Lista de obras -

An anti-CD19 antibody inhibits the interaction between P-glycoprotein (P-gp) and CD19, causes P-gp to translocate out of lipid rafts, and chemosensitizes a multidrug-resistant (MDR) lymphoma cell line

artículo científico publicado en 2004

Anti-CD19 antibodies inhibit the function of the P-gp pump in multidrug-resistant B lymphoma cells.

artículo científico publicado en 1999

Anti-CD19 inhibits the growth of human B-cell tumor lines in vitro and of Daudi cells in SCID mice by inducing cell cycle arrest

artículo científico publicado en 1994

Antitumor activity of Fab' and IgG-anti-CD22 immunotoxins in disseminated human B lymphoma grown in mice with severe combined immunodeficiency disease: effect on tumor cells in extranodal sites

artículo científico publicado en 1991

Binding of cytophilic rabbit IgG to homologous hepatocytes ⬇️

artículo científico publicado el 15 de junio de 1979

Combination immunotoxin treatment and chemotherapy in SCID mice with advanced, disseminated Daudi lymphoma

scientific article published on 01 September 1996

Covalent binding of human alpha 2-macroglobulin to deglycosylated ricin A chain and its immunotoxins

artículo científico publicado en 1991

Disseminated or localized growth of a human B-cell tumor (Daudi) in SCID mice

artículo científico publicado en 1990

Effect of sublethal irradiation of SCID mice on growth of B-cell lymphoma xenografts and on efficacy of chemotherapy and/or immunotoxin therapy

scientific article published on 01 June 1996

Eradication of minimal disease in severe combined immunodeficient mice with disseminated Daudi lymphoma using chemotherapy and an immunotoxin cocktail.

artículo científico publicado en 1994

Evaluation of four CD22 antibodies as ricin A chain-containing immunotoxins for the in vivo therapy of human B-cell leukemias and lymphomas

artículo científico publicado en 1988

Evaluation of ricin A chain-containing immunotoxins directed against CD19 and CD22 antigens on normal and malignant human B-cells as potential reagents for in vivo therapy

artículo científico publicado en 1988

Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein

artículo científico publicado en 2008

Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice

scientific article published on 10 March 2003

Homodimerization of tumor-reactive monoclonal antibodies markedly increases their ability to induce growth arrest or apoptosis of tumor cells

artículo científico publicado en 1997

Homodimers but not monomers of Rituxan (chimeric anti-CD20) induce apoptosis in human B-lymphoma cells and synergize with a chemotherapeutic agent and an immunotoxin.

artículo científico publicado en 2001

Immunotoxins for the Treatment of B-Cell Lymphomas ⬇️

artículo científico publicado el 1 de julio de 1997

Interaction between rabbit IgG immune complexes and Ricinus agglutinin

artículo científico publicado en 1986

Isolation of a rabbit IgG fraction with cytophilic properties ⬇️

artículo científico publicado el 13 de mayo de 1983

Large scale preparation of an immunoconjugate constructed with human recombinant CD4 and deglycosylated ricin A chain

artículo científico publicado en 1990

Large scale preparation of immunotoxins constructed with the Fab' fragment of IgG1 murine monoclonal antibodies and chemically deglycosylated ricin A chain

artículo científico publicado en 1988

Preparation and characterization of conjugates of recombinant CD4 and deglycosylated ricin A chain using different cross-linkers

artículo científico publicado en 1990

Protein A vectorized toxins--I. Preparation and properties of protein A-ricin toxin conjugates

artículo científico publicado en 1986

Protein a vectorized toxins—II. Preparation and “in vitro” cytotoxic effect of protein A-ricin a chain conjugate on antibody coated human tumour cells ⬇️

artículo científico publicado el 1 de mayo de 1988

Recent developments in immunotoxin therapy

artículo científico publicado en 1994

Ricin A-chain and ricin A-chain immunotoxins rapidly damage human endothelial cells: implications for vascular leak syndrome

artículo científico publicado en 1993

Rituximab but not other anti-CD20 antibodies reverses multidrug resistance in 2 B lymphoma cell lines, blocks the activity of P-glycoprotein (P-gp), and induces P-gp to translocate out of lipid rafts

artículo científico publicado en 2006

Targeting mammalian target of rapamycin to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines

artículo científico publicado en 2009

Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo.

artículo científico publicado en 2002

The GLP large scale preparation of immunotoxins containing deglycosylated ricin A chain and a hindered disulfide bond

artículo científico publicado en 1991

The antitumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin

artículo científico publicado en 1992

The combined use of an immunotoxin and a radioimmunoconjugate to treat disseminated human B-cell lymphoma in immunodeficient mice

artículo científico publicado en 2000

The epitope specificity and tissue reactivity of four murine monoclonal anti-CD22 antibodies

scientific article published on 01 January 1989

The evaluation of recombinant, chimeric, tetravalent antihuman CD22 antibodies

artículo científico publicado en 2004

Lista de obras de

An anti-CD19 antibody inhibits the interaction between P-glycoprotein (P-gp) and CD19, causes P-gp to translocate out of lipid rafts, and chemosensitizes a multidrug-resistant (MDR) lymphoma cell line

Anti-CD19 antibodies inhibit the function of the P-gp pump in multidrug-resistant B lymphoma cells.

Anti-CD19 inhibits the growth of human B-cell tumor lines in vitro and of Daudi cells in SCID mice by inducing cell cycle arrest

Antitumor activity of Fab' and IgG-anti-CD22 immunotoxins in disseminated human B lymphoma grown in mice with severe combined immunodeficiency disease: effect on tumor cells in extranodal sites

Binding of cytophilic rabbit IgG to homologous hepatocytes ⬇️

Combination immunotoxin treatment and chemotherapy in SCID mice with advanced, disseminated Daudi lymphoma

Covalent binding of human alpha 2-macroglobulin to deglycosylated ricin A chain and its immunotoxins

Disseminated or localized growth of a human B-cell tumor (Daudi) in SCID mice

Effect of sublethal irradiation of SCID mice on growth of B-cell lymphoma xenografts and on efficacy of chemotherapy and/or immunotoxin therapy

Eradication of minimal disease in severe combined immunodeficient mice with disseminated Daudi lymphoma using chemotherapy and an immunotoxin cocktail.

Evaluation of four CD22 antibodies as ricin A chain-containing immunotoxins for the in vivo therapy of human B-cell leukemias and lymphomas

Evaluation of ricin A chain-containing immunotoxins directed against CD19 and CD22 antigens on normal and malignant human B-cells as potential reagents for in vivo therapy

Generation of multidrug resistant lymphoma cell lines stably expressing P-glycoprotein

Genetic engineering of an immunotoxin to eliminate pulmonary vascular leak in mice

Homodimerization of tumor-reactive monoclonal antibodies markedly increases their ability to induce growth arrest or apoptosis of tumor cells

Homodimers but not monomers of Rituxan (chimeric anti-CD20) induce apoptosis in human B-lymphoma cells and synergize with a chemotherapeutic agent and an immunotoxin.

Immunotoxins for the Treatment of B-Cell Lymphomas ⬇️

Interaction between rabbit IgG immune complexes and Ricinus agglutinin

Isolation of a rabbit IgG fraction with cytophilic properties ⬇️

Large scale preparation of an immunoconjugate constructed with human recombinant CD4 and deglycosylated ricin A chain

Large scale preparation of immunotoxins constructed with the Fab' fragment of IgG1 murine monoclonal antibodies and chemically deglycosylated ricin A chain

Preparation and characterization of conjugates of recombinant CD4 and deglycosylated ricin A chain using different cross-linkers

Protein A vectorized toxins--I. Preparation and properties of protein A-ricin toxin conjugates

Protein a vectorized toxins—II. Preparation and “in vitro” cytotoxic effect of protein A-ricin a chain conjugate on antibody coated human tumour cells ⬇️

Recent developments in immunotoxin therapy

Ricin A-chain and ricin A-chain immunotoxins rapidly damage human endothelial cells: implications for vascular leak syndrome

Rituximab but not other anti-CD20 antibodies reverses multidrug resistance in 2 B lymphoma cell lines, blocks the activity of P-glycoprotein (P-gp), and induces P-gp to translocate out of lipid rafts

Targeting mammalian target of rapamycin to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines

Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo.

The GLP large scale preparation of immunotoxins containing deglycosylated ricin A chain and a hindered disulfide bond

The antitumor activity of an anti-CD22 immunotoxin in SCID mice with disseminated Daudi lymphoma is enhanced by either an anti-CD19 antibody or an anti-CD19 immunotoxin

The combined use of an immunotoxin and a radioimmunoconjugate to treat disseminated human B-cell lymphoma in immunodeficient mice

The epitope specificity and tissue reactivity of four murine monoclonal anti-CD22 antibodies

The evaluation of recombinant, chimeric, tetravalent antihuman CD22 antibodies