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A guanidine-appended scyllo-inositol derivative AAD-66 enhances brain delivery and ameliorates Alzheimer's phenotypes

artículo científico publicado en 2017

A rapid fluorescence-based assay for classification of iNKT cell activating glycolipids

artículo científico publicado en 2011

Ab InitioConformational Study of 1,2:4,5-Di-O-isopropylidene-myo-inositol

Chemoenzymatic syntheses of carbasugar analogues of nucleoside diphosphate sugars: UDP-carba-Gal, UDP-carba-GlcNAc, UDP-carba-Glc, and GDP-carba-Man

artículo científico publicado en 2009

Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2.

artículo científico publicado en 2004

Design, synthesis, and delivery properties of novel guanidine-containing molecular transporters built on dimeric inositol scaffolds

artículo científico publicado en 2007

Design, synthesis, and membrane-translocation studies of inositol-based transporters

artículo científico publicado en 2006

Divergent syntheses of all possible optically active regioisomers of myo-inositol tris- and tetrakisphosphates

artículo científico publicado en 2002

Divergent syntheses of all stereoisomers of phytosphingosine and their use in the construction of a ceramide library

artículo científico publicado en 2008

Effects of Y132H and F145L substitutions on the activity, azole resistance and spectral properties of Candida albicans sterol 14-demethylase P450 (CYP51): a live example showing the selection of altered P450 through interaction with environmental co

artículo científico publicado en 2005

Elimination of a hydroxyl group in FTY720 dramatically improves the phosphorylation rate.

artículo científico publicado en 2010

Evaluation of synthetic sphingolipid analogs as ligands for peroxisome proliferator-activated receptors

artículo científico publicado en 2009

Evidence supporting two-electron nucleophilic displacement in reactions of unhindered alkyl bromides and iodides with boron and aluminum hydride reducing agents

artículo científico publicado en 1987

Facile syntheses of all possible diastereomers of conduritol and various derivatives of inositol stereoisomers in high enantiopurity from myo-inositol

artículo científico publicado en 2002

Guanidine-Containing Molecular Transporters: Sorbitol-Based Transporters Show High Intracellular Selectivity toward Mitochondria

scholarly article by Kaustabh K. Maiti et al published 3 August 2007 in Angewandte Chemie International Edition

Intracellular and transdermal protein delivery mediated by non-covalent interactions with a synthetic guanidine-rich molecular carrier

artículo científico publicado en 2017

Mitochondrial Affinity of Guanidine-rich Molecular Transporters Built on myo- and scyllo-Inositol Scaffolds: Stereochemistry Dependency

Novel guanidine-containing molecular transporters based on lactose scaffolds: lipophilicity effect on the intracellular organellar selectivity.

artículo científico publicado en 2008

Novel lipidated sorbitol-based molecular transporters for non-viral gene delivery.

artículo científico publicado en 2009

On the contribution of stereochemistry to human ITPK1 specificity: Ins(1,4,5,6)P4 is not a physiologic substrate

artículo científico publicado en 2005

Phytic acid synthesis and vacuolar accumulation in suspension-cultured cells of Catharanthus roseus induced by high concentration of inorganic phosphate and cations

artículo científico publicado en 2005

Preparation and evaluation of BBB-permeable trehalose derivatives as potential therapeutic agents for Huntington's disease

Preparation of a 3'-azido-3'-deoxythymidine (AZT) derivative, which is blood-brain barrier permeable.

artículo científico publicado en 2009

Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase

artículo científico

Recent advances in cell-penetrating, non-peptide molecular carriers

artículo científico publicado en 2007

Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase

artículo científico publicado en 2002

Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1

artículo científico publicado en 2007

Structure-activity relationships of dimethylsphingosine (DMS) derivatives and their effects on intracellular pH and Ca2+ in the U937 monocyte cell line

artículo científico publicado en 2006

Syntheses and biological activities of KRN7000 analogues having aromatic residues in the acyl and backbone chains with varying stereochemistry

artículo científico publicado en 2010

Syntheses of sphingosine-1-phosphate analogues and their interaction with EDG/S1P receptors.

artículo científico publicado en 2004

Syntheses of sphingosine-1-phosphate stereoisomers and analogues and their interaction with EDG receptors

artículo científico publicado en 2003

Synthesis and cellular uptake properties of guanidine-containing molecular transporters built on the sucrose scaffold.

artículo científico publicado en 2009

Synthesis of all stereoisomers of KRN7000, the CD1d-binding NKT cell ligand

artículo científico publicado en 2008

Synthesis of three enantiomeric pairs of scyllo-inositol phosphate and molecular interactions between all possible regioisomers of scyllo-inositol phosphate and inositol 1,4,5-trisphosphate 3-kinase

artículo científico publicado en 2003

The synthesis and biological characterization of a ceramide library

artículo científico publicado en 2002

Theoretical Studies of Regioselectivity ofmyo-Inositol Derivatives: Importance of Solvent Dielectric Constants

Vaccinia-related kinase 2 mediates accumulation of polyglutamine aggregates via negative regulation of the chaperonin TRiC.

scientific article published on 02 December 2013