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Allergic FcεRI- and pseudo-allergic MRGPRX2-triggered mast cell activation routes are independent and inversely regulated by SCF.

artículo científico

An efficient method for gene knock-down by RNA interference in human skin mast cells

artículo científico publicado en 2017

Baseline and stimulated turnover of cell surface c-Kit expression in different types of human mast cells

artículo científico publicado en 2006

IL-33 and MRGPRX2-Triggered Activation of Human Skin Mast Cells-Elimination of Receptor Expression on Chronic Exposure, but Reinforced Degranulation on Acute Priming

scientific article published on 11 April 2019

IL-4 and human skin mast cells revisited: reinforcement of a pro-allergic phenotype upon prolonged exposure

artículo científico publicado en 2016

Integration of the human dermal mast cell into the organotypic co-culture skin model

artículo científico publicado en 2014

Long-term cultured human skin mast cells are suitable for pharmacological studies of anti-allergic drugs due to high responsiveness to FcεRI cross-linking

artículo científico publicado en 2011

MRGPRX2 is negatively targeted by SCF and IL-4 to diminish pseudo-allergic stimulation of skin mast cells in culture

scholarly article by Magda Babina published in August 2018

Mast cell lines HMC-1 and LAD2 in comparison with mature human skin mast cells--drastically reduced levels of tryptase and chymase in mast cell lines

artículo científico publicado en 2010

Mast cell-derived TNF-α and histamine modify IL-6 and IL-8 expression and release from cutaneous tumor cells

artículo científico publicado en 2011

Phenotypic variability in human skin mast cells

artículo científico publicado en 2015

Retinoic Acid Negatively Impacts Proliferation and MCTC Specific Attributes of Human Skin Derived Mast Cells, but Reinforces Allergic Stimulability

artículo científico publicado en 2017

Retinoic acid potentiates inflammatory cytokines in human mast cells: identification of mast cells as prominent constituents of the skin retinoid network

artículo científico publicado en 2015

Skin mast cell phenotypes between two highly divergent cohorts - more pronounced variability within than between groups

artículo científico publicado en 2016

Skin mast cells develop non-synchronized changes in typical lineage characteristics upon culture

Testosterone exerts selective anti-inflammatory effects on human skin mast cells in a cell subset dependent manner

artículo científico publicado en 2012

Yin-Yang of IL-33 in Human Skin Mast Cells: Reduced Degranulation, but Augmented Histamine Synthesis through p38 Activation

artículo científico publicado en 2019