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A Thermodynamic Funnel Drives Bacterial Lipopolysaccharide Transfer in the TLR4 Pathway

scientific article published on 17 May 2018

Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub.

artículo científico publicado en 2018

De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits

artículo científico publicado en 2020

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism.

artículo científico publicado en 2018

Interaction of the antimicrobial peptide polymyxin B1 with both membranes of E. coli: a molecular dynamics study

artículo científico publicado en 2015

Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides

artículo científico publicado en 2018

Structural basis for endotoxin neutralization and anti-inflammatory activity of thrombin-derived C-terminal peptides

Structure and Dynamics of Cinnamycin-Lipid Complexes: Mechanisms of Selectivity for Phosphatidylethanolamine Lipids

scientific article published on 28 October 2019

The Structural Basis for Lipid a Recognition in the CD14 Innate Immune Co-Receptor

The membranes of Gram-negative bacteria: progress in molecular modelling and simulation

artículo científico

The role of protein-protein interactions in Toll-like receptor function.

artículo científico

Understanding and modelling the interactions of peptides with membranes: from partitioning to self-assembly

scientific article published on 29 January 2020