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A Heptad Repeat in Herpes Simplex Virus 1 gH, Located Downstream of the α-Helix with Attributes of a Fusion Peptide, Is Critical for Virus Entry and Fusion.

artículo científico publicado en 2007

A heptad repeat in herpes simplex virus 1 gH, located downstream of the alpha-helix with attributes of a fusion peptide, is critical for virus entry and fusion

artículo científico publicado en 2005

A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors

artículo científico publicado en 2006

Construction of a fully retargeted herpes simplex virus 1 recombinant capable of entering cells solely via human epidermal growth factor receptor 2.

artículo científico publicado en 2008

Critical residues in the CC' ridge of the human nectin1 receptor V domain enable herpes simplex virus entry into the cell and act synergistically with the downstream region

artículo científico publicado en 2002

Entry of alphaherpesviruses into the cell

Entry of herpes simplex virus mediated by chimeric forms of nectin1 retargeted to endosomes or to lipid rafts occurs through acidic endosomes

artículo científico publicado en 2004

Eradication of glioblastoma by immuno-virotherapy with a retargeted oncolytic HSV in a preclinical model

scientific article published on 12 February 2019

HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses

scholarly article by Laura Menotti published in June 2018

Herpes Simplex Virus Oncolytic Immunovirotherapy: The Blossoming Branch of Multimodal Therapy

scientific article published on 05 November 2020

Inhibition of human tumor growth in mice by an oncolytic herpes simplex virus designed to target solely HER-2-positive cells

scholarly article

Oncolytic herpes virus retargeted to HER-2.

artículo científico publicado en 2009

Optical biosensor analysis in studying herpes simplex virus glycoprotein D binding to target nectin1 receptor

artículo científico publicado en 2003

Preclinical therapy of disseminated HER-2⁺ ovarian and breast carcinomas with a HER-2-retargeted oncolytic herpesvirus.

artículo científico publicado en 2013

Prominent role of the Ig-like V domain in trans-interactions of nectins. Nectin3 and nectin 4 bind to the predicted C-C'-C"-D beta-strands of the nectin1 V domain

artículo científico publicado en 2002

Replication-competent herpes simplex virus retargeted to HER2 as therapy for high-grade glioma

artículo científico publicado en 2012

Rescue, Purification, and Characterization of a Recombinant HSV Expressing a Transgenic Protein

artículo científico publicado en 2020

Rethinking herpes simplex virus: the way to oncolytic agents

artículo científico publicado en 2011

Substitution in the murine nectin1 receptor of a single conserved amino acid at a position distal from the herpes simplex virus gD binding site confers high-affinity binding to gD.

artículo científico publicado en 2002

The herpes simplex virus JMP mutant enters receptor-negative J cells through a novel pathway independent of the known receptors nectin1, HveA, and nectin2.

artículo científico publicado en 2004

The molecular basis of herpesviruses as oncolytic agents

artículo científico publicado en 2012

The multipartite system that mediates entry of herpes simplex virus into the cell

artículo científico publicado en 2007

The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry

artículo científico publicado en 2004

Viral and cellular contributions to herpes simplex virus entry into the cell

artículo científico

oHSV Genome Editing by Means of galK Recombineering

artículo científico publicado en 2020