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Antiangiogenic and antitumor activity of a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor ZD6474 in a metastatic human pancreatic tumor model

artículo científico publicado en 2007

Clinical development of new drug-radiotherapy combinations ⬇️

artículo científico publicado en 2016

Combining radiotherapy with AZD2171, a potent inhibitor of vascular endothelial growth factor signaling: pathophysiologic effects and therapeutic benefit

artículo científico publicado en 2007

Inhibiting vascular endothelial growth factor receptor-2 signaling reduces tumor burden in the ApcMin/+ mouse model of early intestinal cancer

artículo científico publicado en 2006

Inhibition of Aurora-B kinase activity confers antitumor efficacy in preclinical mouse models of early and advanced gastrointestinal neoplasia

artículo científico publicado en 2012

Inhibition of PARP-1 by olaparib (AZD2281) increases the radiosensitivity of a lung tumor xenograft.

artículo científico publicado en 2011

Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy

artículo científico publicado en 2020

The VEGF receptor tyrosine kinase inhibitor, ZD6474, inhibits angiogenesis and affects microvascular architecture within an orthotopically implanted renal cell carcinoma

artículo científico publicado en 2004

The mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) enhances the radiation responsiveness of lung and colorectal tumor xenografts

artículo científico publicado en 2009

ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: schedule-dependent enhancement of antitumor activity.

artículo científico publicado en 2004

ZD6474, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, inhibits growth of experimental lung metastasis and production of malignant pleural effusions in a non-small cell lung cancer model

artículo científico publicado en 2006

ZD6474--a novel inhibitor of VEGFR and EGFR tyrosine kinase activity

artículo científico publicado en 2005

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