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2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity

scientific article published on 07 July 2019

2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation

artículo científico publicado en 2014

A Novel High-Content Screening-Based Method for Anti- Drug Discovery Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

artículo científico publicado en 2021

Anti-liver cancer activity in vitro and in vivo induced by 2-pyridyl 2,3-thiazole derivatives.

artículo científico publicado en 2017

Antitumor and immunomodulatory activities of thiosemicarbazones and 1,3-Thiazoles in Jurkat and HT-29 cells

artículo científico publicado en 2016

Approaches for the development of new anti-Trypanosoma cruzi agents.

scientific article published on March 2009

Aryl thiosemicarbazones: In vitro and immunomodulatory activities against L. amazonensis

artículo científico publicado en 2017

Compound profiling and 3D-QSAR studies of hydrazone derivatives with activity against intracellular Trypanosoma cruzi.

artículo científico publicado en 2016

Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death

artículo científico publicado en 2014

Cytotoxic and toxicological effects of phthalimide derivatives on tumor and normal murine cells.

artículo científico publicado en 2015

Design, synthesis and biological evaluation of 3-[4-(7-chloro-quinolin-4-yl)-piperazin-1-yl]-propionic acid hydrazones as antiprotozoal agents

artículo científico publicado en 2014

Design, synthesis and cruzain docking of 3-(4-substituted-aryl)-1,2,4-oxadiazole-N-acylhydrazones as anti-Trypanosoma cruzi agents

artículo científico publicado en 2009

Design, synthesis and structure–activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities

artículo científico publicado en 2015

Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death

artículo científico publicado en 2017

Evaluation of the anti-Schistosoma mansoni activity of thiosemicarbazones and thiazoles

artículo científico publicado en 2013

Gastroprotective and ulcer healing effects of essential oil of Hyptis martiusii Benth. (Lamiaceae).

artículo científico publicado en 2014

Genotoxic activity of 3-[3-phenyl-1,2,4-oxadiazol-5-yl] propionic acid and its peptidyl derivatives determined by Ames and SOS response tests

artículo científico publicado en 2005

Halogen atoms in the modern medicinal chemistry: hints for the drug design.

artículo científico publicado en 2010

Improvement of in vivo anticancer and antiangiogenic potential of thalidomide derivatives

artículo científico publicado en 2015

In vitro and in vivo activities of multi-target phtalimido-thiazoles on Schistosomiasis mansoni

artículo científico publicado en 2020

In vitro evaluation of cytotoxicity and leishmanicidal activity of phthalimido-thiazole derivatives

artículo científico publicado en 2017

Isatin derivatives and their antiviral properties against arboviruses, a Review.

artículo científico publicado en 2018

Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues

scientific article published on 14 March 2019

New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi.

artículo científico publicado en 2016

Phthalimido-thiazole as privileged scaffold: activity against immature and adult worms of Schistosoma mansoni

artículo científico publicado en 2018

Phthalimido-thiazoles as building blocks and their effects on the growth and morphology of Trypanosoma cruzi

artículo científico publicado en 2016

Privileged Structures in the design of Potential Drug Candidates for Neglected Diseases

artículo científico publicado en 2017

Repeated-Doses Toxicity Study of the Essential Oil of Hyptis martiusii Benth. (Lamiaceae) in Swiss Mice.

artículo científico publicado en 2013

Ruthenium complexes endowed with potent anti-Trypanosoma cruzi activity: Synthesis, biological characterization and structure-activity relationships.

artículo científico publicado en 2009

Structural Investigation of Anti-Trypanosoma cruzi 2-Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice

artículo científico publicado en 2012

Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi

artículo científico publicado en 2017

Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.

artículo científico publicado en 2013

Structural improvement of new thiazolidinones compounds with antinociceptive activity in experimental chemotherapy-induced painful neuropathy

artículo científico publicado en 2017

Structure-activity relationships of mononuclear metal-thiosemicarbazone complexes endowed with potent antiplasmodial and antiamoebic activities.

artículo científico publicado en 2010

Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents.

artículo científico publicado en 2010

Study of acute oral toxicity of the thiazole derivative N-(1-methyl-2-methyl-pyridine)-N-(p-bromophenylthiazol-2-yl)-hydrazine in a Syrian hamster

artículo científico publicado en 2020

Study of in vitro biological activity of thiazoles on Leishmania (Leishmania) infantum

artículo científico publicado en 2020

Synthesis and antitumour evaluation of peptidyl-like derivatives containing the 1,3-benzodioxole system

artículo científico publicado en 2006

Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain.

artículo científico publicado en 2015

Synthesis of 4'-(2-ferrocenyl)-2,2':6'2''-terpyridine: characterization and antiprotozoal activity of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes

artículo científico publicado en 2014

Synthesis of aminoacyl thiaolidones as potential antitumour agents

artículo científico publicado en 2006

Synthesis, Cruzain docking, and in vitro studies of aryl-4-oxothiazolylhydrazones against Trypanosoma cruzi

artículo científico publicado en 2007

Synthesis, anticancer activity and mechanism of action of new thiazole derivatives

artículo científico publicado en 2017

Synthesis, antitumour and antimicrobial activities of new peptidyl derivatives containing the 1,3-benzodioxole system

artículo científico publicado en 2004

Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi

artículo científico publicado en 2006

Thiosemicarbazones and Phthalyl-Thiazoles compounds exert antiviral activity against yellow fever virus and Saint Louis encephalitis virus

artículo científico publicado en 2017