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A chitinase-like protein in the lung and circulation of patients with severe asthma

artículo científico publicado en 2007

A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo

artículo científico publicado en 2011

A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo

artículo científico publicado en 2008

Alterations in Fas (CD 95/Apo-1) and Fas ligand (CD178) expression in acute promyelocytic leukemia during treatment with ATRA.

artículo científico publicado en 2004

An audience with...Peter Kiener

artículo científico publicado en 2009

Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors

artículo científico publicado en 2009

B-cell depletion in vitro and in vivo with an afucosylated anti-CD19 antibody

artículo científico publicado en 2010

C-3 Amido-indole cannabinoid receptor modulators

artículo científico publicado en 2002

Cell Type-Specific Recognition of Human Metapneumoviruses (HMPVs) by Retinoic Acid-Inducible Gene I (RIG-I) and TLR7 and Viral Interference of RIG-I Ligand Recognition by HMPV-B1 Phosphoprotein

artículo científico publicado en 2010

Comparative effects of two neutralizing anti-respiratory syncytial virus (RSV) monoclonal antibodies in the RSV murine model: time versus potency

artículo científico publicado en 2005

Correction: Type I Interferon: Potential Therapeutic Target for Psoriasis?

artículo científico publicado en 2009

Development of Potential Pharmacodynamic and Diagnostic Markers for Anti-IFN-α Monoclonal Antibody Trials in Systemic Lupus Erythematosus

artículo científico publicado en 2009

Development of motavizumab, an ultra-potent antibody for the prevention of respiratory syncytial virus infection in the upper and lower respiratory tract

artículo científico publicado en 2007

Differential EphA2 epitope display on normal versus malignant cells

artículo científico publicado en 2003

Differentiation of promyelocytic leukaemia: alterations in Fas (CD95/Apo-1) and Fas ligand (CD178) expression

artículo científico publicado en 2002

Direct targeting of alphavbeta3 integrin on tumor cells with a monoclonal antibody, Abegrin

artículo científico publicado en 2006

EphA2 expression is associated with aggressive features in ovarian carcinoma

artículo científico publicado en 2004

Genomic-based high throughput screening identifies small molecules that differentially inhibit the antiviral and immunomodulatory effects of IFN-alpha

artículo científico publicado en 2008

IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways

artículo científico publicado en 2010

Identification of antibody neutralization epitopes on the fusion protein of human metapneumovirus

artículo científico publicado en 2008

Identification of purine inhibitors of phosphodiesterase 7 (PDE7).

artículo científico publicado en 2004

In vivo administration of 15-deoxyspergulin inhibits antigen-presenting cell stimulation of T cells and NF-kappaB activation

artículo científico publicado en 2002

Increasing the affinity of a human IgG1 for the neonatal Fc receptor: biological consequences.

artículo científico publicado en 2002

Isolation and characterization of monoclonal antibodies which neutralize human metapneumovirus in vitro and in vivo

artículo científico publicado en 2006

Macrophage impairment underlies airway occlusion in primary respiratory syncytial virus bronchiolitis

artículo científico publicado en 2008

Monoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides.

artículo científico publicado en 2013

Motavizumab, a neutralizing anti-Respiratory Syncytial Virus (Rsv) monoclonal antibody significantly modifies the local and systemic cytokine responses induced by Rsv in the mouse model

artículo científico publicado en 2007

Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus

artículo científico publicado en 2009

PC cell-derived growth factor expression in prostatic intraepithelial neoplasia and prostatic adenocarcinoma

artículo científico publicado en 2004

Potent control of tumor growth by CEA/CD3-bispecific single-chain antibody constructs that are not competitively inhibited by soluble CEA.

artículo científico publicado en 2009

Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties

artículo científico publicado el 22 de mayo de 2003

Respiratory syncytial virus (RSV) RNA loads in peripheral blood correlates with disease severity in mice

artículo científico publicado en 2010

Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma

artículo científico publicado en 2010

Selective targeting and potent control of tumor growth using an EphA2/CD3-Bispecific single-chain antibody construct

artículo científico publicado en 2007

Serum levels of CD137 ligand and CD178 are prognostic factors for progression of myelodysplastic syndrome

artículo científico publicado en 2004

Simultaneous targeting of TNF and Ang2 with a novel bispecific antibody enhances efficacy in an in vivo model of arthritis

artículo científico publicado en 2012

Strictly target cell-dependent activation of T cells by bispecific single-chain antibody constructs of the BiTE class

artículo científico publicado en 2007

Targeting the junction of CɛmX and ɛ-migis for the specific depletion of mIgE-expressing B cells

artículo científico publicado en 2012

Type I interferon-inducible gene expression in blood is present and reflects disease activity in dermatomyositis and polymyositis.

artículo científico publicado en 2007

Type I interferon: potential therapeutic target for psoriasis?

artículo científico publicado en 2008

Ultra-potent antibodies against respiratory syncytial virus: effects of binding kinetics and binding valence on viral neutralization

artículo científico publicado en 2005

YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages

artículo científico publicado en 2008