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A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions

scientific article published on 10 January 2020

A mutation in the Mod subunit of EcoP15I restriction enzyme converts the DNA methyltransferase to a site-specific endonuclease.

artículo científico publicado en 2006

A novel 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNFα by abrogating NF-κB activation cascade

artículo científico publicado en 2016

Annexin-A1 controls an ERK-RhoA-NFκB activation loop in breast cancer cells.

artículo científico publicado en 2015

Annexin-A1 regulates TLR-mediated IFN-β production through an interaction with TANK-binding kinase 1.

artículo científico publicado en 2013

Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells.

artículo científico publicado en 2014

ArfGAP Domain-Containing Protein 2 (ADAP2) Integrates Upstream and Downstream Modules of RIG-I Signaling and Facilitates Type I Interferon Production

artículo científico publicado en 2016

Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response

artículo científico publicado en 2015

Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells.

artículo científico publicado en 2010

Collaboration between Distinct Rab Small GTPase Trafficking Circuits Mediates Bacterial Clearance from the Bladder Epithelium

artículo científico publicado en 2017

Dengue virus activates cGAS through the release of mitochondrial DNA

artículo científico publicado en 2017

E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.

artículo científico publicado en 2017

Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma

artículo científico publicado en 2013

Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.

artículo científico publicado en 2017

Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival.

artículo científico publicado en 2006

Global functional profiling of human ubiquitome identifies E3 ubiquitin ligase DCST1 as a novel negative regulator of Type-I interferon signaling

artículo científico publicado en 2016

Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response

artículo científico publicado en 2014

Identification and mutational analysis of Mg2+ binding site in EcoP15I DNA methyltransferase: involvement in target base eversion

artículo científico publicado en 2003

Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model

artículo científico publicado en 2011

Integrity of GH-loop of foot-and-mouth disease virus during virus inactivation: detection by epitope specific antibodies

artículo científico publicado en 2002

Intracellular Uropathogenic E. coli Exploits Host Rab35 for Iron Acquisition and Survival within Urinary Bladder Cells

artículo científico publicado en 2015

MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection

artículo científico publicado en 2019

Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

artículo científico publicado en 2011

Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance

artículo científico publicado en 2007

Scrub typhus with sepsis and acute respiratory distress syndrome

artículo científico publicado en 2013

The Nod1, Nod2, and Rip2 axis contributes to host immune defense against intracellular Acinetobacter baumannii infection

artículo científico publicado en 2013

Tumor suppressor SMAR1 represses IkappaBalpha expression and inhibits p65 transactivation through matrix attachment regions

artículo científico publicado en 2008