Lista de obras -

A Population Pharmacokinetic Model Incorporating Saturable Pharmacokinetics and Autoinduction for High Rifampicin Doses

artículo científico publicado en 2017

A Step toward an Optimized Rifampin Dose Completed.

artículo científico publicado en 2015

A dose-ranging trial to optimize the dose of rifampin in the treatment of tuberculosis

artículo científico publicado en 2015

A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP)

artículo científico publicado en 2016

Accelerating the transition of new tuberculosis drug combinations from Phase II to Phase III trials: New technologies and innovative designs

scientific article published on 09 July 2019

Activity of the efflux pump inhibitor SILA 421 against drug-resistant tuberculosis

scholarly article by Sami O. Simons et al published May 2013 in International Journal of Antimicrobial Agents

Antituberculosis drug-induced hepatotoxicity is uncommon in Tanzanian hospitalized pulmonary TB patients

artículo científico publicado en 2010

Antituberculosis drug-induced hepatotoxicity: concise up-to-date review

artículo científico publicado en 2007

Are phylogenetic position, virulence, drug susceptibility and in vivo response to treatment in mycobacteria interrelated?

artículo científico

Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment

artículo científico publicado en 2013

Characterization of Mycobacterium orygis as M. tuberculosis complex subspecies

artículo científico publicado en 2012

Childhood tuberculosis in the Kilimanjaro region: lessons from and for the TB programme

artículo científico publicado en 2010

Clinical experience with the combined use of lopinavir/ritonavir and rifampicin

artículo científico publicado en 2009

Clinical relevance of Mycobacterium chelonae–abscessus group isolation in 95 patients

artículo científico publicado en 2009

Clinical relevance of Mycobacterium szulgai in The Netherlands

artículo científico publicado en 2008

Clinical relevance of nontuberculous Mycobacteria, Oman

artículo científico publicado en 2009

Clofazimine does not lead to significant QT interval prolongation: a multicentre study

Comparative study on genotypic and phenotypic second-line drug resistance testing of Mycobacterium tuberculosis complex isolates

artículo científico publicado en 2010

Conflicting Findings on an Intermediate Dose of Rifampicin for Pulmonary Tuberculosis

artículo científico publicado en 2019

Consequences of noncompliance for therapy efficacy and emergence of resistance in murine tuberculosis caused by the Beijing genotype of Mycobacterium tuberculosis

artículo científico publicado en 2012

Diagnosis and interim treatment outcomes from the first cohort of multidrug-resistant tuberculosis patients in Tanzania

artículo científico publicado en 2013

Direct comparison of Xpert MTB/RIF assay with liquid and solid mycobacterial culture for quantification of early bactericidal activity

artículo científico publicado en 2013

Disseminated Mycobacterium avium subsp. avium infection in a cat, the Netherlands

article by Piet Hein S. de Groot et al published August 2010 in Veterinary Microbiology

Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB.

artículo científico publicado en 2012

Drug susceptibility testing and pharmacokinetics question current treatment regimens in Mycobacterium simiae complex disease

artículo científico publicado en 2011

Drug treatment of pulmonary nontuberculous mycobacterial disease in HIV-negative patients: the evidence

artículo científico

Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients

artículo científico publicado en 2015

Efavirenz, tenofovir and emtricitabine combined with first-line tuberculosis treatment in tuberculosis-HIV-coinfected Tanzanian patients: a pharmacokinetic and safety study

artículo científico publicado en 2012

Effect of diabetes mellitus on TB drug concentrations in Tanzanian patients

artículo científico publicado en 2019

Efficacy and safety of two dosages of cotrimoxazole as preventive treatment for HIV-infected Malawian adults with new smear-positive tuberculosis

article

Electronic monitoring of treatment adherence and validation of alternative adherence measures in tuberculosis patients: a pilot study

artículo científico publicado en 2011

Enhancement of in vitro activity of tuberculosis drugs by addition of thioridazine is not reflected by improved in vivo therapeutic efficacy

artículo científico publicado en 2014

Epidemiology of Mycobacterium bovis disease in humans, The Netherlands, 1993-2007

artículo científico publicado en 2011

Global Clinical Trials for the Treatment of TB with Thioridazine ⬇️

artículo científico publicado el 1 de mayo de 2011

Greater Early Bactericidal Activity at Higher Rifampicin Doses Revealed by Modeling and Clinical Trial Simulations

scientific article published on 01 August 2018

High incidence of adverse events in healthy volunteers receiving rifampicin and adjusted doses of lopinavir/ritonavir tablets

artículo científico publicado en 2008

High-dose rifampicin in tuberculosis: Experiences from a Dutch tuberculosis centre

artículo científico publicado en 2019

High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial

artículo científico publicado en 2016

High-resolution typing by integration of genome sequencing data in a large tuberculosis cluster

artículo científico publicado en 2010

Hydrazine-induced liver toxicity is enhanced by glutathione depletion but is not mediated by oxidative stress in HepG2 cells.

artículo científico publicado en 2009

Hypersensitivity pneumonitis caused by Mycobacterium avium subsp. hominissuis in a hot tub, as proven by IS1245 RFLP and rep-PCR typing

scientific article published in 2012

Immune defects in patients with pulmonary <i>Mycobacterium abscessus</i> disease without cystic fibrosis

artículo científico publicado en 2020

Impact of New American Thoracic Society Diagnostic Criteria on Management of Nontuberculous Mycobacterial Infection

In vitro activity of thioridazine against mycobacteria

In vitro drug susceptibility of 2275 clinical non-tuberculous Mycobacterium isolates of 49 species in The Netherlands

artículo científico publicado en 2009

In vitro synergy between clofazimine and amikacin in treatment of nontuberculous mycobacterial disease

artículo científico publicado en 2012

Innovative Trial Designs Are Practical Solutions for Improving the Treatment of Tuberculosis

artículo científico publicado en 2012

Invasive disease caused by nontuberculous mycobacteria, Tanzania

artículo científico publicado en 2009

Isolation of mycobacteria other than Mycobacterium avium from porcine lymph nodes

artículo científico publicado en 2010

Isoniazid and its toxic metabolite hydrazine induce in vitro pyrazinamide toxicity

artículo científico publicado en 2008

Laboratory diagnosis of pulmonary tuberculosis in TB and HIV endemic settings and the contribution of real time PCR for M. tuberculosis in bronchoalveolar lavage fluid

artículo científico publicado en 2007

Low rate of fluoroquinolone resistance in Mycobacterium tuberculosis isolates from northern Tanzania

artículo científico publicado en 2011

M. tuberculosis genotypic diversity and drug susceptibility pattern in HIV-infected and non-HIV-infected patients in northern Tanzania

artículo científico publicado en 2007

Modifying the multi-arm multi-stage (MAMS) design for use in a phase II tuberculosis trial in sub-Saharan Africa with a time-to-event primary outcome

artículo científico publicado en 2013

Mutations in the regulatory network underlie the recent clonal expansion of a dominant subclone of the Mycobacterium tuberculosis Beijing genotype

artículo científico publicado en 2011

Mycobacterial disease in patients with rheumatic disease

scientific article published on December 2008

Mycobacterium avium complex bacteria remain viable in sputum during storage and refrigeration

scientific article published on 27 June 2018

Mycobacterium heckeshornense infection in an immunocompetent patient and identification by 16S rRNA sequence analysis of culture material and a histopathology tissue specimen

artículo científico publicado en 2004

Mycobacterium mantenii sp. nov., a pathogenic, slowly growing, scotochromogenic species

artículo científico publicado en 2009

Mycobacterium noviomagense sp. nov.; clinical relevance evaluated in 17 patients

artículo científico publicado en 2009

Mycobacterium riyadhense sp. nov., a non-tuberculous species identified as Mycobacterium tuberculosis complex by a commercial line-probe assay

artículo científico publicado en 2009

Mycobacterium sherrisii sp. nov., a slow-growing non-chromogenic species

artículo científico publicado en 2010

Mycobacterium xenopi clinical relevance and determinants, the Netherlands

artículo científico publicado en 2008

Networking in international health: introducing the Federation of European Societies for Tropical Medicine and International Health (FESTMIH).

artículo científico publicado en 2005

New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development

artículo científico publicado en 2008

No human transmission ofMycobacterium malmoensein a perfect storm setting

article

Non-typhoidal salmonella bacteraemia among HIV-infected Malawian adults: high mortality and frequent recrudescence

artículo científico publicado en 2002

Nontuberculous mycobacteria in respiratory tract infections, eastern Asia

artículo científico publicado en 2011

Nontuberculous mycobacteria: clinically relevant

artículo científico publicado en 2010

Nontuberculous mycobacterial pulmonary disease and Aspergillus co-infection: Bonnie and Clyde?

artículo científico publicado en 2019

Nosocomial outbreak of multi-resistant serotype 15A in a centre for chronic pulmonary diseases

Optimization of the rifampin dosage to improve the therapeutic efficacy in tuberculosis treatment using a murine model

artículo científico publicado en 2013

Otomastoiditis caused by Mycobacterium abscessus, The Netherlands

artículo científico publicado en 2010

Outcomes of hypertonic saline inhalation as a treatment modality in nontuberculous mycobacterial pulmonary disease

scientific article published on 11 July 2019

Patient satisfaction with TB care clinical consultations in Kampala: a cross sectional study

artículo científico publicado en 2016

Pharmacokinetics of first-line tuberculosis drugs in Tanzanian patients

artículo científico publicado en 2013

Pharmacological interactions between rifampicin and antiretroviral drugs: challenges and research priorities for resource-limited settings

artículo científico publicado en 2015

Phenotypic Changes on Mycobacterium Tuberculosis-Specific CD4 T Cells as Surrogate Markers for Tuberculosis Treatment Efficacy

scholarly article by Mohamed I M Ahmed et al published 2018 in Frontiers in Immunology

Pneumococcal disease in HIV-infected Malawian adults: acute mortality and long-term survival

artículo científico publicado en 2002

Preferential deletion events in the direct repeat locus of Mycobacterium tuberculosis

artículo científico publicado en 2011

Prevalence of nontuberculous mycobacteria in COPD patients with exacerbations

scholarly article by Wouter Hoefsloot et al published June 2013 in Journal of Infection

Protein binding of rifampicin is not saturated when using high-dose rifampicin

scientific article published on 01 April 2019

Pulmonary Mycobacterium szulgai infection and treatment in a patient receiving anti-tumor necrosis factor therapy.

artículo científico publicado en 2007

Regimens for nontuberculous mycobacterial lung disease lack early bactericidal activity

artículo científico publicado en 2015

Region of difference 1 in nontuberculous Mycobacterium species adds a phylogenetic and taxonomical character

artículo científico publicado en 2009

Resistance mechanisms and drug susceptibility testing of nontuberculous mycobacteria

artículo científico

Rifampicin can be given as flat-dosing instead of weight-band dosing

artículo científico publicado en 2019

Role of rpsA gene sequencing in diagnosis of pyrazinamide resistance

artículo científico publicado en 2013

SILA 421, an inhibitor of efflux pumps of cancer cells, enhances the killing of intracellular extensively drug-resistant tuberculosis (XDR-TB).

artículo científico publicado en 2009

SILA-421 activity in vitro against rifampicin-susceptible and rifampicin-resistant Mycobacterium tuberculosis, and in vivo in a murine tuberculosis model

artículo científico publicado en 2015

SNP/RD typing of Mycobacterium tuberculosis Beijing strains reveals local and worldwide disseminated clonal complexes

artículo científico publicado en 2011

Sale of fluoroquinolones in northern Tanzania: a potential threat for fluoroquinolone use in tuberculosis treatment

artículo científico publicado en 2010

Shorter treatment for multidrug-resistant tuberculosis: the good, the bad and the ugly.

artículo científico publicado en 2016

Subtle immunodeficiencies in nodular-bronchiectatic Mycobacterium avium complex lung disease

artículo científico publicado en 2020

Surveillance of adverse events in the treatment of drug-resistant tuberculosis: A global feasibility study

scientific article published on 03 April 2019

Surveillance of adverse events in the treatment of drug-resistant tuberculosis: first global report

artículo científico publicado en 2019

Synergistic activity of rifampicin and ethambutol against slow-growing nontuberculous mycobacteria is currently of questionable clinical significance

scholarly article by Jakko van Ingen et al published July 2013 in International Journal of Antimicrobial Agents

The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis.

artículo científico publicado en 2018

The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis

artículo científico publicado en 2010

The complexity of the adherence‐response relationship in tuberculosis treatment: why are we still in the dark and how can we get out? ⬇️

artículo científico publicado el 6 de marzo de 2011

The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: an NTM-NET collaborative study

artículo científico publicado en 2013

The impact of repeated NALC/NaOH- decontamination on the performance of Xpert MTB/RIF assay.

artículo científico publicado en 2018

The pharmacokinetics and pharmacodynamics of pulmonary Mycobacterium avium complex disease treatment

artículo científico publicado en 2012

The relationship between Mycobacterium tuberculosis MGIT time to positivity and cfu in sputum samples demonstrates changing bacterial phenotypes potentially reflecting the impact of chemotherapy on critical sub-populations

artículo científico publicado en 2014

The tempo and mode of molecular evolution of Mycobacterium tuberculosis at patient-to-patient scale

artículo científico publicado en 2009

Therapeutic drug monitoring in the treatment of tuberculosis patients ⬇️

artículo científico publicado el 11 de diciembre de 2011

Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!

artículo científico publicado en 2010

Treatable factors associated with severe anaemia in adults admitted to medical wards in Blantyre, Malawi, an area of high HIV seroprevalence

artículo científico publicado en 2005

Treatment and outcome of non-tuberculous mycobacterial pulmonary disease in a predominantly fibro-cavitary disease cohort

artículo científico publicado en 2017

Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis

scientific article published in The Lancet

Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecular Bacterial Load Assay

artículo científico publicado en 2020

Tuberculosis risk factors among tuberculosis patients in Kampala, Uganda: implications for tuberculosis control

artículo científico publicado en 2015

Tuberculosis transmission by patients with smear-negative pulmonary tuberculosis in a large cohort in the Netherlands

artículo científico publicado en 2008

Validation of pncA gene sequencing in combination with the mycobacterial growth indicator tube method to test susceptibility of Mycobacterium tuberculosis to pyrazinamide

artículo científico publicado en 2011

Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study

artículo científico publicado en 2013

Why Do We Use 600 mg of Rifampicin in Tuberculosis Treatment?

artículo científico publicado en 2011

XDR tuberculosis

artículo científico publicado en 2011

Xanthine oxidase inhibition by allopurinol increases in vitro pyrazinamide-induced hepatotoxicity in HepG2 cells

artículo científico publicado en 2010

Lista de obras de

A Population Pharmacokinetic Model Incorporating Saturable Pharmacokinetics and Autoinduction for High Rifampicin Doses

A Step toward an Optimized Rifampin Dose Completed.

A dose-ranging trial to optimize the dose of rifampin in the treatment of tuberculosis

A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP)

Accelerating the transition of new tuberculosis drug combinations from Phase II to Phase III trials: New technologies and innovative designs

Activity of the efflux pump inhibitor SILA 421 against drug-resistant tuberculosis

Antituberculosis drug-induced hepatotoxicity is uncommon in Tanzanian hospitalized pulmonary TB patients

Antituberculosis drug-induced hepatotoxicity: concise up-to-date review

Are phylogenetic position, virulence, drug susceptibility and in vivo response to treatment in mycobacteria interrelated?

Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment

Characterization of Mycobacterium orygis as M. tuberculosis complex subspecies

Childhood tuberculosis in the Kilimanjaro region: lessons from and for the TB programme

Clinical experience with the combined use of lopinavir/ritonavir and rifampicin

Clinical relevance of Mycobacterium chelonae–abscessus group isolation in 95 patients

Clinical relevance of Mycobacterium szulgai in The Netherlands

Clinical relevance of nontuberculous Mycobacteria, Oman

Clofazimine does not lead to significant QT interval prolongation: a multicentre study

Comparative study on genotypic and phenotypic second-line drug resistance testing of Mycobacterium tuberculosis complex isolates

Conflicting Findings on an Intermediate Dose of Rifampicin for Pulmonary Tuberculosis

Consequences of noncompliance for therapy efficacy and emergence of resistance in murine tuberculosis caused by the Beijing genotype of Mycobacterium tuberculosis

Diagnosis and interim treatment outcomes from the first cohort of multidrug-resistant tuberculosis patients in Tanzania

Direct comparison of Xpert MTB/RIF assay with liquid and solid mycobacterial culture for quantification of early bactericidal activity

Disseminated Mycobacterium avium subsp. avium infection in a cat, the Netherlands

Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB.

Drug susceptibility testing and pharmacokinetics question current treatment regimens in Mycobacterium simiae complex disease

Drug treatment of pulmonary nontuberculous mycobacterial disease in HIV-negative patients: the evidence

Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients

Efavirenz, tenofovir and emtricitabine combined with first-line tuberculosis treatment in tuberculosis-HIV-coinfected Tanzanian patients: a pharmacokinetic and safety study

Effect of diabetes mellitus on TB drug concentrations in Tanzanian patients

Efficacy and safety of two dosages of cotrimoxazole as preventive treatment for HIV-infected Malawian adults with new smear-positive tuberculosis

Electronic monitoring of treatment adherence and validation of alternative adherence measures in tuberculosis patients: a pilot study

Enhancement of in vitro activity of tuberculosis drugs by addition of thioridazine is not reflected by improved in vivo therapeutic efficacy

Epidemiology of Mycobacterium bovis disease in humans, The Netherlands, 1993-2007

Global Clinical Trials for the Treatment of TB with Thioridazine ⬇️

Greater Early Bactericidal Activity at Higher Rifampicin Doses Revealed by Modeling and Clinical Trial Simulations

High incidence of adverse events in healthy volunteers receiving rifampicin and adjusted doses of lopinavir/ritonavir tablets

High-dose rifampicin in tuberculosis: Experiences from a Dutch tuberculosis centre

High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial

High-resolution typing by integration of genome sequencing data in a large tuberculosis cluster

Hydrazine-induced liver toxicity is enhanced by glutathione depletion but is not mediated by oxidative stress in HepG2 cells.

Hypersensitivity pneumonitis caused by Mycobacterium avium subsp. hominissuis in a hot tub, as proven by IS1245 RFLP and rep-PCR typing

Immune defects in patients with pulmonary <i>Mycobacterium abscessus</i> disease without cystic fibrosis

Impact of New American Thoracic Society Diagnostic Criteria on Management of Nontuberculous Mycobacterial Infection

In vitro activity of thioridazine against mycobacteria

In vitro drug susceptibility of 2275 clinical non-tuberculous Mycobacterium isolates of 49 species in The Netherlands

In vitro synergy between clofazimine and amikacin in treatment of nontuberculous mycobacterial disease

Innovative Trial Designs Are Practical Solutions for Improving the Treatment of Tuberculosis

Invasive disease caused by nontuberculous mycobacteria, Tanzania

Isolation of mycobacteria other than Mycobacterium avium from porcine lymph nodes

Isoniazid and its toxic metabolite hydrazine induce in vitro pyrazinamide toxicity

Laboratory diagnosis of pulmonary tuberculosis in TB and HIV endemic settings and the contribution of real time PCR for M. tuberculosis in bronchoalveolar lavage fluid

Low rate of fluoroquinolone resistance in Mycobacterium tuberculosis isolates from northern Tanzania

M. tuberculosis genotypic diversity and drug susceptibility pattern in HIV-infected and non-HIV-infected patients in northern Tanzania

Modifying the multi-arm multi-stage (MAMS) design for use in a phase II tuberculosis trial in sub-Saharan Africa with a time-to-event primary outcome

Mutations in the regulatory network underlie the recent clonal expansion of a dominant subclone of the Mycobacterium tuberculosis Beijing genotype

Mycobacterial disease in patients with rheumatic disease

Mycobacterium avium complex bacteria remain viable in sputum during storage and refrigeration

Mycobacterium heckeshornense infection in an immunocompetent patient and identification by 16S rRNA sequence analysis of culture material and a histopathology tissue specimen

Mycobacterium mantenii sp. nov., a pathogenic, slowly growing, scotochromogenic species

Mycobacterium noviomagense sp. nov.; clinical relevance evaluated in 17 patients

Mycobacterium riyadhense sp. nov., a non-tuberculous species identified as Mycobacterium tuberculosis complex by a commercial line-probe assay

Mycobacterium sherrisii sp. nov., a slow-growing non-chromogenic species

Mycobacterium xenopi clinical relevance and determinants, the Netherlands

Networking in international health: introducing the Federation of European Societies for Tropical Medicine and International Health (FESTMIH).

New drugs against tuberculosis: problems, progress, and evaluation of agents in clinical development

No human transmission ofMycobacterium malmoensein a perfect storm setting

Non-typhoidal salmonella bacteraemia among HIV-infected Malawian adults: high mortality and frequent recrudescence

Nontuberculous mycobacteria in respiratory tract infections, eastern Asia

Nontuberculous mycobacteria: clinically relevant

Nontuberculous mycobacterial pulmonary disease and Aspergillus co-infection: Bonnie and Clyde?

Nosocomial outbreak of multi-resistant serotype 15A in a centre for chronic pulmonary diseases

Optimization of the rifampin dosage to improve the therapeutic efficacy in tuberculosis treatment using a murine model

Otomastoiditis caused by Mycobacterium abscessus, The Netherlands

Outcomes of hypertonic saline inhalation as a treatment modality in nontuberculous mycobacterial pulmonary disease

Patient satisfaction with TB care clinical consultations in Kampala: a cross sectional study

Pharmacokinetics of first-line tuberculosis drugs in Tanzanian patients

Pharmacological interactions between rifampicin and antiretroviral drugs: challenges and research priorities for resource-limited settings

Phenotypic Changes on Mycobacterium Tuberculosis-Specific CD4 T Cells as Surrogate Markers for Tuberculosis Treatment Efficacy

Pneumococcal disease in HIV-infected Malawian adults: acute mortality and long-term survival