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Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

scientific article published on 08 January 2020

Cancer risks in Lynch syndrome, Lynch-like syndrome, and familial colorectal cancer type X: a prospective cohort study

scientific article published on 24 May 2020

Efficacy of annual colonoscopic surveillance in individuals with hereditary nonpolyposis colorectal cancer

artículo científico publicado en 2009

Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue

artículo científico publicado en 2004

Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility.

artículo científico publicado en 2010

Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium

artículo científico publicado en 2006

Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium

scientific article published on 13 October 2004

No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies

artículo científico publicado en 2018

Spectrum and frequencies of mutations in MSH2 and MLH1 identified in 1,721 German families suspected of hereditary nonpolyposis colorectal cancer

artículo científico publicado en 2005

Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families

article

Value of upper GI endoscopy for gastric cancer surveillance in patients with Lynch syndrome

scientific article published on 15 September 2020

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