Lista de obras -

An Amino Acid Position at Crossroads of Evolution of Protein Function: ANTIBIOTIC SENSOR DOMAIN OF BlaR1 PROTEIN FROM STAPHYLOCOCCUS AUREUS VERSUS CLASS D -LACTAMASES

artículo científico publicado en 2012

An integrated approach for discovery of highly potent and selective Mnk inhibitors: Screening, synthesis and SAR analysis

artículo científico publicado en 2015

Anharmonic effects in ammonium nitrate and hydroxylammonium nitrate clusters

scientific article published on 01 May 2007

CDK5 in oncology: recent advances and future prospects.

artículo científico publicado en 2017

Computational approach for ranking mutant enzymes according to catalytic reaction rates

artículo científico publicado en 2009

Cyclin-Dependent Kinase 8: A New Hope in Targeted Cancer Therapy?

artículo científico publicado en 2017

Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling

artículo científico publicado en 2013

Discovery and Pharmacological Characterisation of a Novel Series of Highly Selective Inhibitors of Cyclin-Dependent Kinases 4 and 6 as Anticancer Agents.

artículo científico publicado en 2017

Discovery of 4-(dihydropyridinon-3-yl)amino-5-methylthieno[2,3-d]pyrimidine derivatives as potent Mnk inhibitors: synthesis, structure-activity relationship analysis and biological evaluation.

artículo científico publicado en 2015

Discovery of 5-(2-(phenylamino)pyrimidin-4-yl)thiazol-2(3H)-one derivatives as potent Mnk2 inhibitors: synthesis, SAR analysis and biological evaluation

artículo científico publicado en 2014

Discovery of CDK5 Inhibitors through Structure-Guided Approach

scientific article published on 20 March 2019

Discovery of a new class of non-β-lactam inhibitors of penicillin-binding proteins with Gram-positive antibacterial activity.

artículo científico publicado en 2014

Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one

artículo científico publicado en 2015

Dynamical insights of Mnk2 kinase activation by phosphorylation to facilitate inhibitor discovery

artículo científico publicado en 2015

Glycosylation at Asn211 regulates the activation state of the discoidin domain receptor 1 (DDR1).

artículo científico publicado en 2014

High-Resolution Crystal Structure of MltE, an Outer Membrane-Anchored Endolytic Peptidoglycan Lytic Transglycosylase from Escherichia coli

artículo científico publicado en 2011

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

artículo científico publicado en 2013

Implementation of umbrella integration within the framework of the empirical valence bond approach

artículo científico publicado en 2008

In Search of Novel CDK8 Inhibitors by Virtual Screening

artículo científico publicado en 2017

Lysine Nζ-Decarboxylation Switch and Activation of the β-Lactam Sensor Domain of BlaR1 Protein of Methicillin-resistant Staphylococcus aureus ⬇️

artículo científico publicado el 20 de julio de 2011

MAP kinase-interacting kinases--emerging targets against cancer

artículo científico publicado en 2014

Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram‐negative bacterial outer membrane ⬇️

artículo científico publicado el 30 de septiembre de 2011

Mechanism of the Escherichia coli MltE lytic transglycosylase, the cell-wall-penetrating enzyme for Type VI secretion system assembly.

artículo científico publicado en 2018

Protonation states of active-site lysines of penicillin-binding protein 6 from Escherichia coli and the mechanistic implications.

artículo científico publicado en 2014

Shedding of Discoidin Domain Receptor 1 by Membrane-type Matrix Metalloproteinases ⬇️

artículo científico publicado el 21 de marzo de 2013

Structural Analysis of the Role of Pseudomonas aeruginosa Penicillin-Binding Protein 5 in -Lactam Resistance

artículo científico publicado en 2013

Structural Basis for Carbapenemase Activity of the OXA-23 β-Lactamase from Acinetobacter baumannii

artículo científico publicado en 2013

Structural Basis for Progression toward the Carbapenemase Activity in the GES Family of β-Lactamases ⬇️

artículo científico publicado el 16 de noviembre de 2012

Structure-Activity Relationship for Thiirane-Based Gelatinase Inhibitors

artículo científico publicado en 2012

Synthesis and biological evaluation of heteroaryl styryl sulfone derivatives as anticancer agents.

artículo científico publicado en 2016

Synthesis and evaluation of 1,2,4-triazolo[1,5-a]pyrimidines as antibacterial agents against Enterococcus faecium

artículo científico publicado en 2015

Targeting CDK6 in cancer: State of the art and new insights

artículo científico publicado en 2015

Targeting CDK9: a promising therapeutic opportunity in prostate cancer

artículo científico publicado en 2016

Targeting Pim kinases for cancer treatment: opportunities and challenges

artículo científico publicado en 2015

Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials

artículo científico publicado en 2015

Lista de obras de

An Amino Acid Position at Crossroads of Evolution of Protein Function: ANTIBIOTIC SENSOR DOMAIN OF BlaR1 PROTEIN FROM STAPHYLOCOCCUS AUREUS VERSUS CLASS D -LACTAMASES

An integrated approach for discovery of highly potent and selective Mnk inhibitors: Screening, synthesis and SAR analysis

Anharmonic effects in ammonium nitrate and hydroxylammonium nitrate clusters

CDK5 in oncology: recent advances and future prospects.

Computational approach for ranking mutant enzymes according to catalytic reaction rates

Cyclin-Dependent Kinase 8: A New Hope in Targeted Cancer Therapy?

Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling

Discovery and Pharmacological Characterisation of a Novel Series of Highly Selective Inhibitors of Cyclin-Dependent Kinases 4 and 6 as Anticancer Agents.

Discovery of 4-(dihydropyridinon-3-yl)amino-5-methylthieno[2,3-d]pyrimidine derivatives as potent Mnk inhibitors: synthesis, structure-activity relationship analysis and biological evaluation.

Discovery of 5-(2-(phenylamino)pyrimidin-4-yl)thiazol-2(3H)-one derivatives as potent Mnk2 inhibitors: synthesis, SAR analysis and biological evaluation

Discovery of CDK5 Inhibitors through Structure-Guided Approach

Discovery of a new class of non-β-lactam inhibitors of penicillin-binding proteins with Gram-positive antibacterial activity.

Discovery of antibiotic (E)-3-(3-carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one

Dynamical insights of Mnk2 kinase activation by phosphorylation to facilitate inhibitor discovery

Glycosylation at Asn211 regulates the activation state of the discoidin domain receptor 1 (DDR1).

High-Resolution Crystal Structure of MltE, an Outer Membrane-Anchored Endolytic Peptidoglycan Lytic Transglycosylase from Escherichia coli

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

Implementation of umbrella integration within the framework of the empirical valence bond approach

In Search of Novel CDK8 Inhibitors by Virtual Screening

Lysine Nζ-Decarboxylation Switch and Activation of the β-Lactam Sensor Domain of BlaR1 Protein of Methicillin-resistant Staphylococcus aureus ⬇️

MAP kinase-interacting kinases--emerging targets against cancer

Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram‐negative bacterial outer membrane ⬇️

Mechanism of the Escherichia coli MltE lytic transglycosylase, the cell-wall-penetrating enzyme for Type VI secretion system assembly.

Protonation states of active-site lysines of penicillin-binding protein 6 from Escherichia coli and the mechanistic implications.

Shedding of Discoidin Domain Receptor 1 by Membrane-type Matrix Metalloproteinases ⬇️

Structural Analysis of the Role of Pseudomonas aeruginosa Penicillin-Binding Protein 5 in -Lactam Resistance

Structural Basis for Carbapenemase Activity of the OXA-23 β-Lactamase from Acinetobacter baumannii

Structural Basis for Progression toward the Carbapenemase Activity in the GES Family of β-Lactamases ⬇️

Structure-Activity Relationship for Thiirane-Based Gelatinase Inhibitors

Synthesis and biological evaluation of heteroaryl styryl sulfone derivatives as anticancer agents.

Synthesis and evaluation of 1,2,4-triazolo[1,5-a]pyrimidines as antibacterial agents against Enterococcus faecium

Targeting CDK6 in cancer: State of the art and new insights

Targeting CDK9: a promising therapeutic opportunity in prostate cancer

Targeting Pim kinases for cancer treatment: opportunities and challenges

Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials