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Alteration of thioredoxin reductase 1 levels in elucidating cancer etiology

artículo científico publicado en 2010

Analysis of methionine/selenomethionine oxidation and methionine sulfoxide reductase function using methionine-rich proteins and antibodies against their oxidized forms.

artículo científico publicado en 2008

Biosynthesis of selenocysteine on its tRNA in eukaryotes

artículo científico publicado en 2007

Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells

artículo científico publicado en 2010

Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimer's disease.

artículo científico publicado en 2010

Drosophila selenophosphate synthetase 1 regulates vitamin B6 metabolism: prediction and confirmation

artículo científico publicado el 24 de agosto de 2011

Evidence for direct roles of two additional factors, SECp43 and soluble liver antigen, in the selenoprotein synthesis machinery

scientific journal article

Human selenophosphate synthetase 1 has five splice variants with unique interactions, subcellular localizations and expression patterns

artículo científico publicado en 2010

Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase

scientific journal article

Impaired selenoprotein expression in brain triggers striatal neuronal loss leading to co-ordination defects in mice

artículo científico publicado en 2014

Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression

artículo científico publicado en 2014

Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets

scientific journal article

Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development

artículo científico publicado en 2009

MsrB1 (methionine-R-sulfoxide reductase 1) knock-out mice: roles of MsrB1 in redox regulation and identification of a novel selenoprotein form

artículo científico publicado en 2008

Mutation in human selenocysteine transfer RNA selectively disrupts selenoprotein synthesis

artículo científico publicado en 2016

Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration

scientific journal article

Osteo-chondroprogenitor-specific deletion of the selenocysteine tRNA gene, Trsp, leads to chondronecrosis and abnormal skeletal development: a putative model for Kashin-Beck disease

artículo científico publicado en 2009

Regulation of selenoproteins and methionine sulfoxide reductases A and B1 by age, calorie restriction, and dietary selenium in mice.

artículo científico publicado en 2010

Secisbp2 is essential for embryonic development and enhances selenoprotein expression

scientific journal article

SelT, SelW, SelH, and Rdx12: genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family

scientific journal article

Selenium and selenoprotein deficiencies induce widespread pyogranuloma formation in mice, while high levels of dietary selenium decrease liver tumor size driven by TGFα

artículo científico publicado en 2013

Selenophosphate synthetase 2 is essential for selenoprotein biosynthesis

scientific journal article

Selenoproteins are essential for proper keratinocyte function and skin development

artículo científico publicado en 2010

Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression

artículo científico publicado en 2009

Structure and catalytic mechanism of eukaryotic selenocysteine synthase

artículo científico publicado en 2008

Supramolecular complexes mediate selenocysteine incorporation in vivo

scientific journal article

Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication

artículo científico publicado en 2007

The RNA-binding protein Secisbp2 differentially modulates UGA codon reassignment and RNA decay.

artículo científico publicado en 2016