Lista de obras -

2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture.

artículo científico publicado en 2017

Adenosine Dioxolane Nucleoside Phosphoramidates as Antiviral Agents for Human Immunodeficiency and Hepatitis B Viruses

artículo científico publicado en 2013

Biochemical Characterization of the Active Anti-Hepatitis C Virus Metabolites of 2,6-Diaminopurine Ribonucleoside Prodrug Compared to Sofosbuvir and BMS-986094.

artículo científico publicado en 2016

Characterization of β-d-N4-Hydroxycytidine as a Novel Inhibitor of Chikungunya Virus

artículo científico publicado en 2017

Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors

artículo científico publicado en 2015

Discovery of a Series of 2'-α-Fluoro,2'-β-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus

artículo científico publicado en 2019

Efficacy and safety of 3-week response-guided triple direct-acting antiviral therapy for chronic hepatitis C infection: a phase 2, open-label, proof-of-concept study

artículo científico publicado en 2016

Enhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decay kinetics

artículo científico publicado en 2014

Impact of protease inhibitors on intracellular concentration of tenofovir-diphosphate among HIV-1 infected patients

artículo científico publicado en 2015

Pharmacokinetics and Placental Transfer of Elvitegravir, Dolutegravir, and Other Antiretrovirals during Pregnancy

artículo científico publicado en 2017

Randomized, double-blind, multicenter safety and efficacy study of rifalazil compared with azithromycin for treatment of uncomplicated genital Chlamydia trachomatis infection in women

artículo científico publicado en 2014

Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine

artículo científico publicado en 2020

Substrates and Inhibitors of SAMHD1.

artículo científico publicado en 2017

Synthesis and Evaluation of 2,6-Modified Purine 2'-C-Methyl Ribonucleosides as Inhibitors of HCV Replication

artículo científico publicado en 2015

Synthesis and evaluation of novel potent HCV NS5A inhibitors

artículo científico publicado en 2012

Telbivudine exerts no antiviral activity against HIV-1 in vitro and in humans.

artículo científico publicado en 2011

Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex

The Janus kinase inhibitor ruxolitinib reduces HIV replication in human macrophages and ameliorates HIV encephalitis in a murine model

artículo científico publicado en 2016

dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages.

artículo científico publicado en 2014

β-D-2'-C-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5'-Triphosphate Forms

artículo científico publicado en 2015

Lista de obras de

2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture.

Adenosine Dioxolane Nucleoside Phosphoramidates as Antiviral Agents for Human Immunodeficiency and Hepatitis B Viruses

Biochemical Characterization of the Active Anti-Hepatitis C Virus Metabolites of 2,6-Diaminopurine Ribonucleoside Prodrug Compared to Sofosbuvir and BMS-986094.

Characterization of β-d-N4-Hydroxycytidine as a Novel Inhibitor of Chikungunya Virus

Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors

Discovery of a Series of 2'-α-Fluoro,2'-β-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus

Efficacy and safety of 3-week response-guided triple direct-acting antiviral therapy for chronic hepatitis C infection: a phase 2, open-label, proof-of-concept study

Enhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decay kinetics

Impact of protease inhibitors on intracellular concentration of tenofovir-diphosphate among HIV-1 infected patients

Pharmacokinetics and Placental Transfer of Elvitegravir, Dolutegravir, and Other Antiretrovirals during Pregnancy

Randomized, double-blind, multicenter safety and efficacy study of rifalazil compared with azithromycin for treatment of uncomplicated genital Chlamydia trachomatis infection in women

Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine

Substrates and Inhibitors of SAMHD1.

Synthesis and Evaluation of 2,6-Modified Purine 2'-C-Methyl Ribonucleosides as Inhibitors of HCV Replication

Synthesis and evaluation of novel potent HCV NS5A inhibitors

Telbivudine exerts no antiviral activity against HIV-1 in vitro and in humans.

Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex

The Janus kinase inhibitor ruxolitinib reduces HIV replication in human macrophages and ameliorates HIV encephalitis in a murine model

dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages.

β-D-2'-C-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5'-Triphosphate Forms