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2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture.

artículo científico publicado en 2017

Acute acalculous cholecystitis during Zika virus infection in an immunocompromised patient

artículo científico publicado en 2017

Adenosine Dioxolane Nucleoside Phosphoramidates as Antiviral Agents for Human Immunodeficiency and Hepatitis B Viruses

artículo científico publicado en 2013

Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides

scientific article published on 13 July 2009

Approaches to hepatitis C treatment and cure using NS5A inhibitors

scientific article published on 05 March 2014

Cellular pharmacology and potency of HIV-1 nucleoside analogs in primary human macrophages

artículo científico publicado en 2012

Characterization of dengue virus 2 growth in megakaryocyte-erythrocyte progenitor cells

artículo científico publicado en 2016

Combinations of 2'-C-methylcytidine analogues with interferon-alpha2b and triple combination with ribavirin in the hepatitis C virus replicon system

artículo científico publicado en 2008

Efficacy and safety of 3-week response-guided triple direct-acting antiviral therapy for chronic hepatitis C infection: a phase 2, open-label, proof-of-concept study

artículo científico publicado en 2016

Evaluation of single and combination therapies with tenofovir disoproxil fumarate and emtricitabine in vitro and in a robust mouse model supporting high levels of hepatitis B virus replication

artículo científico publicado en 2012

Jak Inhibitors Modulate Production of Replication-Competent Zika Virus in Human Hofbauer, Trophoblasts, and Neuroblastoma cells

artículo científico

Long-term exposure to AZT, but not d4T, increases endothelial cell oxidative stress and mitochondrial dysfunction

artículo científico publicado en 2008

Quantifying mixed populations of drug-resistant human immunodeficiency virus type 1.

artículo científico publicado en 2005

Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome

artículo científico publicado en 2010

Synthesis and Anti-Hepatitis B Virus and Anti-Hepatitis C Virus Activities of 7-Deazaneplanocin A Analogues in Vitro

artículo científico publicado en 2009

Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl-7-deazapurine nucleosides, their phosphoramidate prodrugs and 5'-triphosphates

artículo científico publicado el 29 de septiembre de 2011

Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogs

artículo científico publicado en 2017

Synthesis and antiviral evaluation of fluorinated acyclo-nucleosides and their phosphoramidates

artículo científico publicado en 2016

Synthesis and antiviral evaluation of novel heteroarylpyrimidines analogs as HBV capsid effectors

artículo científico publicado en 2017

Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector

artículo científico publicado en 2017

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3′-azido-2′,3′-dideoxypurine nucleosides

artículo científico publicado el 30 de mayo de 2011

Toward Elimination of Hepatitis B Virus Using Novel Drugs, Approaches, and Combined Modalities

artículo científico publicado en 2016

Towards HBV curative therapies

artículo científico publicado en 2018

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

artículo científico publicado en 2017

β-D-2'-C-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5'-Triphosphate Forms

artículo científico publicado en 2015