Lista de obras -

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

artículo científico publicado en 2015

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

artículo científico publicado en 2015

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

artículo científico publicado en 2012

CD4-binding-Site Recognition by VH1-46 Germline-derived HIV-1 Neutralizers.

artículo científico publicado en 2014

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

artículo científico publicado en 2013

Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

artículo científico publicado en 2011

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

artículo científico publicado en 2015

De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts

artículo científico publicado en 2013

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

artículo científico publicado en 2016

Eliminating antibody polyreactivity through addition of N-linked glycosylation

artículo científico publicado en 2015

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

artículo científico publicado en 2014

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

artículo científico publicado en 2011

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

scientific article published on August 2016

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

artículo científico publicado en 2016

Maturation Pathways for the Broad and Potent Antibody 10E8 Using a Combination of Next Generation Sequencing, Bioinformatics and Functional Analysis

artículo científico publicado en 2014

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

artículo científico publicado en 2015

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

artículo científico publicado en 2013

Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

artículo científico publicado en 2016

Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04

artículo científico publicado en 2013

Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera

artículo científico publicado en 2015

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

artículo científico publicado en 2017

Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation

scientific article published in Nature Communications

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

artículo científico publicado en 2015

Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies

artículo científico publicado en 2016

Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6

artículo científico publicado en 2014

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

artículo científico publicado en 2015

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

artículo científico publicado en 2013

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

artículo científico publicado en 2014

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

artículo científico publicado en 2011

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

artículo científico publicado en 2013

Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus

artículo científico publicado en 2016

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

artículo científico publicado en 2016

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

artículo científico publicado en 2016

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

artículo científico publicado en 2016

Lista de obras de

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

CD4-binding-Site Recognition by VH1-46 Germline-derived HIV-1 Neutralizers.

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

Eliminating antibody polyreactivity through addition of N-linked glycosylation

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

Maturation Pathways for the Broad and Potent Antibody 10E8 Using a Combination of Next Generation Sequencing, Bioinformatics and Functional Analysis

Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection

Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies

Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04

Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies

Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses