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Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential.

artículo científico publicado en 2015

Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo.

artículo científico publicado en 2018

Cotargeting signaling pathways driving survival and cell cycle circumvents resistance to Kit inhibitors in leukemia

artículo científico publicado el 20 de marzo de 2012

Erythropoietin down-regulates stem cell factor receptor (Kit) expression in the leukemic proerythroblast: role of Lyn kinase

artículo científico publicado en 2009

Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene

scientific article published on 22 September 2018

Extracellular vesicles released by polycyclic aromatic hydrocarbons-treated hepatocytes trigger oxidative stress in recipient hepatocytes by delivering iron

artículo científico publicado en 2020

Ezrin is a target for oncogenic Kit mutants in murine erythroleukemia.

artículo científico publicado en 2008

MEHP/ethanol co-exposure favors the death of steatotic hepatocytes, possibly through CYP4A and ADH involvement

artículo científico publicado en 2020

Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide

scientific article published on 27 September 2018

Membrane Remodeling as a Key Player of the Hepatotoxicity Induced by Co-Exposure to Benzo[a]pyrene and Ethanol of Obese Zebrafish Larvae.

artículo científico publicado en 2018

Multiple functional domains of the oncoproteins Spi-1/PU.1 and TLS are involved in their opposite splicing effects in erythroleukemic cells

artículo científico publicado en 2004

Oncogenic kit triggers Shp2/Erk1/2 pathway to down-regulate the pro-apoptotic protein Bim and to promote apoptosis resistance in leukemic cells

artículo científico publicado en 2012

Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor

scientific article published on 31 July 2019

Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.

artículo científico publicado en 2017

Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis

artículo científico publicado en 2017

Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia

artículo científico publicado en 2012

Spi-1/PU.1 oncoprotein affects splicing decisions in a promoter binding-dependent manner

scientific article published on 11 May 2006

The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival.

artículo científico publicado en 2016