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A Distinct Lung-Interstitium-Resident Memory CD8(+) T Cell Subset Confers Enhanced Protection to Lower Respiratory Tract Infection

artículo científico publicado en 2016

A Novel MCL1 Inhibitor Combined with Venetoclax Rescues Venetoclax-Resistant Acute Myelogenous Leukemia.

artículo científico publicado en 2018

A Phyllodes-like Mammary Tumor in a Breeding Galago (Otolemur garnettii).

artículo científico publicado en 2016

A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus

artículo científico publicado en 2014

A closer look: secondary glaucoma more likely

artículo científico publicado en 2007

A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis

artículo científico publicado en 2011

Acute clearance of human metapneumovirus occurs independently of natural killer cells

artículo científico publicado en 2014

Acute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland function

artículo científico publicado en 2006

Advancing translational research

scientific article published on 01 March 2011

Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner

artículo científico publicado en 2014

An Introduction to Pathology in Biomedical Research: A Mission-Critical Specialty for Reproducibility and Rigor in Translational Research

scientific article published on 01 December 2018

Analysis of the Staphylococcus aureus abscess proteome identifies antimicrobial host proteins and bacterial stress responses at the host-pathogen interface

artículo científico publicado en 2013

Anesthesia and Euthanasia of Brine Shrimp (Artemia franciscana)

scientific article published on 29 November 2018

Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model

artículo científico publicado en 2016

BET inhibition enhances the antileukemic activity of low-dose Venetoclax in acute myeloid leukemia

scientific article published on 04 November 2020

Bacterial sinusitis and otitis media following influenza virus infection in ferrets

artículo científico publicado en 2006

Beyond the H&E: Advanced Technologies for in situ Tissue Biomarker Imaging

artículo científico publicado en 2018

Border Patrol Gone Awry: Lung NKT Cell Activation by Francisella tularensis Exacerbates Tularemia-Like Disease

artículo científico publicado en 2015

Broad-spectrum suppression of bacterial pneumonia by aminoglycoside-propagated Acinetobacter baumannii

artículo científico publicado en 2020

COX Inhibition Increases Alternaria-Induced Pulmonary Group 2 Innate Lymphoid Cell Responses and IL-33 Release in Mice

artículo científico publicado en 2020

Cardiovascular and craniofacial defects in Crk-null mice

artículo científico publicado en 2006

Caspase-7 deficiency protects from endotoxin-induced lymphocyte apoptosis and improves survival.

artículo científico publicado en 2009

Cdc42 promotes host defenses against fatal infection

artículo científico publicado en 2013

Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP)

artículo científico publicado en 2007

Correction to "Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies"

artículo científico publicado en 2020

Cytokine secretion requires phosphatidylcholine synthesis

artículo científico publicado en 2008

Cytokine secretion requires phosphatidylcholine synthesis

Decreased Mdm2 Expression Inhibits Tumor Development and Extends Survival Independent of Arf and Dependent on p53 ⬇️

artículo científico publicado el 28 de septiembre de 2012

Deficiency of gp91phox inhibits allergic airway inflammation

artículo científico publicado en 2013

Delayed marrow infusion in mice enhances hematopoietic and osteopoietic engraftment by facilitating transient expansion of the osteoblastic niche.

artículo científico publicado en 2013

Deregulated Hepatic Metabolism Exacerbates Impaired Testosterone Production in Mrp4-deficient Mice ⬇️

artículo científico publicado el 28 de febrero de 2012

Diminished reovirus capsid stability alters disease pathogenesis and littermate transmission

artículo científico publicado en 2015

Discovering naturally processed antigenic determinants that confer protective T cell immunity

artículo científico publicado en 2013

EWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice

artículo científico publicado en 2007

Effect of hemagglutinin-neuraminidase inhibitors BCX 2798 and BCX 2855 on growth and pathogenicity of Sendai/human parainfluenza type 3 chimera virus in mice

artículo científico publicado en 2009

Effects of Habitat Complexity on Pair-Housed Zebrafish

artículo científico publicado en 2015

Effects of fractionated radiation on the brain vasculature in a murine model: blood-brain barrier permeability, astrocyte proliferation, and ultrastructural changes.

artículo científico publicado en 2006

Efficacy of the novel parainfluenza virus haemagglutinin-neuraminidase inhibitor BCX 2798 in mice - further evaluation

artículo científico publicado en 2009

Evaluation of Mice Undergoing Serial Oral Gavage While Awake or Anesthetized

artículo científico publicado en 2016

Exophthalmos and corneal edema in a young ferret. Diagnosis: glaucoma

artículo científico publicado en 2006

Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia

artículo científico publicado en 2007

Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids

scientific article published on 24 July 2020

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression

artículo científico publicado en 2013

Genomic landscape of a metastatic malignant proliferating tricholemmal tumor and its response to PI3K inhibition

artículo científico publicado en 2019

Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells

artículo científico publicado en 2006

Glucagon-like peptide 1 signaling inhibits allergen-induced lung IL-33 release and reduces group 2 innate lymphoid cell (ILC2) cytokine production in vivo.

artículo científico publicado en 2018

Glucagon-like peptide-1 receptor signaling attenuates RSV-induced type 2 responses and immunopathology

artículo científico publicado en 2018

Glycan Shielding of the Influenza Virus Hemagglutinin Contributes to Immunopathology in Mice ⬇️

artículo científico publicado el 8 de octubre de 2010

Glycan engagement dictates hydrocephalus induction by serotype 1 reovirus

artículo científico publicado en 2015

Haploinsufficiency of the Myc regulator Mtbp extends survival and delays tumor development in aging mice

scientific article published on 30 October 2016

Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons

artículo científico publicado en 2008

Human metapneumovirus virus-like particles induce protective B and T cell responses in a mouse model

artículo científico publicado en 2014

Hyperlipidemic hypersensitivity to lethal microbial inflammation and its reversal by selective targeting of nuclear transport shuttles

artículo científico publicado en 2021

IL-17A induces signal transducers and activators of transcription-6-independent airway mucous cell metaplasia

scientific article published on June 2013

Id2 is dispensable for myc-induced lymphomagenesis

artículo científico publicado en 2004

Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue

artículo científico publicado en 2019

Imaging mass spectrometry for assessing temporal proteomics: analysis of calprotectin in Acinetobacter baumannii pulmonary infection

artículo científico publicado en 2013

Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82 ⬇️

artículo científico publicado el 21 de septiembre de 2011

Immunotherapy with a Combination of Intravenous Immune Globulin and P4 Peptide Rescues Mice from Postinfluenza Pneumococcal Pneumonia ⬇️

artículo científico publicado el 7 de marzo de 2011

Impaired autophagy, defective T cell homeostasis, and a wasting syndrome in mice with a T cell-specific deletion of Vps34.

artículo científico publicado en 2013

Improved Prognosis and Increased Tumor-Infiltrating Lymphocytes in Patients Who Have SCLC With Neurologic Paraneoplastic Syndromes

scientific article published on 12 June 2019

Inactivation of phospholipase D diminishes Acinetobacter baumannii pathogenesis

artículo científico publicado en 2010

Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis

artículo científico publicado en 2010

Influenza enhances susceptibility to natural acquisition of and disease due to Streptococcus pneumoniae in ferrets.

artículo científico publicado en 2010

Influenza virus primes mice for pneumonia from Staphylococcus aureus.

artículo científico publicado en 2011

Loss of mitochondrial protein Fus1 augments host resistance to Acinetobacter baumannii infection

scientific journal article

Loss of the N-linked glycan at residue 173 of human parainfluenza virus type 1 hemagglutinin-neuraminidase exposes a second receptor-binding site.

artículo científico publicado en 2008

Lung CD8+ T Cell Impairment Occurs during Human Metapneumovirus Infection despite Virus-Like Particle Induction of Functional CD8+ T Cells

artículo científico publicado en 2015

MLF1 is a proapoptotic antagonist of HOP complex-mediated survival

artículo científico publicado en 2017

Male mice not alone in research

artículo científico publicado en 2010

MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer

artículo científico publicado en 2015

Mitochondrial protein Fus1/Tusc2 in premature aging and age-related pathologies: critical roles of calcium and energy homeostasis

artículo científico publicado en 2017

Modulating Isoprenoid Biosynthesis Increases Lipooligosaccharides and Restores Acinetobacter baumannii Resistance to Host and Antibiotic Stress

scientific article published on 01 September 2020

Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells

artículo científico publicado en 2019

Multimodal Multiplexed Immunoimaging with Nanostars to Detect Multiple Immunomarkers and Monitor Response to Immunotherapies

scientific article published on 02 January 2020

Multiple Inhibitory Pathways Contribute to Lung CD8+ T Cell Impairment and Protect against Immunopathology during Acute Viral Respiratory Infection

artículo científico publicado en 2016

Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis

artículo científico publicado en 2007

N-linked glycosylation attenuates H3N2 influenza viruses

artículo científico publicado en 2007

Nanoparticle delivery improves the pharmacokinetic properties of cyclic dinucleotide STING agonists to open a therapeutic window for intravenous administration

artículo científico publicado en 2020

Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development

scientific journal article

Oral Azacitidine and Cedazuridine Approximate Parenteral Azacitidine Efficacy in Murine Model

artículo científico publicado en 2020

PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology

artículo científico publicado en 2010

Patched2 modulates tumorigenesis in patched1 heterozygous mice

artículo científico publicado en 2006

Peripheral tolerance can be modified by altering KLF2-regulated Treg migration

scientific article published on 26 July 2016

Pharmacokinetics, Tissue Localization, Toxicity, and Treatment Efficacy in the First Small Animal (Rabbit) Model of Intra-Arterial Chemotherapy for Retinoblastoma

artículo científico publicado en 2018

Preclinical Evaluation of 4-[18F]Fluoroglutamine PET to Assess ASCT2 Expression in Lung Cancer

artículo científico publicado en 2015

Primary Epiphyseal Arteriopathy in a Mouse Model of Steroid-Induced Osteonecrosis ⬇️

artículo científico publicado el 11 de mayo de 2013

Protection from Endotoxin Shock by Selective Targeting of Proinflammatory Signaling to the Nucleus Mediated by Importin Alpha 5

scientific article published on 18 September 2019

RAF265 inhibits the growth of advanced human melanoma tumors

artículo científico publicado en 2012

RAGE-Mediated Suppression of Interleukin-10 Results in Enhanced Mortality in a Murine Model of Acinetobacter baumannii Sepsis

artículo científico publicado en 2017

Rabbit Model of Intra-Arterial Chemotherapy Toxicity Demonstrates Retinopathy and Vasculopathy Related to Drug and Dose, Not Procedure or Approach

article

Rapidly fatal pneumonitis from immunotherapy and concurrent SARS-CoV-2 infection in a patient with newly diagnosed lung cancer

artículo científico publicado en 2020

Recombinant Sendai virus as a novel vaccine candidate for respiratory syncytial virus

artículo científico publicado en 2005

Recombinant Sendai virus expressing the G glycoprotein of respiratory syncytial virus (RSV) elicits immune protection against RSV.

artículo científico publicado en 2004

Residues in the heptad repeat a region of the fusion protein modulate the virulence of Sendai virus in mice

artículo científico publicado en 2009

Respiratory syncytial virus (RSV) fusion protein expressed by recombinant Sendai virus elicits B-cell and T-cell responses in cotton rats and confers protection against RSV subtypes A and B

artículo científico publicado en 2007

Respiratory syncytial virus infection activates IL-13-producing group 2 innate lymphoid cells through thymic stromal lymphopoietin

artículo científico publicado en 2016

Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication

artículo científico publicado en 2015

SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice

artículo científico publicado en 2007

STAT1 Represses Cytokine-Producing Group 2 and Group 3 Innate Lymphoid Cells during Viral Infection

artículo científico publicado en 2017

STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge

artículo científico publicado en 2014

Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity

scientific article published on 11 May 2008

Selective roles for antiapoptotic MCL-1 during granulocyte development and macrophage effector function

artículo científico publicado en 2008

Sendai virus recombinant vaccine expressing a secreted, unconstrained respiratory syncytial virus fusion protein protects against RSV in cotton rats

artículo científico publicado en 2014

Seroprevalence of seasonal and pandemic influenza A viruses in domestic cats ⬇️

artículo científico publicado el 28 de septiembre de 2010

Staphylococcus xylosus Cystitis and Struvite Urolithiasis in Nude Mice Implanted with Sustained-release Estrogen Pellets

artículo científico publicado en 2018

Substrain-specific differences in survival and osteonecrosis incidence in a mouse model ⬇️

artículo científico publicado el 1 de diciembre de 2012

Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles.

artículo científico publicado en 2017

TSLP and IL-33 reciprocally promote each other's lung protein expression and ILC2 receptor expression to enhance innate type-2 airway inflammation

scientific article published on 23 January 2020

Targeting SLC1a5-mediated glutamine dependence in non-small cell lung cancer

artículo científico publicado en 2015

Testosterone Attenuates Group 2 Innate Lymphoid Cell-Mediated Airway Inflammation

artículo científico publicado en 2017

The Innate Immune Protein S100A9 Protects from T-Helper Cell Type 2-mediated Allergic Airway Inflammation

scientific article published on 01 October 2019

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis

artículo científico publicado en 2010

The centrosomal, putative tumor suppressor protein TACC2 is dispensable for normal development, and deficiency does not lead to cancer

artículo científico publicado en 2004

The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation

artículo científico publicado en 2016

The immune profile associated with acute allergic asthma accelerates clearance of influenza virus

artículo científico publicado en 2014

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

artículo científico publicado en 2007

The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1

artículo científico publicado en 2009

The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesis

artículo científico publicado en 2005

The novel parainfluenza virus hemagglutinin-neuraminidase inhibitor BCX 2798 prevents lethal synergism between a paramyxovirus and Streptococcus pneumoniae

artículo científico publicado en 2005

The plasticity of regulatory T cell function

artículo científico publicado en 2011

The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development

scientific journal article

The α2β1 integrin is a metastasis suppressor in mouse models and human cancer ⬇️

artículo científico publicado el 6 de diciembre de 2010

Toll-Like Receptor 9 Contributes to Defense against Acinetobacter baumannii Infection.

artículo científico publicado en 2015

Training mouse pathologists: 15 years of workshops on the pathology of mouse models of human disease.

artículo científico publicado en 2017

Training mouse pathologists: 16th annual workshop on the pathology of mouse models of human disease

artículo científico publicado en 2018

Transgenic mice with pancellular enhanced green fluorescent protein expression in primitive hematopoietic cells and all blood cell progeny.

artículo científico publicado en 2005

Transplantable marrow osteoprogenitors engraft in discrete saturable sites in the marrow microenvironment

artículo científico publicado en 2008

Transplanted murine long-term repopulating hematopoietic cells can differentiate to osteoblasts in the marrow stem cell niche

artículo científico publicado en 2013

Transporter-mediated protection against thiopurine-induced hematopoietic toxicity

artículo científico publicado en 2008

Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenza

artículo científico publicado en 2009

Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis ⬇️

artículo científico publicado el 6 de junio de 2012

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

artículo científico publicado en 2005

Viral acute lower respiratory infections impair CD8+ T cells through PD-1

artículo científico publicado en 2012

p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network.

artículo científico publicado en 2016

p73 Is Required for Ovarian Follicle Development and Regulates a Gene Network Involved in Cell-to-Cell Adhesion

El receptor 2 tipo Toll media la inmunopatología fatal en ratones durante el tratamiento de la neumonía neumocócica secundaria después de la gripe ⬇️

artículo científico publicado el 7 de septiembre de 2011

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