Lista de obras - Søren-Peter Olesen - Dominio Público Uruguay

A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation

artículo científico publicado en 2013

A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

artículo científico publicado en 2013

A radiolabeled peptide ligand of the hERG channel, [125I]-BeKm-1.

artículo científico publicado en 2003

A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome.

artículo científico publicado en 2008

AMP-activated protein kinase downregulates Kv7.1 cell surface expression

artículo científico publicado en 2012

ATP-dependent closure and reactivation of inward rectifier K+ channels in endothelial cells

scientific article published on 01 September 1993

Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

artículo científico publicado en 2008

Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).

artículo científico publicado en 2005

Activation of the human intermediate-conductance Ca(2+)-activated K(+) channel by 1-ethyl-2-benzimidazolinone is strongly Ca(2+)-dependent.

artículo científico publicado en 1999

An electrophysiological study of microvascular permeability and its modulation by chemical mediators

scientific article published on 01 January 1989

Analysis of the Antitumor Activity of Clotrimazole on A375 Human Melanoma Cells

artículo científico publicado en 2015

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

artículo científico publicado en 2014

BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle

artículo científico publicado en 2010

BK channel activators and their therapeutic perspectives

artículo científico publicado en 2014

BK channel modulators: a comprehensive overview

artículo científico publicado en 2008

Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif

artículo científico publicado en 2004

Biophysical characterization of the short QT mutation hERG-N588K reveals a mixed gain-and loss-of-function

artículo científico publicado en 2008

Blockade of Ca2+-activated K+ channels in T cells: an option for the treatment of multiple sclerosis?

artículo científico publicado en 2005

CNTF inhibits high voltage activated Ca2+ currents in fetal mouse cortical neurones.

artículo científico publicado en 2002

Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia

artículo científico publicado en 2014

Cell membrane patches are supported by proteoglycans ⬇️

artículo científico publicado el 1 de abril de 1995

Cell swelling activates cloned Ca2+-activated K+ channels: a role for the F-actin cytoskeleton

artículo científico publicado en 2003

Chamber-specific effects of hypokalaemia on ventricular arrhythmogenicity in isolated, perfused guinea-pig heart

article

Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase ⬇️

artículo científico publicado el 1 de enero de 1998

Characterization of cardiac repolarization in the Göttingen minipig

artículo científico publicado en 2010

Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current

artículo científico publicado en 2008

Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel.

artículo científico publicado en 1998

Characterization of two new dominant ClC-1 channel mutations associated with myotonia

artículo científico publicado en 2003

Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.

artículo científico publicado en 2007

Chloride-selective channels of large conductance in bovine aortic endothelial cells

artículo científico publicado en 1992

Chronic sympathetic activation promotes downregulation of β-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction

artículo científico publicado en 2011

Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes

artículo científico publicado en 2011

Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model.

artículo científico publicado en 2008

Contribution of Kv7 channels to basal coronary flow and active response to ischemia.

artículo científico publicado en 2013

Coronary vasorelaxant effect of levosimendan, a new inodilator with calcium-sensitizing properties.

artículo científico publicado en 1998

Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

artículo científico publicado en 2012

Development of heart failure is independent of K+ channel-interacting protein 2 expression

artículo científico publicado en 2013

Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

artículo científico publicado en 2009

Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics

artículo científico publicado en 2010

Downregulation of Kv7.4 channel activity in primary and secondary hypertension

artículo científico publicado en 2011

Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes.

artículo científico publicado en 2002

Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels.

artículo científico publicado en 2005

Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.

artículo científico publicado en 2010

Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart.

artículo científico publicado en 2007

Electrical resistance of arterioles and venules in the hamster cheek pouch

scientific article published on 01 January 1985

Electrical resistance of brain microvascular endothelium

artículo científico publicado en 1982

Electrical resistance of muscle capillary endothelium.

artículo científico publicado en 1983

Electrophysiological determinants of hypokalaemia-induced arrhythmogenicity in the guinea-pig heart

artículo científico publicado en 2009

Extracellular Potassium Inhibits Kv7.1 Potassium Channels by Stabilizing an Inactivated State ⬇️

artículo científico publicado el 17 de agosto de 2011

Familial Aggregation of Lone Atrial Fibrillation in Young Persons

Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome

artículo científico publicado en 2005

Functional properties of human neuronal Kv11 channels

artículo científico publicado en 2009

Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone.

artículo científico publicado en 2015

G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

artículo científico publicado en 2013

GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology.

artículo científico publicado en 2013

Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillation

artículo científico publicado en 2014

Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation

artículo científico publicado en 2013

Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

artículo científico publicado en 2013

Haemodynamic shear stress activates a K+ current in vascular endothelial cells.

artículo científico publicado en 1988

High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation

artículo científico publicado en 2012

IKs Gain- and Loss-of-Function in Early-Onset Lone Atrial Fibrillation

scientific journal article

Identification of a Kir3.4 mutation in congenital long QT syndrome

scientific journal article

Identification of a novel voltage-gated Na+ channel rNa(v)1.5a in the rat hippocampal progenitor stem cell line HiB5.

artículo científico publicado en 2001

In vivo effects of the IKr agonist NS3623 on cardiac electrophysiology of the guinea pig.

artículo científico publicado en 2008

Inactivation as a new regulatory mechanism for neuronal Kv7 channels

artículo científico publicado en 2007

K(Ca)3.1 channel downregulation and impaired endothelium-derived hyperpolarization-type relaxation in pulmonary arteries from chronically hypoxic rats

artículo científico publicado en 2012

K(v)7 channels: function, pharmacology and channel modulators.

artículo científico publicado en 2006

KCNE3 is an inhibitory subunit of the Kv4.3 potassium channel

artículo científico publicado en 2006

KCNE3 mutation V17M identified in a patient with lone atrial fibrillation

artículo científico publicado en 2008

KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels

artículo científico publicado en 2003

KCNE4 is an inhibitory subunit to the KCNQ1 channel

artículo científico publicado en 2002

KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current

artículo científico publicado en 2002

KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury

artículo científico publicado en 2014

KCNQ1 channels sense small changes in cell volume

artículo científico publicado en 2003

KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval

artículo científico publicado en 2007

Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

artículo científico publicado en 2011

Kv7.1 surface expression is regulated by epithelial cell polarization ⬇️

artículo científico publicado el 12 de enero de 2011

Leakiness of rat brain microvessels to fluorescent probes following craniotomy

artículo científico publicado en 1987

Live Imaging of Kv7.2/7.3 Cell Surface Dynamics at the Axon Initial Segment: High Steady-State Stability and Calpain-Dependent Excitotoxic Downregulation Revealed.

artículo científico publicado en 2016

Loss of K+ currents in heart failure is accentuated in KChIP2 deficient mice

artículo científico publicado en 2014

Magnetocardiography on an isolated animal heart with a room-temperature optically pumped magnetometer

artículo científico publicado en 2018

Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing.

artículo científico publicado en 2011

Modulation of ERG channels by XE991.

artículo científico publicado en 2007

Modulation of KCNQ4 channel activity by changes in cell volume.

artículo científico publicado en 2004

Modulation of the Ca(2+)-dependent K+ channel, hslo, by the substituted diphenylurea NS 1608, paxilline and internal Ca2+.

artículo científico publicado en 1996

Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats.

artículo científico publicado en 2016

Muscarinic-activated K+ current in bovine aortic endothelial cells

scientific article published on 01 June 1988

Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation

artículo científico publicado en 2011

Mutations in the Kv1.5 channel gene KCNA5 in cardiac arrest patients

artículo científico publicado en 2007

Myocardial structural, contractile and electrophysiological changes in the guinea-pig heart failure model induced by chronic sympathetic activation

article

NS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions.

artículo científico publicado en 2014

Na+ channel distribution and electrophysiological heterogeneities in guinea pig ventricular wall

artículo científico publicado en 2010

Non-invasive detection of animal nerve impulses with an atomic magnetometer operating near quantum limited sensitivity ⬇️

artículo científico publicado en 2016

Numerous Brugada syndrome-associated genetic variants have no effect on J-point elevation, syncope susceptibility, malignant cardiac arrhythmia, and all-cause mortality

artículo científico publicado en 2016

Opening of large-conductance calcium-activated potassium channels by the substituted benzimidazolone NS004.

artículo científico publicado en 1994

Permeabilities of single arterioles and venules in the frog skin: a functional and morphological study.

artículo científico publicado en 1984

Pharmacological activation of IKr impairs conduction in guinea pig hearts.

artículo científico publicado en 2010

Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart

artículo científico publicado en 2007

Pharmacological characterization of small-conductance Ca(2+)-activated K(+) channels stably expressed in HEK 293 cells

artículo científico publicado en 2000

Pharmacological modulation of SK3 channels.

artículo científico publicado en 2001

Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes

artículo científico publicado en 2008

Physiological consequences of transient outward K+ current activation during heart failure in the canine left ventricle.

artículo científico publicado en 2012

Predictive value of electrical restitution in hypokalemia-induced ventricular arrhythmogenicity.

artículo científico publicado en 2009

Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2

artículo científico publicado en 2015

Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking

artículo científico publicado en 2015

Rapid increase in blood-brain barrier permeability during severe hypoxia and metabolic inhibition.

artículo científico publicado en 1986

Rare genetic variants previously associated with congenital forms of long QT syndrome have little or no effect on the QT interval

artículo científico publicado en 2015

Reduced KCNQ4-Encoded Voltage-Dependent Potassium Channel Activity Underlies Impaired β-Adrenoceptor–Mediated Relaxation of Renal Arteries in Hypertension ⬇️

artículo científico publicado el 21 de febrero de 2012

Regulation of ion permeability in frog brain venules. Significance of calcium, cyclic nucleotides and protein kinase C

scientific article published on 01 June 1987

Relaxation of rat resistance arteries by acetylcholine involves a dual mechanism: activation of K+ channels and formation of nitric oxide

scientific article published on 01 June 1997

Requirement of subunit co-assembly and ankyrin-G for M-channel localization at the axon initial segment

artículo científico publicado en 2007

Selective activation of Ca(2+)-dependent K+ channels by novel benzimidazolone.

artículo científico publicado en 1994

Single-copy insertion of transgenes in Caenorhabditis elegans

artículo científico publicado en 2008

Specific sorting and post-Golgi trafficking of dendritic potassium channels in living neurons

artículo científico publicado en 2014

Stable expression of the human large-conductance Ca2+-activated K+ channel alpha- and beta-subunits in HEK293 cells.

artículo científico publicado en 1997

Subcellular localization of the delayed rectifier K(+) channels KCNQ1 and ERG1 in the rat heart

scientific journal article

Substances that rapidly augment ionic conductance of endothelium in cerebral venules.

artículo científico publicado en 1986

Subtype-specific, bi-component inhibition of SK channels by low internal pH.

artículo científico publicado en 2006

Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

artículo científico publicado en 2017

The Ca2+-activated K+ channel of intermediate conductance: a molecular target for novel treatments?

artículo científico publicado en 2001

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

artículo científico publicado en 2007

The KCNQ1 potassium channel: from gene to physiological function

artículo científico publicado en 2005

The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes

scientific journal article

The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels

artículo científico publicado en 2006

The corticosteroid hormone induced factor: a new modulator of KCNQ1 channels?

artículo científico publicado en 2006

The phenotype characteristics of type 13 long QT syndrome with mutation in KCNJ5 (Kir3.4-G387R).

artículo científico publicado en 2013

The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels

artículo científico publicado en 2007

Tissue-specific effects of acetylcholine in the canine heart.

artículo científico publicado en 2013

Trafficking of Kv2.1 Channels to the Axon Initial Segment by a Novel Nonconventional Secretory Pathway.

artículo científico publicado en 2017

Trafficking of the IKs -complex in MDCK cells: site of subunit assembly and determinants of polarized localization

artículo científico publicado en 2013

Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts.

artículo científico publicado en 2009

Vascular smooth muscle contraction is an independent regulator of endothelial nitric oxide production

artículo científico publicado en 1999

Ventricular repolarization time, location of pacing stimulus and current pulse amplitude conspire to determine arrhythmogenicity in mice

artículo científico publicado en 2016

Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A

artículo científico publicado en 2009

Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation

artículo científico publicado en 2013

[Inherited cardiac diseases caused by Nav1.5 sodium channel mutations]

scientific article published on 01 April 2009

[We wish more professional debate about the bibliometric research indicators]

artículo científico publicado en 2010

hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics

artículo científico publicado en 2005

pH-dependent inhibition of K₂P3.1 prolongs atrial refractoriness in whole hearts

artículo científico publicado en 2016

Lista de obras de Søren-Peter Olesen

A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation

A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

A radiolabeled peptide ligand of the hERG channel, [125I]-BeKm-1.

A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome.

AMP-activated protein kinase downregulates Kv7.1 cell surface expression

ATP-dependent closure and reactivation of inward rectifier K+ channels in endothelial cells

Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).

Activation of the human intermediate-conductance Ca(2+)-activated K(+) channel by 1-ethyl-2-benzimidazolinone is strongly Ca(2+)-dependent.

An electrophysiological study of microvascular permeability and its modulation by chemical mediators

Analysis of the Antitumor Activity of Clotrimazole on A375 Human Melanoma Cells

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

BK channel activation by NS11021 decreases excitability and contractility of urinary bladder smooth muscle

BK channel activators and their therapeutic perspectives

BK channel modulators: a comprehensive overview

Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif

Biophysical characterization of the short QT mutation hERG-N588K reveals a mixed gain-and loss-of-function

Blockade of Ca2+-activated K+ channels in T cells: an option for the treatment of multiple sclerosis?

CNTF inhibits high voltage activated Ca2+ currents in fetal mouse cortical neurones.

Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia

Cell membrane patches are supported by proteoglycans ⬇️

Cell swelling activates cloned Ca2+-activated K+ channels: a role for the F-actin cytoskeleton

Chamber-specific effects of hypokalaemia on ventricular arrhythmogenicity in isolated, perfused guinea-pig heart

Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase ⬇️

Characterization of cardiac repolarization in the Göttingen minipig

Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current

Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel.

Characterization of two new dominant ClC-1 channel mutations associated with myotonia

Characterizations of a loss-of-function mutation in the Kir3.4 channel subunit.

Chloride-selective channels of large conductance in bovine aortic endothelial cells

Chronic sympathetic activation promotes downregulation of β-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction

Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes

Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model.

Contribution of Kv7 channels to basal coronary flow and active response to ischemia.

Coronary vasorelaxant effect of levosimendan, a new inodilator with calcium-sensitizing properties.

Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

Development of heart failure is independent of K+ channel-interacting protein 2 expression

Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics

Downregulation of Kv7.4 channel activity in primary and secondary hypertension

Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes.

Effect of beta-adrenoceptor blockers on human ether-a-go-go-related gene (HERG) potassium channels.

Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.

Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart.

Electrical resistance of arterioles and venules in the hamster cheek pouch

Electrical resistance of brain microvascular endothelium

Electrical resistance of muscle capillary endothelium.

Electrophysiological determinants of hypokalaemia-induced arrhythmogenicity in the guinea-pig heart

Extracellular Potassium Inhibits Kv7.1 Potassium Channels by Stabilizing an Inactivated State ⬇️

Familial Aggregation of Lone Atrial Fibrillation in Young Persons

Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome

Functional properties of human neuronal Kv11 channels

Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone.

G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology.

Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillation

Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation

Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

Haemodynamic shear stress activates a K+ current in vascular endothelial cells.

High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation

IKs Gain- and Loss-of-Function in Early-Onset Lone Atrial Fibrillation

Identification of a Kir3.4 mutation in congenital long QT syndrome

Identification of a novel voltage-gated Na+ channel rNa(v)1.5a in the rat hippocampal progenitor stem cell line HiB5.

In vivo effects of the IKr agonist NS3623 on cardiac electrophysiology of the guinea pig.

Inactivation as a new regulatory mechanism for neuronal Kv7 channels

K(Ca)3.1 channel downregulation and impaired endothelium-derived hyperpolarization-type relaxation in pulmonary arteries from chronically hypoxic rats

K(v)7 channels: function, pharmacology and channel modulators.

KCNE3 is an inhibitory subunit of the Kv4.3 potassium channel

KCNE3 mutation V17M identified in a patient with lone atrial fibrillation

KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels

KCNE4 is an inhibitory subunit to the KCNQ1 channel

KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current

KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury

KCNQ1 channels sense small changes in cell volume

KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval

Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

Kv7.1 surface expression is regulated by epithelial cell polarization ⬇️

Leakiness of rat brain microvessels to fluorescent probes following craniotomy

Live Imaging of Kv7.2/7.3 Cell Surface Dynamics at the Axon Initial Segment: High Steady-State Stability and Calpain-Dependent Excitotoxic Downregulation Revealed.