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(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology

artículo científico publicado en 2016

Adiponectin is required for maintaining normal body temperature in a cold environment.

artículo científico publicado en 2017

Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels

artículo científico publicado en 2019

CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide

artículo científico publicado en 2017

CRMP2 and voltage-gated ion channels: potential roles in neuropathic pain

Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet

artículo científico publicado en 2017

Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light

scientific article published on 02 May 2019

Dissecting the role of the CRMP2-neurofibromin complex on pain behaviors.

artículo científico publicado en 2017

Erratum to ‛Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light': The Journal of Pain 20 (2019) 1293-1306

scientific article published on 01 December 2019

Long-lasting antinociceptive effects of green light in acute and chronic pain in rats.

artículo científico publicado en 2017

Mining the Nav1.7 interactome: Opportunities for chronic pain therapeutics

artículo científico publicado en 2019

Studies on CRMP2 SUMOylation-deficient transgenic mice identify sex-specific NaV1.7 regulation in the pathogenesis of chronic neuropathic pain

scientific article published on 11 June 2020

Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential.

artículo científico publicado en 2016

Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy

scientific article published on 01 July 2019

Tetramethylpyrazine Reduces Epileptogenesis Progression in Electrical Kindling Models by Modulating Hippocampal Excitatory Neurotransmission

scientific article published on 06 December 2019

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