Lista de obras -

A Potent and Selective Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator Improves Movement in Rodent Models of Parkinson's Disease ⬇️

artículo científico publicado el 11 de julio de 2012

A novel series of metabotropic glutamate receptor 5 negative allosteric modulators based on a 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine core ⬇️

artículo científico publicado el 25 de junio de 2013

ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization

artículo científico publicado en 2012

Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3.

artículo científico publicado en 2002

Adaptation of aequorin functional assay to high throughput screening

artículo científico publicado en 2002

Aequorin-Based Functional Assays for G-Protein-Coupled Receptors, Ion Channels, and Tyrosine Kinase Receptors ⬇️

artículo científico publicado el 1 de enero de 2002

Characterization of an mGluR2/3 Negative Allosteric Modulator in Rodent Models of Depression ⬇️

artículo científico publicado el 1 de diciembre de 2011

Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders

artículo científico publicado en 2014

Discovery of 1,5-disubstituted pyridones: a new class of positive allosteric modulators of the metabotropic glutamate 2 receptor

artículo científico publicado en 2010

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

artículo científico publicado en 2003

Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8

artículo científico publicado en 2003

Lentiviral delivery of a vesicular glutamate transporter 1 (VGLUT1)-targeting short hairpin RNA vector into the mouse hippocampus impairs cognition

artículo científico publicado en 2013

Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies

artículo científico publicado en 2002

Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis.

artículo científico publicado en 2005

New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2): identification and synthesis of N-propyl-8-chloro-6-substituted isoquinolones

artículo científico publicado en 2010

Pharmacological and pharmacokinetic properties of JNJ-40411813, a positive allosteric modulator of the mGlu2 receptor

artículo científico publicado en 2014

Pharmacological characterization of the human P2Y13 receptor

artículo científico publicado en 2003

Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension.

artículo científico publicado en 2003

Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids

artículo científico publicado en 2003

Supersensitivity of human metabotropic glutamate 1a receptor signaling in L929sA cells

artículo científico publicado en 2002

mGluR5 negative allosteric modulators overview: a medicinal chemistry approach towards a series of novel therapeutic agents

artículo científico publicado en 2011

Lista de obras de

A Potent and Selective Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator Improves Movement in Rodent Models of Parkinson's Disease ⬇️

A novel series of metabotropic glutamate receptor 5 negative allosteric modulators based on a 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine core ⬇️

ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization

Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3.

Adaptation of aequorin functional assay to high throughput screening

Aequorin-Based Functional Assays for G-Protein-Coupled Receptors, Ion Channels, and Tyrosine Kinase Receptors ⬇️

Characterization of an mGluR2/3 Negative Allosteric Modulator in Rodent Models of Depression ⬇️

Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders

Discovery of 1,5-disubstituted pyridones: a new class of positive allosteric modulators of the metabotropic glutamate 2 receptor

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8

Lentiviral delivery of a vesicular glutamate transporter 1 (VGLUT1)-targeting short hairpin RNA vector into the mouse hippocampus impairs cognition

Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies

Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis.

New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2): identification and synthesis of N-propyl-8-chloro-6-substituted isoquinolones

Pharmacological and pharmacokinetic properties of JNJ-40411813, a positive allosteric modulator of the mGlu2 receptor

Pharmacological characterization of the human P2Y13 receptor

Serotonin 5-HT(2B) receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension.

Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids

Supersensitivity of human metabotropic glutamate 1a receptor signaling in L929sA cells

mGluR5 negative allosteric modulators overview: a medicinal chemistry approach towards a series of novel therapeutic agents