 participants

artículo científico publicado en 2009

Type 1 1/2 diabetes: myth or reality?

artículo científico publicado en 1999

Tyramine-mediated activation of sympathetic nerves inhibits insulin secretion in humans

artículo científico publicado en 2007

Use of the Diabetes Prevention Trial-Type 1 Risk Score (DPTRS) for improving the accuracy of the risk classification of type 1 diabetes

artículo científico publicado en 2014

Validation of the Diabetes Prevention Trial-Type 1 Risk Score in the TrialNet Natural History Study

artículo científico publicado en 2011

Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes.

artículo científico publicado en 2009

Visceral obesity, hepatic lipase activity, and dyslipidemia in type 1 diabetes

artículo científico publicado en 2003

What's in a name: latent autoimmune diabetes of adults, type 1.5, adult-onset, and type 1 diabetes

artículo científico publicado en 2003

β Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis

β cell death and dysfunction during type 1 diabetes development in at-risk individuals

artículo científico publicado en 2015

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