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A Targeted Multiplexed MALDI MS Assay Platform using Affinity-Bead Assisted Mass Spectrometry (Affi-BAMS) for Monitoring Brain and CSF Biomarkers

artículo científico publicado en 2020

A first-in-human dose-escalation study of the oral proteasome inhibitor oprozomib in patients with advanced solid tumors

artículo científico publicado en 2016

Alzheimer's Disease-Like Neurodegeneration in Porphyromonas gingivalis Infected Neurons with Persistent Expression of Active Gingipains

artículo científico publicado en 2020

An ab Initio structural model of a nucleoside permease predicts functionally important residues.

artículo científico publicado en 2009

Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide-based substrates and covalent inhibitors

scientific article published on 24 June 2019

Clinical activity of carfilzomib correlates with inhibition of multiple proteasome subunits: application of a novel pharmacodynamic assay

artículo científico publicado en 2016

Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit

artículo científico publicado en 2017

Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion ⬇️

artículo científico publicado en 2006

Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393.

artículo científico publicado en 2003

Gingipains Identified in Alzheimer's Disease Brains Differentially Fragment ApoE Proteins

artículo científico publicado en 2021

Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum

artículo científico publicado en 2008

Immunoproteasome functions explained by divergence in cleavage specificity and regulation.

artículo científico publicado en 2017

Molecular Mechanisms of Bortezomib Resistant Adenocarcinoma Cells ⬇️

artículo científico publicado el 22 de diciembre de 2011

Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events ⬇️

artículo científico publicado el 1 de mayo de 2011

Novel aza peptide inhibitors and active-site probes of papain-family cysteine proteases

artículo científico publicado en 2006

Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii

artículo científico publicado en 2006

Point mutations within the LdNT2 nucleoside transporter gene from Leishmania donovani confer drug resistance and transport deficiency

artículo científico publicado en 2006

Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.

artículo científico publicado en 2019

Ricolinostat (ACY-1215) induced inhibition of aggresome formation accelerates carfilzomib-induced multiple myeloma cell death

artículo científico publicado en 2015

Second-site suppression of a nonfunctional mutation within the Leishmania donovani inosine-guanosine transporter

artículo científico publicado en 2004

Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388

scientific article published on 01 February 2020

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