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A targeted deletion/insertion in the mouse Pcsk1 locus is associated with homozygous embryo preimplantation lethality, mutant allele preferential transmission and heterozygous female susceptibility to dietary fat.

artículo científico publicado en 2007

An in vitro model maintaining taxon-specific functional activities of the gut microbiome

artículo científico publicado en 2019

Assessing the impact of protein extraction methods for human gut metaproteomics

article

Berberine and its structural analogs have differing effects on functional profiles of individual gut microbiomes

scientific article published on 06 May 2020

Bottom-Up Proteomics (2013-2015): Keeping up in the Era of Systems Biology

artículo científico publicado en 2015

Chemoenzymatic Method for Glycoproteomic N-Glycan Type Quantitation

scientific article published on 20 December 2019

Differential Lysis Approach Enables Selective Extraction of Taxon-Specific Proteins for Gut Metaproteomics

artículo científico publicado en 2020

Evaluating in Vitro Culture Medium of Gut Microbiome with Orthogonal Experimental Design and a Metaproteomics Approach.

artículo científico publicado en 2017

Evaluating live microbiota biobanking using an <i>ex vivo</i> microbiome assay and metaproteomics

artículo científico publicado en 2022

Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.

artículo científico publicado en 2005

Expression of PCSK1 (PC1/3), PCSK2 (PC2) and PCSK3 (furin) in mouse small intestine.

artículo científico publicado en 2008

In Vitro Metabolic Labeling of Intestinal Microbiota for Quantitative Metaproteomics.

artículo científico publicado en 2016

MetaLab: an automated pipeline for metaproteomic data analysis

artículo científico publicado en 2017

MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota

artículo científico publicado en 2016

Metaproteomics reveals associations between microbiome and intestinal extracellular vesicle proteins in pediatric inflammatory bowel disease

artículo científico publicado en 2018

Mice Fed a High-Cholesterol Diet Supplemented with Quercetin-3-Glucoside Show Attenuated Hyperlipidemia and Hyperinsulinemia Associated with Differential Regulation of PCSK9 and LDLR in their Liver and Pancreas.

artículo científico publicado en 2018

Novel loss-of-function PCSK9 variant is associated with low plasma LDL cholesterol in a French-Canadian family and with impaired processing and secretion in cell culture

artículo científico publicado en 2011

Of PCSK9, cholesterol homeostasis and parasitic infections: possible survival benefits of loss-of-function PCSK9 genetic polymorphisms

artículo científico publicado en 2007

PCSK2-null mice exhibit delayed intestinal motility, reduced refeeding response and altered plasma levels of several regulatory peptides.

artículo científico publicado en 2010

PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans

artículo científico publicado en 2008

PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities.

artículo científico publicado en 2009

Peptide-Centric Approaches Provide an Alternative Perspective To Re-Examine Quantitative Proteomic Data.

artículo científico publicado en 2016

Plasma PCSK9 levels are significantly modified by statins and fibrates in humans

artículo científico publicado en 2008

Plasma PCSK9 levels correlate with cholesterol in men but not in women

artículo científico publicado en 2007

RapidAIM: a culture- and metaproteomics-based Rapid Assay of Individual Microbiome responses to drugs

artículo científico publicado en 2020

Studying the Temporal Dynamics of the Gut Microbiota Using Metabolic Stable Isotope Labeling and Metaproteomics

artículo científico publicado en 2020

The enigma of soluble LDLR: could inflammation be the key?

artículo científico publicado en 2020

Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn's disease

artículo científico publicado en 2020

iMetaLab 1.0: a web platform for metaproteomics data analysis

artículo científico publicado en 2018