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Lista de obras de Seppo Ylä-Herttuala

(Strept)avidin-displaying lentiviruses as versatile tools for targeting and dual imaging of gene delivery

artículo científico publicado en 2009

10-year safety follow-up in patients with local VEGF gene transfer to ischemic lower limb

artículo científico publicado en 2011

14q32 miRNA Cluster Takes Center Stage in Neovascularization

artículo científico publicado en 2014

15-Lipoxygenase-1 induces lipid peroxidation and apoptosis, and improves survival in rat malignant glioma

artículo científico publicado el 1 de enero de 2012

15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expr

artículo científico publicado en 2007

18-kDa translocator protein ligand 18F-FEMPA: Biodistribution and uptake into atherosclerotic plaques in mice

artículo científico publicado en 2016

1H MR spectroscopic imaging of phospholipase-mediated membrane lipid release in apoptotic rat glioma in vivo

artículo científico publicado en 2008

1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis.

artículo científico publicado en 1999

6-o- and N-sulfated syndecan-1 promotes baculovirus binding and entry into Mammalian cells

scientific article published on 07 August 2013

68Ga-DOTA-RGD peptide: biodistribution and binding into atherosclerotic plaques in mice

artículo científico publicado en 2009

A 96-well format for a high-throughput baculovirus generation, fast titering and recombinant protein production in insect and mammalian cells

artículo científico publicado en 2009

A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus

artículo científico publicado en 2014

A highly reproducible xenograft model for human ovarian carcinoma and application of MRI and ultrasound in longitudinal follow-up

artículo científico publicado en 2006

A model for gene therapy of human hereditary lymphedema

artículo científico publicado en 2001

A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo

artículo científico publicado en 2005

A preclinical assessment of the safety and biodistribution of an adenoviral vector containing the herpes simplex virus thymidine kinase gene (Cerepro) after intracerebral administration

artículo científico publicado en 2009

A stable bis-allyloxycarbonyl biotin aldehyde derivative for biotinylation via reductive alkylation: application to the synthesis of a biotinylated doxorubicin derivative

artículo científico publicado en 2003

AAV9-mediated VEGF-B gene transfer improves systolic function in progressive left ventricular hypertrophy

artículo científico publicado en 2012

ADA-SCID Gene Therapy Endorsed By European Medicines Agency For Marketing Authorization

artículo científico publicado en 2016

ADVANCES AND CHALLENGES IN CARDIOVASCULAR GENE THERAPY.

artículo científico

ASGCT Annual Meeting 2019

artículo científico publicado en 2019

Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle

artículo científico publicado en 2009

Activating the Chromatin by Noncoding RNAs

artículo científico publicado en 2017

Activation of Peroxisome Proliferator-Activated Receptor-δ as Novel Therapeutic Strategy to Prevent In-Stent Restenosis and Stent Thrombosis

artículo científico publicado en 2016

Acute infections in children are accompanied by oxidative modification of LDL and decrease of HDL cholesterol, and are followed by thickening of carotid intima-media

artículo científico publicado en 2003

Acute respiratory viral infections aggravate arterial endothelial dysfunction in children with type 1 diabetes

artículo científico publicado en 2004

AdVEGF-B186 and AdVEGF-DΔNΔC induce angiogenesis and increase perfusion in porcine myocardium

artículo científico publicado en 2016

Adeno-associated virus-mediated gene transfer of a secreted decoy human macrophage scavenger receptor reduces atherosclerotic lesion formation in LDL receptor knockout mice

artículo científico publicado en 2003

Adenoviral VEGF-A gene transfer induces angiogenesis and promotes bone formation in healing osseous tissues

artículo científico publicado en 2003

Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes

artículo científico publicado en 2002

Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart

artículo científico publicado en 2004

Adenoviral expression of 15-lipoxygenase-1 in rabbit aortic endothelium: role in arachidonic acid-induced relaxation

article

Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up

artículo científico publicado en 2017

Adenovirus mediated herpes simplex virus-thymidine kinase/ganciclovir gene therapy for resectable malignant glioma

artículo científico publicado en 2009

Adenovirus-Mediated Gene Transfer of Placental Growth Factor to Perivascular Tissue Induces Angiogenesis via Upregulation of the Expression of Endogenous Vascular Endothelial Growth Factor-A

article

Adenovirus-Mediated Gene Transfer to Lower Limb Artery of Patients with Chronic Critical Leg Ischemia

artículo científico publicado el 1 de julio de 1998

Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloon-denuded rabbit aorta

artículo científico publicado en 2002

Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial

artículo científico publicado en 2013

Adenovirus-mediated gene transfer into an experimental pancreatic tumour.

artículo científico publicado en 2000

Adenovirus-mediated gene transfer of Lp-PLA2 reduces LDL degradation and foam cell formation in vitro

artículo científico publicado en 2004

Adenovirus-mediated gene transfer of a secreted decoy human macrophage scavenger receptor (SR-AI) in LDL receptor knock-out mice

Adenovirus-mediated gene transfer of a secreted form of human macrophage scavenger receptor inhibits modified low-density lipoprotein degradation and foam-cell formation in macrophages

artículo científico publicado en 2000

Adenovirus-mediated gene transfer of human vascular endothelial growth factor-d induces transient angiogenic effects in mouse hind limb muscle

article

Adenovirus-mediated herpes simplex virus thymidine kinase gene therapy in BT4C rat glioma model

artículo científico publicado en 2002

Adenovirus‐mediated VEGF‐A gene transfer induces bone formationin vivo

artículo científico publicado el 8 de abril de 2003

AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study

artículo científico publicado en 2004

Adventitial VEGF165 gene transfer prevents lumen loss through induction of positive arterial remodeling after PTCA in porcine coronary arteries

artículo científico publicado en 2006

Adventitial gene transfer of VEGFR-2 specific VEGF-E chimera induces MCP-1 expression in vascular smooth muscle cells and enhances neointimal formation

artículo científico publicado en 2011

Adventitial gene transfer to arterial wall

artículo científico publicado en 1998

All Eyes and Ears for Gene Therapy

artículo científico publicado en 2018

Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography.

artículo científico publicado en 2018

Amyloid-Targeting PET Tracer [F]Flutemetamol Accumulates in Atherosclerotic Plaques

scientific article published on 19 March 2019

An Efficient Faint Object Spectrograph

artículo científico publicado en 1998

An update on angiogenic gene therapy: vascular endothelial growth factor and other directions.

artículo científico publicado en 2006

Analysis of fat graft metabolic adaptation and vascularization using positron emission tomography-computed tomographic imaging

artículo científico publicado en 2014

Analysis of gene and protein expression during monocyte-macrophage differentiation and cholesterol loading—cDNA and protein array study

article

Angiogenesis, Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor-BB Expression, Iron Deposition, and Oxidation-Specific Epitopes in Stented Human Coronary Arteries

artículo científico publicado el 1 de noviembre de 2001

Angiogenesis-Dependent and Independent Phases of Intimal Hyperplasia

artículo científico publicado en 2004

Angiogenic Responses of Vascular Endothelial Growth Factors in Periadventitial Tissue

article

Angiogenic gene therapy in cardiovascular diseases: dream or vision?

artículo científico publicado en 2017

Angiographically guided utero-placental gene transfer in rabbits with adenoviruses, plasmid/liposomes and plasmid/polyethyleneimine complexes

artículo científico publicado en 2001

Angiopoietin-1 Protects Against the Development of Cardiac Allograft Arteriosclerosis

article

Angiopoietin-1 promotes lymphatic sprouting and hyperplasia.

artículo científico publicado en 2005

Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice

artículo científico publicado en 2015

Angiopoietin-regulated recruitment of vascular smooth muscle cells by endothelial-derived heparin binding EGF-like growth factor

artículo científico publicado en 2003

Animal Models of Gene Therapy for Cardiovascular Disease

article

Animal models of diabetic macrovascular complications: key players in the development of new therapeutic approaches

artículo científico publicado en 2015

Antegrade flow and peripheral resistance determine the level of endogenous arteriogenesis in patients with superficial femoral artery occlusion

artículo científico publicado en 2009

Antiangiogenic gene therapy with soluble VEGF-receptors -1, -2 and -3 together with paclitaxel prolongs survival of mice with human ovarian carcinoma

artículo científico publicado en 2012

Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice

artículo científico publicado en 2008

Antibodies against oxidized LDL and cardiolipin and mortality in patients with coronary heart disease

artículo científico publicado en 2005

Antibody reactivity to an Epstein-Barr virus BERF4-encoded epitope occurring also in Asp-57 region of HLA-DQ8 beta chain. Childhood Diabetes in Finland Study Group.

artículo científico publicado en 1994

Antioxidant gene therapy for cardiovascular disease: current status and future perspectives

scientific article published on April 2008

Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

artículo científico publicado en 1990

Apolipoprotein A-I mimetic peptide 4F blocks sphingomyelinase-induced LDL aggregation

artículo científico publicado en 2015

Apolipoprotein E and colon cancer

artículo científico publicado en 2002

Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

artículo científico publicado en 2013

Artifact occurring during combined in situ hybridization and immunocytochemistry analysis because of positive chemography

scientific article published on 01 May 1998

Assessment of myocardial viability with [15O]water PET: A validation study in experimental myocardial infarction

artículo científico publicado en 2019

Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death

artículo científico publicado en 2003

Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects

artículo científico publicado en 2003

Atherosclerosis and biochemical composition of coronary arteries in Finnish men Comparison of two populations with different incidences of coronary heart disease

article

Autoantibodies against oxidized LDL and endothelium-dependent vasodilation in insulin-dependent diabetes mellitus

artículo científico publicado en 1999

Autoantibodies against oxidized LDL are associated with severe chest pain attacks in patients with coronary heart disease

artículo científico publicado en 2005

Autoantibodies against oxidized LDL do not predict atherosclerotic vascular disease in non-insulin-dependent diabetes mellitus

artículo científico publicado en 1996

Autoantibodies against oxidized low density lipoprotein in patients with angiographically verified coronary artery disease

artículo científico publicado en 1999

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

artículo científico publicado en 1992

Avidin Fusion Protein Strategies in Targeted Drug and Gene Delivery

article

Avidin fusion protein-expressing lentiviral vector for targeted drug delivery.

artículo científico publicado en 2009

Avidin-biotin technology in targeted therapy

artículo científico publicado en 2010

Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function

scientific article published on 12 March 2019

BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF

artículo científico publicado en 2020

Baculovirus capsid display: a novel tool for transduction imaging

artículo científico publicado en 2003

Baculovirus is an efficient vector for the transduction of the eye: comparison of baculovirus- and adenovirus-mediated intravitreal vascular endothelial growth factor D gene transfer in the rabbit eye.

artículo científico publicado en 2009

Baculovirus-mediated gene delivery and RNAi applications

artículo científico

Baculovirus-mediated immediate-early gene expression and nuclear reorganization in human cells

artículo científico publicado en 2007

Baculovirus-mediated periadventitial gene transfer to rabbit carotid artery

artículo científico publicado en 2000

Baculovirus-mediated vascular endothelial growth factor-D(ΔNΔC) gene transfer induces angiogenesis in rabbit skeletal muscle

artículo científico publicado en 2012

Baculovirus: an insect-derived vector for diverse gene transfer applications

artículo científico publicado en 2013

Baculoviruses exhibit restricted cell type specificity in rat brain: a comparison of baculovirus- and adenovirus-mediated intracerebral gene transfer in vivo

artículo científico publicado en 2002

Baculoviruses mediate efficient gene expression in a wide range of vertebrate cells

artículo científico publicado en 2011

Baseline diene conjugation in LDL lipids as a direct measure of in vivo LDL oxidation

artículo científico publicado en 1998

Beta-galactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses

artículo científico publicado en 1998

Beyond endothelial cells: Vascular endothelial growth factors in heart, vascular anomalies and placenta

artículo científico publicado en 2018

Bile-duct proliferation as an unexpected side-effect after AAV2-LDLR gene transfer to rabbit liver

article

Biochemical composition of human internal mammary artery and saphenous vein

article

Biodegradable coronary scaffolds: their future and clinical and technological challenges

artículo científico publicado en 2018

Biodistribution and antitumor effect of Cetuximab-targeted lentivirus

artículo científico publicado en 2013

Biodistribution of adenoviral vector to nontarget tissues after local in vivo gene transfer to arterial wall using intravascular and periadventitial gene delivery methods

artículo científico publicado en 2000

Biology of vascular endothelial growth factors

artículo científico publicado en 2006

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

artículo científico publicado en 2008

Blood flow remodels growing vasculature during vascular endothelial growth factor gene therapy and determines between capillary arterialization and sprouting angiogenesis

artículo científico publicado en 2005

Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth

artículo científico publicado en 2008

Brain pharmacokinetics of ganciclovir in rats with orthotopic BT4C glioma

artículo científico publicado en 2014

Bumps in the Road for Commercial Gene Therapy for Rare Diseases

artículo científico publicado en 2017

CRISPR/Cas9 and p53: An Odd Couple Requiring Relationship Management

scientific article published on 16 November 2018

Call for papers: Nanoparticle Development and Applications in Cellular and Molecular Therapies

artículo científico publicado en 2016

Cancer gene therapy — current status in the clinics

Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy

artículo científico publicado en 2010

Cardiac Lymphatics - A New Avenue for Therapeutics?

artículo científico publicado en 2017

CardioPulse: Progress in gene therapy for cardiovascular disease

artículo científico publicado en 2016

Cardiovascular Gene Therapy: Past, Present, and Future

artículo científico publicado en 2017

Cardiovascular gene therapy with vascular endothelial growth factors

artículo científico publicado en 2013

Catheter-mediated vascular endothelial growth factor gene transfer to human coronary arteries after angioplasty

artículo científico publicado en 2000

Cell susceptibility to baculovirus transduction and echovirus infection is modified by protein kinase C phosphorylation and vimentin organization

artículo científico publicado en 2013

Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells

artículo científico publicado en 2002

Cerivastatin and hypercholesterolemia reduce apoptosis of cardiomyocytes in guinea pig papillary muscle subjected to hypoxia/reoxygenation

scientific article published on 01 May 2006

Challenges in monoclonal antibody-based therapies

artículo científico publicado en 2009

Changes in gene expression in atherosclerotic plaques analyzed using DNA array

article

Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress

scientific article published on 17 July 2019

Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis

artículo científico publicado en 2021

Characterization of atherosclerotic lesions in apo E3-leiden transgenic mice

artículo científico publicado en 1998

Characterizing atherosclerotic lesions by in-plane ultrasonic TOF measurements

Clathrin-independent entry of baculovirus triggers uptake of E. coli in non-phagocytic human cells

artículo científico publicado en 2009

Clinical applications of vascular gene therapy

artículo científico publicado en 2001

Clinical significance of apoptotic index in non-small cell lung cancer: correlation with p53, mdm2, pRb and p21WAF1/CIP1 protein expression

artículo científico publicado en 2005

Clinical trials for glioblastoma multiforme using adenoviral vectors.

artículo científico publicado en 2009

Clonal variation in interferon response determines the outcome of oncolytic virotherapy in mouse CT26 colon carcinoma model.

artículo científico publicado en 2014

Cloning and characterization of Scavidin, a fusion protein for the targeted delivery of biotinylated molecules

artículo científico publicado en 2001

Cloning and characterization of soluble decoy receptors

artículo científico publicado en 2002

Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis

scientific article published on 03 December 2018

Co-infection with Chlamydia pneumoniae and Helicobacter pylori results in vascular endothelial dysfunction and enhanced VCAM-1 expression in apoE-knockout mice

scientific article published on March 2003

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions

artículo científico publicado el 1 de septiembre de 1990

Combined Gene Therapy Using AdsVEGFR2 and AdsTie2 With Chemotherapy Reduces the Growth of Human Ovarian Cancer and Formation of Ascites in Mice

artículo científico publicado en 2017

Combined vascular endothelial growth factor-A and fibroblast growth factor 4 gene transfer improves wound healing in diabetic mice

artículo científico publicado en 2010

Comparative Study Of Adeno-Associated Virus, Adenovirus, Baculovirus And Lentivirus Vectors For Gene Therapy Of The Eyes

artículo científico publicado en 2017

Comparison of different ways of presenting the results of biochemical analyses of human coronary arteries

artículo científico publicado en 1986

Comparison of the effects of alpha-tocopherol, ubiquinone-10 and probucol at therapeutic doses on atherosclerosis in WHHL rabbits

artículo científico publicado en 2002

Complement and anti-alpha-galactosyl natural antibody-mediated inactivation of murine retrovirus occurs in adult serum but not in umbilical cord serum

artículo científico publicado en 1999

Computed tomographic coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE HF Project 1-C).

artículo científico publicado en 2013

Conditional expression of Lodavin, an avidin-tagged LDL receptor, for biotin-mediated applications in vivo

artículo científico publicado en 2012

Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China

article

Consensus guidelines for the use and interpretation of angiogenesis assays

article

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization

artículo científico publicado en 2014

Corrigendum to “Non-invasive Imaging in Gene Therapy”

article

Corrigendum to “Primary effect of 1α,25(OH)2D3 on IL-10 expression in monocytes is short-term down-regulation” [Biochim. Biophys. Acta 1803 (2010) 1276–86]

scholarly article by Juha M. Matilainen published in December 2011

Cotargeting of VEGFR-1 and -3 and angiopoietin receptor Tie2 reduces the growth of solid human ovarian cancer in mice

artículo científico publicado en 2010

Critical role of VEGF-C/VEGFR-3 signaling in innate and adaptive immune responses in experimental obliterative bronchiolitis

artículo científico publicado en 2012

Culture medium induced vimentin reorganization associates with enhanced baculovirus-mediated gene delivery

Current gene therapy trials for vascular diseases

artículo científico

Current status of cardiovascular gene therapy

artículo científico publicado en 2007

Cytochrome P450 2A5 constitutive expression and induction by heavy metals is dependent on redox-sensitive transcription factor Nrf2 in liver

artículo científico publicado en 2010

DNA hypomethylation and methyltransferase expression in atherosclerotic lesions

artículo científico publicado en 2002

DNA methylation processes in atheosclerotic plaque

scientific article published on 18 December 2018

DNA methylation, smooth muscle cells, and atherogenesis

artículo científico publicado en 2003

Debate on Germline Gene Editing

artículo científico publicado en 2016

Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis

artículo científico publicado en 2004

Deletion of Lymphangiogenic and Angiogenic Growth Factor VEGF-D Leads to Severe Hyperlipidemia and Delayed Clearance of Chylomicron Remnants

artículo científico publicado en 2018

Detection of Hypoxia by [ 18 F]EF5 in Atherosclerotic Plaques in Mice

Development of Lentiviral Vectors for Targeted Integration and Protein Delivery

artículo científico publicado en 2016

Development of Safe and Efficient Viral Vectors for Clinical Gene Therapy

Diet intervention reduces uptake of αvβ3 integrin-targeted PET tracer 18F-galacto-RGD in mouse atherosclerotic plaques

article by Antti Saraste et al published 20 April 2012 in Journal of Nuclear Cardiology

Dietary (n-3) fatty acids reduce plasma F2-isoprostanes but not prostaglandin F2alpha in healthy humans

artículo científico publicado en 2006

Differences in retinal neovascular tissue and vitreous humour in patients with type 1 and type 2 diabetes

artículo científico publicado en 2009

Different apolipoprotein B breakdown patterns in models of oxidized low density lipoprotein

artículo científico publicado en 1999

Differential Promoter Methylation of Macrophage Genes Is Associated With Impaired Vascular Growth in Ischemic Muscles of Hyperlipidemic and Type 2 Diabetic Mice: Genome-Wide Promoter Methylation Study

artículo científico publicado en 2015

Differential Regulation of Vascular Endothelial Growth Factors by Promoter-targeted shRNAs

artículo científico publicado en 2015

Differential but Complementary HIF1α and HIF2α Transcriptional Regulation

artículo científico publicado en 2018

Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8.

artículo científico publicado en 2016

Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins

artículo científico publicado en 2007

Distinct metabolic and vascular effects of dietary triglycerides and cholesterol in atherosclerotic and diabetic mouse models

artículo científico publicado en 2013

Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting.

artículo científico publicado en 2007

Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits

artículo científico publicado en 1990

Does Nrf2 gene transfer facilitate recovery after contusion spinal cord injury?

artículo científico publicado en 2013

Does mass balance between sense and antisense transcripts fine-tune the outcome of gene expression?

artículo científico publicado en 2014

Dotted collar placed around carotid artery induces asymmetric neointimal lesion formation in rabbits without intravascular manipulations

artículo científico publicado en 2012

Down's syndrome and atherosclerosis

artículo científico publicado en 1989

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction

artículo científico publicado en 2018

Doxycycline modulates VEGF-A expression: Failure of doxycycline-inducible lentivirus shRNA vector to knockdown VEGF-A expression in transgenic mice

artículo científico publicado en 2018

Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo

artículo científico publicado en 2003

Dual role of vascular endothelial growth factor in experimental obliterative bronchiolitis.

artículo científico publicado en 2005

EC-SOD gene therapy reduces paracetamol-induced liver damage in mice

artículo científico publicado en 2001

ESGCT 2017 in Berlin: Clear Steps Forward

artículo científico publicado en 2017

Early gene therapy-induced apoptotic response in BT4C gliomas by magnetic resonance relaxation contrast T1 in the rotating frame

artículo científico publicado en 2002

Editorial: Vascularization for Regenerative Medicine

artículo científico publicado en 2018

Effect of adventitial VEGF(165) gene transfer on vascular thickening after coronary artery balloon injury

artículo científico publicado en 2003

Effect of post-mortem time on the biochemical composition of coronary arteries

artículo científico publicado en 1985

Effect of repeated endotoxin treatment and hypercholesterolemia on preatherosclerotic lesions in weaned pigs Part 1. Scanning and transmission electron microscopic study

article

Effect of repeated endotoxin treatment and hypercholesterolemia on preatherosclerotic lesions in weaned pigs Part 11. Lipid and glycosaminoglycan analysis of intima and inner media

Effect of vitamin E on endothelial vasodilator function in patients with hypercholesterolemia, chronic smoking or both

artículo científico publicado en 1999

Effects of Age, Diet, and Type 2 Diabetes on the Development and FDG Uptake of Atherosclerotic Plaques

article

Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis

artículo científico publicado en 2012

Effects of atorvastatin and diet interventions on atherosclerotic plaque inflammation and [ 18 F]FDG uptake in Ldlr −/− Apob 100/100 mice

Effects of linagliptin intervention on atherosclerotic plaque inflammation and 18F-FDG uptake in a mouse model of type 2 diabetes

Effects of liposome-encapsulated bisphosphonates on acetylated LDL metabolism, lipid accumulation and viability of phagocyting cells

artículo científico publicado en 1998

Effects of vaccinia virus anti-inflammatory protein 35K and TIMP-1 gene transfers on vein graft stenosis in rabbits

artículo científico publicado en 2005

Efficacy and safety of myocardial gene transfer of adenovirus, adeno-associated virus and lentivirus vectors in the mouse heart

artículo científico publicado en 2015

Efficient adventitial gene delivery to rabbit carotid artery with cationic polymer-plasmid complexes

artículo científico publicado en 1999

Efficient gene therapy based targeting system for the treatment of inoperable tumors

artículo científico publicado en 2012

Efficient pro-survival/angiogenic miRNA delivery by an MRI-detectable nanomaterial.

artículo científico publicado en 2013

Efficient production of active chicken avidin using a bacterial signal peptide in Escherichia coli

artículo científico publicado en 2004

Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy

artículo científico publicado en 2009

Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer

artículo científico publicado en 2009

Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism

artículo científico publicado en 2011

Endgame: glybera finally recommended for approval as the first gene therapy drug in the European union

artículo científico publicado en 2012

Endostatin inhibits endochondral ossification

scholarly article by A Sipola published in January 2007

Endothelial 15-lipoxygenase-1 overexpression increases acetylcholine-induced hypotension and vasorelaxation in rabbits

artículo científico publicado en 2008

Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat

scientific article published on 05 August 2016

Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions.

artículo científico publicado en 2017

Endothelium-specific overexpression of human vascular endothelial growth factor-D in mice leads to increased tumor frequency and a reduced lifespan

artículo científico publicado en 2012

Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein

artículo científico publicado en 2007

Enhanced gene delivery by avidin-displaying baculovirus

artículo científico publicado en 2004

Enhanced plasma cholesterol lowering effect of retrovirus-mediated LDL receptor gene transfer to WHHL rabbit liver after improved surgical technique and stimulation of hepatocyte proliferation by combined partial liver resection and thymidine kinase

artículo científico publicado en 1999

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

artículo científico publicado en 2007

Enhancing Angiogenesis in Mice by VEGF-Targeting Small Activating RNAs

artículo científico

Enrichment of long-chain ω9 and ω6 fatty acids in arterial cholesteryl esters in the early phase of atherogenesis

Enterolactone induces heme oxygenase-1 expression through nuclear factor-E2-related factor 2 activation in endothelial cells.

artículo científico publicado en 2008

EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF.

artículo científico publicado en 2018

Epigenetherapy, a new concept

artículo científico publicado en 2011

Epigenetic Epidemiology of Atherosclerosis

scholarly article published 1 November 2011

Epigenetic regulation in vascular cells

artículo científico

Epigenetic regulation of key vascular genes and growth factors

artículo científico publicado en 2011

Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice

artículo científico publicado en 2014

Epigenetics and Atherosclerosis

article published in 2012

Epigenetics and atherosclerosis

artículo científico publicado en 2009

Epigenetics and atherosclerosis

Erratum: Long-term VEGF-A expression promotes aberrant angiogenesis and fibrosis in skeletal muscle

scholarly article published in Gene Therapy

Erratum: Periadventitial angiopoietin 1 gene transfer induces angiogenesis in rabbit carotid arteries

article

Escherichia coli DNA contamination in AmpliTaq Gold polymerase interferes with TaqMan analysis of lacZ.

artículo científico publicado en 2002

Evaluation and characterization of EIA measuring autoantibodies against oxidized LDL

artículo científico publicado en 2001

Evaluation of alphavbeta3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice

artículo científico publicado en 2009

Evaluation of angiogenesis and side effects in ischemic rabbit hindlimbs after intramuscular injection of adenoviral vectors encoding VEGF and LacZ.

artículo científico publicado en 2002

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man

artículo científico publicado en 1989

Evolving revascularization approaches for myocardial ischemia

artículo científico publicado en 2003

Exosomes as secondary inductive signals involved in kidney organogenesis

artículo científico publicado en 2018

Experimental hyperlipidaemia does not prevent preconditioning and it reduces ischemia-induced apoptosis.

artículo científico publicado en 2007

Expression of LDL receptor, VLDL receptor, LDL receptor-related protein, and scavenger receptor in rabbit atherosclerotic lesions: marked induction of scavenger receptor and VLDL receptor expression during lesion development

artículo científico publicado en 1998

Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and scavenger receptor in human atherosclerotic lesions

artículo científico publicado en 1994

Expression of extracellular SOD and iNOS in macrophages and smooth muscle cells in human and rabbit atherosclerotic lesions: colocalization with epitopes characteristic of oxidized LDL and peroxynitrite-modified proteins.

artículo científico publicado en 1998

Expression of inducible nitric oxide synthase in macrophages and smooth muscle cells in various types of human atherosclerotic lesions

artículo científico publicado en 1999

Expression of lipoprotein receptors in atherosclerotic lesions

artículo científico publicado el 1 de abril de 1998

Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions

artículo científico publicado en 1991

Expression of urokinase-type plasminogen activator receptor is increased during epileptogenesis in the rat hippocampus.

artículo científico publicado en 2009

Expression of vascular endothelial growth factor (VEGF)-B and its receptor (VEGFR1) in murine heart, lung and kidney

artículo científico publicado en 2016

Expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in ischemic skeletal muscle and its regeneration

artículo científico publicado en 2002

Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer.

artículo científico publicado en 2019

Extended release of adenovirus from silica implants in vitro and in vivo

artículo científico publicado en 2008

Extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta.

artículo científico publicado en 2007

Extracellular superoxide dismutase deficiency and atherosclerosis in mice

artículo científico publicado en 2001

Extracellular superoxide dismutase with vaccinia virus anti-inflammatory protein 35K or tissue inhibitor of metalloproteinase-1: Combination gene therapy in the treatment of vein graft stenosis in rabbits

artículo científico publicado en 2006

Extracellular vesicles provide a capsid-free vector for oncolytic adenoviral DNA delivery

artículo científico publicado en 2020

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

artículo científico publicado en 2009

False-positive apoptosis signal in mouse kidney and liver detected with TUNEL assay

artículo científico publicado en 2000

Feasibility of experimental BT4C glioma models for somatostatin receptor 2-targeted therapies

artículo científico publicado en 2014

Feline immunodeficiency virus and retrovirus-mediated adventitial ex vivo gene transfer to rabbit carotid artery using autologous vascular smooth muscle cells

artículo científico publicado en 2004

Fetal membranes act as a barrier for adenoviruses: gene transfer into exocoelomic cavity of rat fetuses does not affect cells in the fetus

artículo científico publicado en 2004

Fibroblast growth factor 4 induces vascular permeability, angiogenesis and arteriogenesis in a rabbit hindlimb ischemia model

artículo científico publicado en 2002

From the impact factor to DORA and the scientific content of articles

artículo científico publicado en 2015

Functional genomics and DNA array techniques in atherosclerosis research

artículo científico publicado en 1999

Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology

article

Future prospects and challenges of antiangiogenic cancer gene therapy

artículo científico publicado en 2010

Gamma-secretase inhibitor treatment promotes VEGF-A-driven blood vessel growth and vascular leakage but disrupts neovascular perfusion

artículo científico publicado en 2011

Gene Deliver y to Rabbit Arteries Using the Collar Model

artículo científico publicado el 1 de enero de 1999

Gene Editing of Human Embryos with CRISPR/Cas9: Great Promise Coupled with Important Caveats

artículo científico publicado en 2018

Gene Expression in Macrophage-Rich Inflammatory Cell Infiltrates in Human Atherosclerotic Lesions as Studied by Laser Microdissection and DNA Array

article

Gene Therapy Moves Forward in 2010

artículo científico publicado el 1 de febrero de 2011

Gene Therapy Used in Cancer Treatment

artículo científico publicado en 2014

Gene Therapy for Heart Failure: Back to the Bench

artículo científico publicado en 2015

Gene Therapy in Nordic Countries

artículo científico publicado en 2015

Gene and Cell Therapy: Success Stories and Future Challenges

scientific article published on 19 April 2019

Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes

artículo científico publicado en 2000

Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts

artículo científico publicado en 1991

Gene therapy for angiogenesis, restenosis and related diseases.

artículo científico publicado en 1999

Gene therapy for cardiovascular diseases

artículo científico publicado en 2004

Gene therapy for coronary heart disease

artículo científico publicado en 2001

Gene therapy for ischemic cardiovascular diseases: some lessons learned from the first clinical trials

artículo científico publicado en 2004

Gene therapy for malignant glioma: current clinical status

artículo científico publicado en 2005

Gene therapy for restenosis: current status

artículo científico publicado en 2002

Gene therapy for therapeutic angiogenesis in critically ischaemic lower limb - on the way to the clinic

artículo científico publicado en 2001

Gene therapy in age related macular degeneration and hereditary macular disorders

artículo científico

Gene therapy methods in cardiovascular diseases

artículo científico publicado en 2002

Gene therapy to prevent occlusion of venous bypass grafts

artículo científico publicado en 2008

Gene therapy with vascular endothelial growth factors

artículo científico publicado en 2009

Gene therapy: the first approved gene-based medicines, molecular mechanisms and clinical indications

artículo científico publicado en 2008

Gene transfer as a tool to induce therapeutic vascular growth

artículo científico publicado en 2003

Gene transfer for therapeutic vascular growth in myocardial and peripheral ischemia

artículo científico publicado en 2004

Gene transfer into rabbit arteries with adeno-associated virus and adenovirus vectors.

artículo científico publicado en 2004

Gene transfer into the carotid artery using an adventitial collar: comparison of the effectiveness of the plasmid-liposome complexes, retroviruses, pseudotyped retroviruses, and adenoviruses

artículo científico publicado en 1997

Gene transfer of extracellular superoxide dismutase to atherosclerotic mice

artículo científico publicado en 2001

Gene transfer to human placenta ex vivo: a novel application of dual perfusion of human placental cotyledon

article

Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanism

artículo científico publicado en 2005

Gene transfer vectors (DNA vehicles) and their incorporation into biomaterials for bone repair

article

Gene transfers of vascular endothelial growth factor-A, vascular endothelial growth factor-B, vascular endothelial growth factor-C, and vascular endothelial growth factor-D have no effects on atherosclerosis in hypercholesterolemic low-density lipop

artículo científico publicado en 2005

General principles and approaches of gene therapy

article

Generation of lentivirus vectors using recombinant baculoviruses

artículo científico publicado en 2008

Genes involved in atherosclerosis

artículo científico publicado en 2002

Genetic alterations in the peritumoral stromal cells of malignant and borderline epithelial ovarian tumors as indicated by allelic imbalance on chromosome 3p.

artículo científico publicado en 2004

Genetics, genomics and proteomics in atherosclerosis research

artículo científico publicado en 2005

Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial Infarction

artículo científico publicado en 2017

Glioma cell density in a rat gene therapy model gauged by water relaxation rate along a fictitious magnetic field

artículo científico publicado en 2011

Global DNA methylation analysis of human atherosclerotic plaques reveals extensive genomic hypomethylation and reactivation at imprinted locus 14q32 involving induction of a miRNA cluster

artículo científico publicado en 2014

Glybera's second act: the curtain rises on the high cost of therapy

artículo científico publicado en 2015

Granulocyte transmigration through the endothelium is regulated by the oxidase activity of vascular adhesion protein-1 (VAP-1).

artículo científico publicado en 2004

Growth Factor Therapy and Autologous Lymph Node Transfer in Lymphedema

Growth factor therapy and lymph node graft for lymphedema

artículo científico publicado en 2015

Growth factor-induced therapeutic angiogenesis and arteriogenesis in the heart--gene therapy

artículo científico publicado en 2005

HIF-1 induction attenuates Nrf2-dependent IL-8 expression in human endothelial cells

artículo científico publicado en 2009

HIF-1α and HIF-2α induce angiogenesis and improve muscle energy recovery

artículo científico publicado en 2014

HIF-VEGF-VEGFR-2, TNF-alpha and IGF pathways are upregulated in critical human skeletal muscle ischemia as studied with DNA array

artículo científico publicado en 2004

HSV-tk gene therapy for human renal cell carcinoma in nude mice

artículo científico publicado en 2001

Heme oxygenase 1 is induced by miR-155 via reduced BACH1 translation in endothelial cells

artículo científico publicado en 2011

Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions

artículo científico publicado en 2000

High Plasma Lipid Levels Reduce Efficacy of Adenovirus-Mediated Gene Therapy

artículo científico publicado en 2017

High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer

artículo científico publicado en 2020

High expression of human 15-lipoxygenase induces NF-kappaB-mediated expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and T-cell adhesion on human endothelial cells

artículo científico publicado en 1999

High-resolution ultrasound perfusion imaging of therapeutic angiogenesis

artículo científico publicado en 2008

Highlighting the Field of Cardiovascular Regenerative Medicine

artículo científico publicado en 2018

History of gene therapy

artículo científico

How to avoid complement attack in baculovirus-mediated gene delivery

artículo científico publicado en 2011

Human Vascular Endothelial Growth Factor A Expression Induces the Mouse Model of Neovascular Age-Related Macular Degeneration

article

Human gene therapy and imaging: cardiology

artículo científico publicado en 2005

Hyperbaric oxygen therapy activates hypoxia-inducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice

artículo científico publicado en 2015

Hypoxia and platelet-derived growth factor-BB synergistically upregulate the expression of vascular endothelial growth factor in vascular smooth muscle cells

artículo científico publicado en 1995

Hypoxia induces microRNA miR-210 in vitro and in vivo ephrin-A3 and neuronal pentraxin 1 are potentially regulated by miR-210.

artículo científico publicado en 2008

Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression is an early marker of progressive cardiac remodelling

scientific journal article

Imaging of αvβ3 integrin expression in experimental myocardial ischemia with [68Ga]NODAGA-RGD positron emission tomography

artículo científico publicado en 2017

Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas

artículo científico publicado en 2017

Improved gene transfer efficiency in liver with vesicular stomatitis virus G-protein pseudotyped retrovirus after partial liver resection and thymidine kinase-ganciclovir pre-treatment

artículo científico publicado en 1999

Improved generation of recombinant baculovirus genomes in Escherichia coli

artículo científico publicado en 2003

Improved therapeutic effect on malignant glioma with adenoviral suicide gene therapy combined with temozolomide

artículo científico publicado en 2013

Improvement in adenoviral gene transfer efficiency after preincubation at +37 degrees C in vitro and in vivo

artículo científico publicado en 2002

Improvement in nuclear entry and transgene expression of baculoviruses by disintegration of microtubules in human hepatocytes

artículo científico publicado en 2005

Improving safety of gene therapy

scientific article published on January 2008

In Vivo Low Density Lipoprotein Oxidation Relates to Coronary Reactivity in Young Men

artículo científico publicado en 1997

In vitro targeting of avidin-expressing glioma cells with biotinylated persistent luminescence nanoparticles

artículo científico publicado en 2012

In vivo SPECT/CT imaging of human orthotopic ovarian carcinoma xenografts with 111In-labeled monoclonal antibodies

artículo científico publicado en 2010

In vivo application and tracking of baculovirus

artículo científico publicado en 2010

In vivo inhibition of nuclear factor of activated T-cells leads to atherosclerotic plaque regression in IGF-II/LDLR-/-ApoB100/100 mice

artículo científico publicado en 2018

In vivo phage display screening for tumor vascular targets in glioblastoma identifies a llama nanobody against dynactin-1-p150Glued

artículo científico publicado en 2016

Increased Atherosclerotic Lesion Calcification in a Novel Mouse Model Combining Insulin Resistance, Hyperglycemia, and Hypercholesterolemia

artículo científico publicado en 2007

Increased invasion of malignant gliomas after 15-LO-1 and HSV-tk/ganciclovir combination gene therapy

artículo científico publicado en 2012

Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebo-controlled, double-blinded phase II study

artículo científico publicado en 2002

Induction of 15-lipoxygenase mRNA and protein in early atherosclerotic lesions

artículo científico publicado en 1995

Inhibition of basal and interleukin-1-induced VCAM-1 expression by phospholipid hydroperoxide glutathione peroxidase and 15-lipoxygenase in rabbit aortic smooth muscle cells

artículo científico publicado en 2004

Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.

artículo científico publicado en 2001

Inhibition of urothelial carcinoma through targeted type I interferon-mediated immune activation

artículo científico publicado en 2019

Insights into the molecular pathogenesis of atherosclerosis and therapeutic strategies using gene transfer

artículo científico publicado en 2000

Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies

artículo científico publicado en 1999

Intestinal lymphatic vessels and their role in chylomicron absorption and lipid homeostasis

artículo científico publicado en 2019

Intracardiac injection of a capsid-modified Ad5/35 results in decreased heart toxicity when compared to standard Ad5

artículo científico publicado en 2012

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

artículo científico publicado en 2009

Intramyocardial Gene Therapy Directed to Hibernating Heart Muscle Using a Combination of Electromechanical Mapping and Positron Emission Tomography

artículo científico publicado en 2016

Intravascular adenovirus-mediated VEGF-C gene transfer reduces neointima formation in balloon-denuded rabbit aorta

article

Intravascular adenovirus-mediated lipoprotein-associated phospholipase A2 gene transfer reduces neointima formation in balloon-denuded rabbit aorta

Intravascular ultrasound and magnetic resonance imaging in the assessment of atherosclerotic lesions in rabbit aorta. Correlation to histopathologic findings

artículo científico publicado en 1998

Intravesical rAd-IFNα/Syn3 for Patients With High-Grade, Bacillus Calmette-Guerin-Refractory or Relapsed Non-Muscle-Invasive Bladder Cancer: A Phase II Randomized Study

artículo científico publicado en 2017

Intravitreal adenoviral 15-lipoxygenase-1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes

artículo científico publicado en 2009

Involvement of specific macrophage-lineage cells surrounding arterioles in barrier and scavenger function in brain cortex

artículo científico publicado en 1996

Is oxidized low‐density lipoprotein present in vivo?

artículo científico publicado el 1 de agosto de 1998

Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart

artículo científico publicado en 2016

Isolation of fresh endothelial cells from porcine heart for cardiovascular studies: a new fast protocol suitable for genomic, transcriptomic and cell biology studies

scientific article published on 13 August 2019

KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells

artículo científico publicado en 2008

LDLR-/-ApoB100/100 mice with insulin-like growth factor II overexpression reveal a novel form of retinopathy with photoreceptor atrophy and altered morphology of the retina

artículo científico publicado el 4 de agosto de 2013

Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice.

artículo científico publicado en 2014

Left ventricular dysfunction with reduced functional cardiac reserve in diabetic and non-diabetic LDL-receptor deficient apolipoprotein B100-only mice

artículo científico publicado en 2011

Left ventricular remodeling leads to heart failure in mice with cardiac-specific overexpression of VEGF-B167: echocardiography and magnetic resonance imaging study.

artículo científico publicado en 2017

Lentiviral protein transduction with genome-modifying HIV-1 integrase-I-PpoI fusion proteins: studies on specificity and cytotoxicity

artículo científico publicado en 2014

Leukocyte trafficking-associated vascular adhesion protein 1 is expressed and functionally active in atherosclerotic plaques

artículo científico publicado en 2016

Linked Chromosome 16q13 Chemokines, Macrophage-Derived Chemokine, Fractalkine, and Thymus- and Activation-Regulated Chemokine, Are Expressed in Human Atherosclerotic Lesions

artículo científico publicado en 2001

Lipid accumulation, lipid oxidation, and low plasma levels of acquired antibodies against oxidized lipids associate with degeneration and rupture of the intracranial aneurysm wall

scientific article published on 28 October 2013

Lipoprotein-Associated Phospholipase A 2 , Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions

scientific article published on 01 December 1999

Lipoproteins in normal and atherosclerotic aorta

artículo científico publicado en 1990

Local adventitial anti-angiogenic gene therapy reduces growth of vasa-vasorum and in-stent restenosis in WHHL rabbits

article

Local hypomethylation in atherosclerosis found in rabbit ec-sod gene

artículo científico publicado en 1999

Localization of M2 muscarinic receptor protein in parvalbumin and calretinin containing cells of the adult rat entorhinal cortex using two complementary methods

artículo científico publicado en 2005

Long Non-Coding RNA Modulation of VEGF-A during Hypoxia

artículo científico publicado en 2018

Long-term VEGF-A expression promotes aberrant angiogenesis and fibrosis in skeletal muscle

artículo científico publicado en 2011

Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy

artículo científico publicado en 2004

Longitudinal rotating frame relaxation time measurements in infarcted mouse myocardium in vivo

artículo científico publicado en 2012

Low density lipoprotein undergoes oxidative modification in vivo

artículo científico publicado en 1989

Low efficacy of gene therapy for rat BT4C malignant glioma using intra-tumoural transduction with thymidine kinase retrovirus packaging cell injections and ganciclovir treatment

artículo científico publicado en 1999

Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion

artículo científico publicado en 2017

Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion

artículo científico publicado en 2017

Low spin-lock field T1 relaxation in the rotating frame as a sensitive MR imaging marker for gene therapy treatment response in rat glioma

artículo científico publicado en 2007

Low-grade inflammation and the phenotypic expression of myocardial fibrosis in hypertrophic cardiomyopathy

artículo científico publicado en 2012

Lymph node transfer and perinodal lymphatic growth factor treatment for lymphedema

artículo científico publicado en 2013

Lymphangiogenic gene therapy with minimal blood vascular side effects

artículo científico publicado en 2002

Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation

artículo científico publicado en 2006

Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor

artículo científico publicado en 2002

Lymphatic vasculature is increased in heart valves, ischaemic and inflamed hearts and in cholesterol-rich and calcified atherosclerotic lesions

artículo científico publicado en 2010

Lymphatic vessel insufficiency in hypercholesterolemic mice alters lipoprotein levels and promotes atherogenesis.

artículo científico publicado en 2014

Macrophage colony-stimulating factor mRNA and protein in atherosclerotic lesions of rabbits and humans

artículo científico publicado el 1 de febrero de 1992

Macrophage foam cells from human aortic fatty streaks take up beta-VLDL and acetylated LDL in primary culture

article

Macrophage selective photodynamic therapy by meta-tetra(hydroxyphenyl)chlorin loaded polymeric micelles: A possible treatment for cardiovascular diseases

artículo científico publicado en 2017

Macrophages and Oxidized Low Density Lipoproteins in the Pathogenesis of Atherosclerosis

artículo científico publicado el 1 de enero de 1991

Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions

artículo científico publicado el 15 de noviembre de 1991

Macrophages, endothelial cells, and lipoprotein oxidation in the pathogenesis of atherosclerosis

artículo científico publicado en 1990

Magnetic resonance imaging of viral particle biodistribution in vivo.

artículo científico publicado en 2006

Magnetically Coated Bioabsorbable Stents for Renormalization of Arterial Vessel Walls after Stent Implantation.

artículo científico publicado en 2017

Metabolism of modified LDL and foam cell formation in murine macrophage-like RAW 264 cells

artículo científico publicado en 1999

Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.

artículo científico publicado en 2003

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

scientific article published on 28 September 2020

Modified RNA kick-starts cardiac repair

artículo científico publicado en 2013

Molecular Therapy Special Issue on Gene Editing Technologies and Applications

artículo científico publicado en 2015

Molecular genetics of atherosclerosis

scientific article published on 20 March 2009

Monitoring of lipoprotein oxidation by gas chromatographic analysis of hydroxy fatty acids

artículo científico publicado en 1995

Morphological characterization of baculovirus Autographa californica multiple nucleopolyhedrovirus

scientific article published on 05 December 2009

Mouse ECG findings in aging, with conduction system affecting drugs and in cardiac pathologies: Development and validation of ECG analysis algorithm in mice

artículo científico publicado en 2015

Neuropilin-2 and vascular endothelial growth factor receptor-3 are up-regulated in human vascular malformations

artículo científico publicado en 2012

New Technologies in Cardiovascular Research: Gene Therapy

article

New aspects in vascular gene therapy

artículo científico publicado en 2010

Nitric oxide donor GEA 3162 inhibits endothelial cell-mediated oxidation of low density lipoprotein

artículo científico publicado en 1994

Non-invasive Imaging in Gene Therapy

artículo científico publicado en 2007

Non-specific binding of [18F]FDG to calcifications in atherosclerotic plaques: experimental study of mouse and human arteries

artículo científico publicado en 2006

Nonviral gene delivery methods in cardiovascular diseases

artículo científico publicado en 2005

Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor.

artículo científico publicado en 2011

Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2

article

Novel magnetic resonance imaging contrasts for monitoring response to gene therapy in rat glioma

artículo científico publicado en 2003

Novel targeting of biotinylated compounds to local tissues with avidin-lipoprotein receptor fusion protein.

artículo científico publicado en 2003

Novel vascular endothelial growth factor D variants with increased biological activity

scientific article published on 14 April 2009

Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo

artículo científico publicado en 2007

Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo

artículo científico publicado en 2008

Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid

artículo científico publicado en 2009

Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice

article

Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.

artículo científico publicado en 2008

On the relationship of LDL and VEGFR1: not just a family affair

artículo científico publicado en 2007

Optimization of lentiviral vector production for scale-up in fixed-bed bioreactor

artículo científico publicado en 2017

Optimized in situ PCR method for the detection of gene transfer vector in histological sections

artículo científico publicado en 2001

Optimized self-excising Cre-expression cassette for mammalian cells

artículo científico publicado en 2004

Oral imatinib mesylate (STI571/gleevec) improves the efficacy of local intravascular vascular endothelial growth factor-C gene transfer in reducing neointimal growth in hypercholesterolemic rabbits

artículo científico publicado en 2004

Overexpression of PHGPx inhibits hydroperoxide-induced oxidation, NFkappaB activation and apoptosis and affects oxLDL-mediated proliferation of rabbit aortic smooth muscle cells

artículo científico publicado en 2000

Overexpression of VEGF-A induces neovascularization and increased vascular leakage in rabbit eye after intravitreal adenoviral gene transfer

artículo científico publicado en 2006

Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy

artículo científico publicado en 2008

Oxidation of LDL by rabbit and human 15-lipoxygenase: prevalence of nonenzymatic reactions.

artículo científico publicado en 2001

Oxidative stress-inducible lentiviral vectors for gene therapy.

artículo científico publicado en 2008

Oxidative stress-regulated lentiviral TK/GCV gene therapy for lung cancer treatment

artículo científico publicado en 2012

Oxidized LDL and atherogenesis

artículo científico publicado en 1999

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

scientific article published in Nature

Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis

artículo científico publicado en 2007

PDGF-C and -D and their receptors PDGFR-alpha and PDGFR-beta in atherosclerotic human arteries

artículo científico publicado en 2009

Pathogenesis and treatment of atherosclerosis-related diseases

Pathogenesis of atherosclerosis

artículo científico publicado en 1996

Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.

artículo científico publicado en 2005

Patterns of oxidized epitopes, but not NF-kappa B expression, change during atherogenesis in WHHL rabbits

artículo científico publicado en 2003

Peptide-Retargeted Adenovirus Encoding a Tissue Inhibitor of Metalloproteinase-1 Decreases Restenosis after Intravascular Gene Transfer

article

Percutaneous transcoronary venous access for cellular cardiomyoplasty

artículo científico publicado el 18 de octubre de 2003

Periadventitial angiopoietin-1 gene transfer induces angiogenesis in rabbit carotid arteries

artículo científico publicado en 2005

Periadventitial lacZ gene transfer to pig carotid arteries using a biodegradable collagen collar or a wrap of collagen sheet with adenoviruses and plasmid-liposome complexes

artículo científico publicado en 2000

Peroxisome proliferator-activated receptor-γ coactivator 1 α1 induces a cardiac excitation-contraction coupling phenotype without metabolic remodelling

artículo científico publicado en 2016

Phosphorylation regulates FOXC2-mediated transcription in lymphatic endothelial cells

artículo científico publicado en 2013

Photodynamic Ablation of Lymphatic Vessels and Intralymphatic Cancer Cells Prevents Metastasis

scientific article published on 01 February 2011

Platelet-derived Growth Factor-B Protects Rat Cardiac Allografts From Ischemia-reperfusion Injury

artículo científico publicado en 2015

Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with 18F-GE-180, a Radiotracer for Translocator Protein (TSPO).

artículo científico publicado en 2018

Positron emission tomography tracer [68GA]NODAGA-EXENDIN-4 detects glucagon-like peptide-1 receptor expression in mouse atherosclerotic vascular lesions

Post-intervention vessel remodeling

artículo científico publicado en 2002

Post-transcriptional regulatory element boosts baculovirus-mediated gene expression in vertebrate cells

artículo científico publicado en 2007

Postmenopausal hormone replacement therapy and autoantibodies against oxidized LDL.

artículo científico publicado en 1998

Preclinical Proof-of-Concept, Analytical Development, and Commercial Scale Production of Lentiviral Vector in Adherent Cells

artículo científico publicado en 2019

Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer

artículo científico publicado en 2013

Preoperative angiopoietin-2 serum levels: a marker of malignant potential in ovarian neoplasms and poor prognosis in epithelial ovarian cancer

artículo científico publicado en 2010

Preparation of recombinant baculoviruses with the BVboost system

artículo científico publicado en 2009

Primary and metastatic ovarian cancer: Characterization by 3.0T diffusion-weighted MRI.

artículo científico publicado en 2017

Primary effect of 1α,25(OH)₂D₃ on IL-10 expression in monocytes is short-term down-regulation

artículo científico publicado en 2010

Pro- and anti-angiogenic therapy and atherosclerosis with special emphasis on vascular endothelial growth factors

artículo científico publicado en 2011

Process Development of Adenoviral Vector Production in Fixed Bed Bioreactor: From Bench to Commercial Scale

artículo científico publicado en 2015

Production and purification of lentiviral vectors generated in 293T suspension cells with baculoviral vectors

artículo científico publicado en 2011

Production of HIV-1 integrase fusion protein-carrying lentiviral vectors for gene therapy and protein transduction

artículo científico publicado en 2010

Production of functional recombinant tyrosine hydroxylase by the BPV-1 expression plasmids in the cell cultures

artículo científico publicado en 2003

Profiling of Primary and Mature miRNA Expression in Atherosclerosis-Associated Cell Types

artículo científico publicado en 2021

Progress and prospects: gene therapy clinical trials (part 1).

artículo científico publicado en 2007

Progress and prospects: hurdles to cardiovascular gene therapy clinical trials

artículo científico publicado en 2011

Promoter polymorphisms -359T/C and -303A/G of the catalytic subunit p110beta gene of human phosphatidylinositol 3-kinase are not associated with insulin secretion or insulin sensitivity in finnish subjects

artículo científico publicado en 2003

Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success

artículo científico

Prospect and progress of gene therapy in treating atherosclerosis

artículo científico

Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia

artículo científico publicado en 2008

Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

artículo científico publicado en 2018

Quantification of porcine myocardial perfusion with modified dual bolus MRI - a prospective study with a PET reference

artículo científico publicado en 2019

Quantitative 1H nuclear magnetic resonance diffusion spectroscopy of BT4C rat glioma during thymidine kinase-mediated gene therapy in vivo: identification of apoptotic response

artículo científico publicado en 1998

Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL.

artículo científico publicado en 1994

Rabbit atherosclerotic lesions express scavenger receptor AIII mRNA, a naturally occurring splice variant that encodes a non-functional, dominant negative form of the macrophage scavenger receptor

artículo científico publicado en 2001

Rabbit extracellular superoxide dismutase: expression and effect on LDL oxidation

artículo científico publicado en 2000

Recent Advancements in Cardiovascular Gene Therapy and Vascular Biology

artículo científico

Recent advances in novel therapies for lipid disorders

scientific article published on 01 October 2019

Receptor-mediated binding and degradation of subfractions of human plasma low-density lipoprotein by cultured fibroblasts

artículo científico publicado en 1989

Regulation of VEGF-A Expression in Endothelial Cells by Transcriptional Gene Activation or Transcriptional Gene Silencing: Analysis of Genome Wide Transcriptional Response

article

Regulation of endothelial lipase and systemic HDL cholesterol levels by SREBPs and VEGF-A.

artículo científico publicado en 2012

Release of replication-deficient retroviruses from a packaging cell line: interaction with glioma tumor spheroids in vitro

artículo científico publicado en 1997

Relevance of an academic GMP Pan-European vector infra-structure (PEVI).

artículo científico

Reply to "heparan sulfate in baculovirus binding and entry of Mammalian cells".

artículo científico publicado en 2014

Reply to Kerbel et al.: EPCs are again claimed to be essential in yet other models despite the irreproducibility of the original experiments introducing them

artículo científico publicado en 2008

Requirements for baculoviruses for clinical gene therapy applications

scientific article published on July 2011

Research update for articles published in EJCI in 2011

Resectable VX-2 rabbit brain tumor model for development of intraoperative local administration of drugs

artículo científico publicado en 2011

Residual adverse changes in arterial endothelial function and LDL oxidation after a mild systemic inflammation induced by influenza vaccination

artículo científico publicado en 2007

Respiratory infection recurrence and passive smoking in early atherosclerosis in children and adolescents with type 1 diabetes

artículo científico publicado en 2008

Retrovirus-mediated, stable scavenger-receptor gene transfer leads to functional endocytotic receptor expression, foam cell formation, and increased susceptibility to apoptosis in rabbit aortic smooth muscle cells

artículo científico publicado en 2000

Review focus on epigenetics and the histone code in vascular biology

artículo científico publicado en 2011

Rhizavidin from Rhizobium etli: the first natural dimer in the avidin protein family

artículo científico publicado en 2007

Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B)

artículo científico publicado en 2013

SPECT/CT imaging of baculovirus biodistribution in rat.

artículo científico publicado en 2007

SUR1-E1506K mutation impairs glucose tolerance and promotes vulnerable atherosclerotic plaque phenotype in hypercholesterolemic mice

artículo científico publicado en 2021

Safety and Feasibility of Catheter-Based Local Intracoronary Vascular Endothelial Growth Factor Gene Transfer in the Prevention of Postangioplasty and In-Stent Restenosis and in the Treatment of Chronic Myocardial Ischemia

artículo científico publicado el 12 de mayo de 2003

Safety profile of plasmid/liposomes and virus vectors in clinical gene therapy

artículo científico publicado en 2006

Screening of complement inhibitors: shielded baculoviruses increase the safety and efficacy of gene delivery

artículo científico publicado en 2010

Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease

artículo científico publicado en 1995

Serial Optical Coherence Tomography at Baseline, 7 Days, and 1, 3, 6 and 12 Months After Bioresorbable Scaffold Implantation in a Growing Porcine Model

scientific article published on 31 January 2019

Serum angiopoietin-2 and soluble VEGFR-2 levels predict malignancy of ovarian neoplasm and poor prognosis in epithelial ovarian cancer

artículo científico publicado en 2014

Severe coronary artery stenoses and reduced coronary flow velocity reserve in atherosclerotic mouse model

article

Short and long-term effects of hVEGF-A(165) in Cre-activated transgenic mice

artículo científico publicado en 2006

Silencing of either SR-A or CD36 reduces atherosclerosis in hyperlipidaemic mice and reveals reciprocal upregulation of these receptors

artículo científico publicado en 2010

Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2.

artículo científico publicado en 2008

Sleeping Beauty Transposon Vectors in Liver-directed Gene Delivery of LDLR and VLDLR for Gene Therapy of Familial Hypercholesterolemia

artículo científico publicado en 2015

Sleeping Beauty-baculovirus hybrid vectors for long-term gene expression in the eye.

artículo científico publicado en 2014

Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle via reduced eNOS activity

artículo científico publicado en 2015

Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions

Smooth Muscle Cell Foam Cell Formation, Apolipoproteins, and ABCA1 in Intracranial Aneurysms: Implications for Lipid Accumulation as a Promoter of Aneurysm Wall Rupture

artículo científico publicado en 2016

Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling

artículo científico publicado en 2017

Soluble vascular endothelial growth factor receptor-1 improves therapeutic efficacy of suicide gene therapy in an angiogenesis-independent manner

artículo científico publicado en 2014

Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain

artículo científico publicado en 2018

Specific inhibition of SRC kinase impairs malignant glioma growth in vitro and in vivo

artículo científico publicado en 2012

Stabilisation of atherosclerotic plaques

artículo científico publicado en 2011

Stabilization of HIF-1alpha is critical to improve wound healing in diabetic mice

scholarly article

Stabilization of atherosclerotic plaques: an update

artículo científico publicado en 2013

Stabilized HIF-1alpha is superior to VEGF for angiogenesis in skeletal muscle via adeno-associated virus gene transfer

artículo científico publicado en 2005

Stable RNA interference: comparison of U6 and H1 promoters in endothelial cells and in mouse brain.

artículo científico publicado en 2006

Stimulation of functional vessel growth by gene therapy

artículo científico publicado en 2010

Structural determinants of vascular endothelial growth factor-D receptor binding and specificity

artículo científico publicado en 2011

Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells

artículo científico publicado en 2010

Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.

artículo científico publicado en 2002

TAFFEL: Independent Enrichment Analysis of gene sets

artículo científico publicado en 2011

Targeted delivery via avidin fusion protein: intracellular fate of biotinylated doxorubicin derivative and cellular uptake kinetics and biodistribution of biotinylated liposomes

artículo científico publicado en 2012

Targeted magnetic resonance imaging of Scavidin-receptor in human umbilical vein endothelial cells in vitro

artículo científico publicado en 2006

Targeting and purification of metabolically biotinylated baculovirus

artículo científico publicado en 2008

Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts.

artículo científico publicado en 2010

Targeting of biotinylated compounds to its target tissue using a low-density lipoprotein receptor-avidin fusion protein

artículo científico publicado en 2003

Temporal Dynamics of Gene Expression During Endothelial Cell Differentiation From Human iPS Cells: A Comparison Study of Signalling Factors and Small Molecules

artículo científico publicado en 2018

The Need for Increased Clarity and Transparency in the Regulatory Pathway for Gene Medicines in the European Union

artículo científico publicado el 1 de marzo de 2012

The Pharmacology of Gene Therapy

artículo científico publicado en 2017

The Strengths and Weaknesses of VEGF Adenovirus-Driven Angiogenesis

The Syngeneic BT4C Rat Malignant Glioma is a Valuable Model to study Myelomonocytic cells in Tumors

The absence of macrophage Nrf2 promotes early atherogenesis

artículo científico publicado en 2013

The administration of an adenoviral thymidine kinase suicide gene to the uterine artery of rabbits does not affect fertility: a safety study of pregnant and nonpregnant rabbits and their offspring

artículo científico publicado en 2008

The atherosclerotic lesion: a dynamic landscape

artículo científico publicado en 1998

The bottleneck stent model for chronic myocardial ischemia and heart failure in pigs

artículo científico publicado en 2013

The combination of HSV-tk and endostatin gene therapy eradicates orthotopic human renal cell carcinomas in nude mice

artículo científico publicado en 2002

The development of interferon-based gene therapy for BCG unresponsive bladder cancer: from bench to bedside

artículo científico publicado en 2018

The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: rationale and design of the BAMI trial.

artículo científico publicado en 2017

The effect of proteoglycans, collagen and lysyl oxidase on the metabolism of low density lipoprotein by macrophages

artículo científico publicado en 1986

The effect of subcellular localization on the efficiency of EGFR-targeted VHH photosensitizer conjugates

artículo científico publicado en 2017

The effects of VEGF-A on atherosclerosis, lipoprotein profile, and lipoprotein lipase in hyperlipidaemic mouse models

artículo científico publicado en 2013

The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice

artículo científico publicado en 2009

The follow-up of progressive hypertrophic cardiomyopathy using magnetic resonance rotating frame relaxation times

artículo científico publicado en 2017

The genetic and metabolic determinants of cardiovascular complications in type 2 diabetes: recent insights from animal models and clinical investigations

artículo científico publicado en 2013

The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features

scholarly article by Tiina Nieminen published in January 2014

The molecular therapy family: past, present, and future

artículo científico publicado en 2015

The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis

artículo científico publicado en 2008

The use of low-molecular-weight PEIs as gene carriers in the monkey fibroblastoma and rabbit smooth muscle cell cultures

artículo científico publicado en 2002

Therapeutic angiogenesis with placental growth factor improves exercise tolerance of ischaemic rabbit hindlimbs

artículo científico publicado en 2008

Therapeutic delivery using gene-delivery methods

artículo científico publicado en 2011

Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation.

artículo científico publicado en 2007

Therapeutic effects of rosuvastatin in hypercholesterolemic prediabetic mice in the absence of low density lipoprotein receptor

scientific article published on 30 November 2018

Therapeutic gene targeting approaches for the treatment of dyslipidemias and atherosclerosis

artículo científico publicado en 2013

Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses

artículo científico publicado en 2000

Tie1 controls angiopoietin function in vascular remodeling and inflammation

artículo científico publicado en 2016

Tissue inhibitor of metalloproteinase 1 adenoviral gene therapy alone is equally effective in reducing restenosis as combination gene therapy in a rabbit restenosis model

artículo científico publicado en 2005

Tomato thymidine kinase-based suicide gene therapy for malignant glioma--an alternative for Herpes Simplex virus-1 thymidine kinase

artículo científico publicado en 2015

Transcriptional Profiling of Hypoxia-Regulated Non-coding RNAs in Human Primary Endothelial Cells

artículo científico publicado en 2018

Transduction of vertebrate cells with recombinant baculovirus

artículo científico publicado en 2009

Transduction patterns and efficiencies in rabbit uterine tissues after intraluminal uterine adenovirus administration vary with the reproductive cycle

artículo científico publicado en 2007

Transfection of oocytes and other types of ovarian cells in rabbits after direct injection into uterine arteries of adenoviruses and plasmid/liposomes.

artículo científico publicado en 2003

Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein

artículo científico publicado en 1995

Transplantation of adipose tissue mesenchymal cells conjugated with VEGF-releasing microcarriers promotes repair in murine myocardial infarction.

artículo científico publicado en 2015

Truncated vesicular stomatitis virus G protein improves baculovirus transduction efficiency in vitro and in vivo

artículo científico publicado en 2006

Tumor suppressor and growth regulatory genes are overexpressed in severe early-onset preeclampsia--an array study on case-specific human preeclamptic placental tissue

artículo científico publicado en 2005

Two Decades of Molecular Therapy: The Journey Continues

scholarly article by Robert M Frederickson & Seppo Ylä-Herttuala published 2 January 2019 in Molecular Therapy

Type 2 diabetes enhances arterial uptake of choline in atherosclerotic mice: an imaging study with positron emission tomography tracer ¹⁸F-fluoromethylcholine

artículo científico publicado en 2016

Type I interferon response against viral and non-viral gene transfer in human tumor and primary cell lines

artículo científico publicado en 2007

Ultrasound imaging with bolus delivered contrast agent for the detection of angiogenesis and blood flow irregularities

artículo científico publicado en 2014

Umbilical cord blood-derived progenitor cells enhance muscle regeneration in mouse hindlimb ischemia model

artículo científico publicado en 2007

Upregulated signaling pathways in ruptured human saccular intracranial aneurysm wall: an emerging regulative role of Toll-like receptor signaling and nuclear factor-κB, hypoxia-inducible factor-1A, and ETS transcription factors

artículo científico publicado en 2011

Uptake of 11C-choline in mouse atherosclerotic plaques

artículo científico publicado en 2010

Uptake of 68gallium in atherosclerotic plaques in LDLR-/-ApoB100/100 mice

artículo científico publicado en 2011

Uptake of inflammatory cell marker [11C]PK11195 into mouse atherosclerotic plaques

artículo científico publicado en 2008

VEGF Gene Transfer Reduces Intimal Thickening via Increased Production of Nitric Oxide in Carotid Arteries

article

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

artículo científico publicado en 2010

VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis

artículo científico publicado en 2008

VEGF-A, VEGF-D and VEGF-D(DeltaNDeltaC) induced intimal hyperplasia in carotid arteries

artículo científico publicado en 2005

VEGF-A, VEGF-D, VEGF receptor-1, VEGF receptor-2, NF-κB, and RAGE in atherosclerotic lesions of diabetic Watanabe heritable hyperlipidemic rabbits

artículo científico publicado en 2006

VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

artículo científico publicado en 2009

VEGF-C and VEGF-C156S in the pro-lymphangiogenic growth factor therapy of lymphedema: a large animal study

artículo científico publicado en 2015

VEGF-C induced angiogenesis preferentially occurs at a distance from lymphangiogenesis.

artículo científico publicado en 2007

VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses

artículo científico publicado en 2003

VEGF-DdeltaNdeltaC mediated angiogenesis in skeletal muscles of diabetic WHHL rabbits

artículo científico publicado en 2010

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.

artículo científico publicado en 2011

Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart

artículo científico publicado en 2017

Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels

artículo científico publicado en 2005

Vascular endothelial growth factor (VEGF) gene transfer enhances surgical revascularization of necrotic bone

article

Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects

artículo científico publicado en 2011

Vascular endothelial growth factor B controls endothelial fatty acid uptake.

artículo científico publicado en 2010

Vascular endothelial growth factor C-induced collateral formation in a model of myocardial ischemia

artículo científico publicado en 2005

Vascular endothelial growth factor enhances cardiac allograft arteriosclerosis.

artículo científico publicado en 2002

Vascular endothelial growth factor-A and platelet-derived growth factor-B combination gene therapy prolongs angiogenic effects via recruitment of interstitial mononuclear cells and paracrine effects rather than improved pericyte coverage of angiogen

artículo científico publicado en 2008

Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment

artículo científico publicado en 2006

Vascular endothelial growth factor-B acts as a coronary growth factor in transgenic rats without inducing angiogenesis, vascular leak, or inflammation

artículo científico publicado en 2010

Vascular endothelial growth factor-B gene transfer prevents angiotensin II-induced diastolic dysfunction via proliferation and capillary dilatation in rats

artículo científico publicado en 2010

Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1- and neuropilin receptor-1-dependent mechanisms

artículo científico publicado en 2009

Vascular endothelial growth factor-C accelerates diabetic wound healing

artículo científico publicado en 2006

Vascular endothelial growth factor-C gene therapy restores lymphatic flow across incision wounds.

artículo científico publicado en 2004

Vascular endothelial growth factor-D expression in human atherosclerotic lesions

scientific article published on 01 October 2003

Vascular endothelial growth factor-D transgenic mice show enhanced blood capillary density, improved postischemic muscle regeneration, and increased susceptibility to tumor formation

artículo científico publicado en 2008

Vascular endothelial growth factor-angiopoietin chimera with improved properties for therapeutic angiogenesis

artículo científico publicado en 2013

Vascular endothelial growth factors in retinal and choroidal neovascular diseases

artículo científico publicado en 2011

Vascular endothelial growth factors: biology and current status of clinical applications in cardiovascular medicine

artículo científico publicado en 2007

Vascular gene transfer for the treatment of restenosis and atherosclerosis

artículo científico publicado en 1998

Vascular oligonucleotide transfer facilitated by a polymer-coated stent

artículo científico publicado en 2005

Water diffusion in a rat glioma during ganciclovir-thymidine kinase gene therapy-induced programmed cell death in vivo: correlation with cell density.

artículo científico publicado en 2004

Water spin dynamics during apoptotic cell death in glioma gene therapy probed by T1rho and T2rho

artículo científico publicado en 2008

What have we learnt about microarray analyses of atherogenesis?

artículo científico publicado en 2005

Writing the Next Chapter for the Molecular Therapy Family of Journals

artículo científico publicado en 2016

[18F]fluorodeoxyglucose uptake in atherosclerotic plaques is associated with reduced coronary flow reserve in mice

artículo científico publicado en 2014

[How to make scar tissue in cardiac muscle beat?]

artículo científico publicado en 2005

[Human gene therapy]

artículo científico publicado en 1996

lacZ-neoR transfected glioma cells in syngeneic rats: growth pattern and characterization of the host immune response against cells transplanted inside and outside the CNS.

artículo científico publicado en 2000

rDNA-directed integration by an HIV-1 integrase--I-PpoI fusion protein

artículo científico publicado en 2012