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(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity

artículo científico publicado en 2020

5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein

scientific article published on 19 March 2020

Agreement between an in-house replication competent and a reference replication defective recombinant virus assay for measuring phenotypic resistance to HIV-1 protease, reverse transcriptase, and integrase inhibitors.

artículo científico publicado en 2017

Comparable In Vitro Activities of Second-Generation HIV-1 Integrase Strand Transfer Inhibitors (INSTIs) on HIV-1 Clinical Isolates with INSTI Resistance Mutations

artículo científico publicado en 2019

Comparative analysis of different cell systems for Zika virus (ZIKV) propagation and evaluation of anti-ZIKV compounds in vitro

artículo científico publicado en 2017

DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins

artículo científico publicado en 2020

Development of a Cell-Based Immunodetection Assay for Simultaneous Screening of Antiviral Compounds Inhibiting Zika and Dengue Virus Replication

artículo científico publicado en 2020

Development of an internally controlled quantitative PCR to measure total cell-associated HIV-1 DNA in blood

artículo científico publicado en 2017

Evaluation of sofosbuvir activity and resistance profile against West Nile virus in vitro

scientific article published on 10 January 2020

Identification of novel 2-benzoxazolinone derivatives with specific inhibitory activity against the HIV-1 nucleocapsid protein

artículo científico publicado en 2017

In vitro cross-resistance to doravirine in a panel of HIV-1 clones harbouring multiple NNRTI resistance mutations

scientific article published on 24 September 2020

In vitro susceptibility to fostemsavir is not affected by long-term exposure to antiviral therapy in MDR HIV-1-infected patients

artículo científico publicado en 2020

Maraviroc as a potential HIV-1 latency-reversing agent in cell line models and ex vivo CD4 T cells

scientific article published on 13 October 2020

Performance of Geno2Pheno[coreceptor] to infer coreceptor use in human immunodeficiency virus type 1 (HIV-1) subtype A

article

Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains.

artículo científico publicado en 2017

Synthesis and Evaluation of Bifunctional Aminothiazoles as Antiretrovirals Targeting the HIV-1 Nucleocapsid Protein

article

The HIV-1 integrase E157Q polymorphism per se does not alter susceptibility to raltegravir and dolutegravir in vitro

artículo científico publicado en 2017

The HIV-1 reverse transcriptase E138A natural polymorphism decreases the genetic barrier to resistance to etravirine in vitro

article