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739 - A Novel Orally Administered Recombinant Anti-TNF Alpha Fusion Protein for the Treatment of Mild to Moderate Ulcerative Colitis: Results of a Phase 2A Clinical Trial Showing Promising Results

artículo científico publicado en 2018

A Multicenter, Double-Blind, Randomized Safety and Efficacy Study of Two Dose Levels of Taliglucerase Alfa in Pediatric Patients with Gaucher Disease.

scholarly article

A Phase 3, multicenter, open-label, switchover trial to assess the safety and efficacy of taliglucerase alfa, a plant cell-expressed recombinant human glucocerebrosidase, in adult and pediatric patients with Gaucher disease previously treated with i

scientific article published on 18 June 2014

A plant-derived recombinant human glucocerebrosidase enzyme--a preclinical and phase I investigation

artículo científico publicado en 2009

An oral administration of a recombinant anti-TNF fusion protein is biologically active in the gut promoting regulatory T cells: Results of a phase I clinical trial using a novel oral anti-TNF alpha-based therapy

artículo científico publicado en 2017

Enzyme replacement therapy with taliglucerase alfa: 36-month safety and efficacy results in adult patients with Gaucher disease previously treated with imiglucerase

scientific article published on 22 April 2016

Ex vivo transduction of human dermal tissue structures for autologous implantation production and delivery of therapeutic proteins

artículo científico publicado en 2005

Human erythropoietin gene therapy for patients with chronic renal failure

artículo científico publicado en 2005

Improving the accuracy of MRI spleen and liver volume measurements: A phase III Gaucher disease clinical trial setting as a model

artículo científico publicado el 17 de noviembre de 2010

Long-term efficacy and safety results of taliglucerase alfa up to 36 months in adult treatment-naïve patients with Gaucher disease

scientific article published on 19 March 2016

Novel Orally Administered Recombinant Anti-TNF Alpha Fusion Protein for the Treatment of Ulcerative Colitis: Results From a Phase 2a Clinical Trial

artículo científico publicado en 2020

Once every 4 weeks - 2 mg/kg of pegunigalsidase alfa for treating Fabry disease Preliminary results of a phase 3 study

artículo científico publicado en 2019

Pegunigalsidase alfa for the treatment of Fabry disease: Preliminary results from a phase III open label, switch over study from agalsidase alfa

artículo científico publicado en 2019

Pegunigalsidase alfa, a novel PEGylated enzyme replacement therapy for Fabry disease, provides sustained plasma concentrations and favorable pharmacodynamics: A 1-year Phase 1/2 clinical trial

artículo científico publicado en 2019

Pivotal trial with plant cell-expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease

artículo científico publicado en 2011

Preclinical and first-in-human evaluation of PRX-105, a PEGylated, plant-derived, recombinant human acetylcholinesterase-R

artículo científico publicado en 2015

Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system

artículo científico publicado en 2007

Safety and efficacy of two dose levels of taliglucerase alfa in pediatric patients with Gaucher disease

artículo científico publicado en 2014

Zimran A, Brill-Almon E, Chertkoff R, et al. Pivotal trial with plant cell?expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease. Blood. 2011;118(22):.

artículo científico publicado en 2012