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Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer

artículo científico publicado en 2013

Assessment of a HER2 scoring system for colorectal cancer: results from a validation study

artículo científico

Blockade of EGFR and MEK intercepts heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer

artículo científico publicado en 2014

Clonal evolution and KRAS-MET coamplification during secondary resistance to EGFR-targeted therapy in metastatic colorectal cancer.

artículo científico publicado en 2016

Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.

artículo científico publicado en 2015

Detection of circulating tumor DNA in early- and late-stage human malignancies

artículo científico publicado en 2014

Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial

artículo científico publicado en 2016

Enteric-type adenocarcinoma of the lung harbouring a novel KRAS Q22K mutation with concomitant KRAS polysomy: a case report.

artículo científico publicado en 2015

Erlotinib versus docetaxel as second-line treatment of patients with advanced non-small-cell lung cancer and wild-type EGFR tumours (TAILOR): a randomised controlled trial

artículo científico publicado en 2013

Erratum: Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

scientific article published on 01 July 2015

KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy

artículo científico publicado en 2013

KRAS mutations affect prognosis of non-small-cell lung cancer patients treated with first-line platinum containing chemotherapy

artículo científico publicado en 2015

Multi-Center Evaluation of the Fully Automated PCR-Based Idylla™ KRAS Mutation Assay for Rapid KRAS Mutation Status Determination on Formalin-Fixed Paraffin-Embedded Tissue of Human Colorectal Cancer.

artículo científico publicado en 2016

Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer

artículo científico publicado en 2008

Novel CAD-ALK gene rearrangement is drugable by entrectinib in colorectal cancer

artículo científico publicado en 2015

Pooled Analysis of Clinical Outcome of Patients with Chemorefractory Metastatic Colorectal Cancer Treated within Phase I/II Clinical Studies Based on Individual Biomarkers of Susceptibility: A Single-Institution Experience

artículo científico publicado en 2017

Synergistic antitumor activity of cetuximab and namitecan in human squamous cell carcinoma models relies on cooperative inhibition of EGFR expression and depends on high EGFR gene copy number

artículo científico publicado en 2013

TRKA expression and NTRK1 gene copy number across solid tumours.

artículo científico publicado en 2018

[Genomics in cardiological clinical practice: from the individual response to drug therapy and monogenic cardiovascular disorders]

artículo científico publicado en 2010

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