Lista de obras -

Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma

artículo científico publicado en 2015

Antitumor effect of parathyroid hormone-related protein neutralizing antibody in human renal cell carcinoma in vitro and in vivo

artículo científico publicado en 2005

Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging ⬇️

artículo científico publicado el 20 de octubre de 2011

Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.

artículo científico publicado en 2016

Detecting the Potential Pharmacological Synergy of Drug Combination by Viability Assays In Vitro

artículo científico publicado en 2018

Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.

artículo científico publicado en 2017

Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality

artículo científico publicado en 2013

Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.

artículo científico publicado en 2009

Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276).

artículo científico publicado en 2017

Glycolytic metabolism of pathogenic T cells enables early detection of GvHD by 13C-MRI

artículo científico publicado en 2020

Hyperpolarized [1-13C]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect

artículo científico publicado en 2018

Increasing reactive oxygen species as a therapeutic approach to treat hereditary leiomyomatosis and renal cell carcinoma ⬇️

artículo científico publicado el 27 de octubre de 2010

Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration

artículo científico publicado en 2015

Met and the microenvironment: new insights for ovarian cancer metastasis

artículo científico publicado en 2011

Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma

artículo científico publicado en 2013

Metabolism and oxidative stress response pathways in kidney cancer: a tale of chance and necessity

artículo científico publicado en 2015

Metformin targets Mitochondrial Glycerophosphate Dehydrogenase (mGPDH) to control Rate of Oxidative Phosphorylation and growth of thyroid cancer in vitro and in vivo.

artículo científico publicado en 2018

Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity

artículo científico publicado en 2014

Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism

artículo científico publicado en 2012

Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis

artículo científico publicado en 2013

New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of disease

artículo científico publicado en 2015

Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments

artículo científico publicado en 2020

Ovarian cancer: emerging molecular-targeted therapies

artículo científico publicado en 2012

Parathyroid hormone-related protein in human renal cell carcinoma

artículo científico publicado en 2005

Parathyroid hormone-related protein induces cell survival in human renal cell carcinoma through the PI3K Akt pathway: evidence for a critical role for integrin-linked kinase and nuclear factor kappa B.

artículo científico publicado en 2007

Plasma HSP90α and liver cancer: a potential biomarker?

artículo científico publicado en 2017

Preclinical efficacy of dual mTORC1/2 inhibitor AZD8055 in renal cell carcinoma harboring a TFE3 gene fusion

scientific article published on 13 September 2019

Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc

scientific article published on 05 December 2019

Protein kinase D inhibitor CRT0066101 suppresses bladder cancer growth in vitro and xenografts via blockade of the cell cycle at G2/M.

artículo científico publicado en 2017

Role of the RNA-binding protein HuR in human renal cell carcinoma

artículo científico publicado en 2010

SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery

artículo científico publicado en 2016

SnapShot: Renal Cell Carcinoma

artículo científico publicado en 2016

Synthesis of a stable and orally bioavailable englerin analogue

artículo científico publicado en 2016

Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer

artículo científico publicado en 2014

Targeting HIF2α translation with Tempol in VHL-deficient clear cell renal cell carcinoma

artículo científico publicado en 2012

Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma

artículo científico publicado en 2013

Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers.

artículo científico publicado en 2018

Targeting the nuclear factor-kappaB rescue pathway has promising future in human renal cell carcinoma therapy

artículo científico publicado en 2007

The HSP90 inhibitor ganetespib synergizes with the MET kinase inhibitor crizotinib in both crizotinib-sensitive and -resistant MET-driven tumor models

artículo científico publicado en 2013

The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels

artículo científico publicado en 2011

The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy

artículo científico publicado en 2006

Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent

artículo científico publicado en 2015

UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer

artículo científico publicado en 2010

Uncoupling tumor-stroma interactions in breast cancer patients

artículo científico publicado en 2017

von Hippel-Lindau tumor suppressor gene-dependent mRNA stabilization of the survival factor parathyroid hormone-related protein in human renal cell carcinoma by the RNA-binding protein HuR.

artículo científico publicado en 2008

Lista de obras de

Alternative splicing of the cell fate determinant Numb in hepatocellular carcinoma

Antitumor effect of parathyroid hormone-related protein neutralizing antibody in human renal cell carcinoma in vitro and in vivo

Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging ⬇️

Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.

Detecting the Potential Pharmacological Synergy of Drug Combination by Viability Assays In Vitro

Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.

Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality

Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.

Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276).

Glycolytic metabolism of pathogenic T cells enables early detection of GvHD by 13C-MRI

Hyperpolarized [1-13C]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer In Vivo Predicts Efficacy of Targeting the Warburg Effect

Increasing reactive oxygen species as a therapeutic approach to treat hereditary leiomyomatosis and renal cell carcinoma ⬇️

Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration

Met and the microenvironment: new insights for ovarian cancer metastasis

Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma

Metabolism and oxidative stress response pathways in kidney cancer: a tale of chance and necessity

Metformin targets Mitochondrial Glycerophosphate Dehydrogenase (mGPDH) to control Rate of Oxidative Phosphorylation and growth of thyroid cancer in vitro and in vivo.

Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity

Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism

Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis

New strategies in renal cell carcinoma: targeting the genetic and metabolic basis of disease

Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments

Ovarian cancer: emerging molecular-targeted therapies

Parathyroid hormone-related protein in human renal cell carcinoma

Parathyroid hormone-related protein induces cell survival in human renal cell carcinoma through the PI3K Akt pathway: evidence for a critical role for integrin-linked kinase and nuclear factor kappa B.

Plasma HSP90α and liver cancer: a potential biomarker?

Preclinical efficacy of dual mTORC1/2 inhibitor AZD8055 in renal cell carcinoma harboring a TFE3 gene fusion

Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc

Protein kinase D inhibitor CRT0066101 suppresses bladder cancer growth in vitro and xenografts via blockade of the cell cycle at G2/M.

Role of the RNA-binding protein HuR in human renal cell carcinoma

SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery

SnapShot: Renal Cell Carcinoma

Synthesis of a stable and orally bioavailable englerin analogue

Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer

Targeting HIF2α translation with Tempol in VHL-deficient clear cell renal cell carcinoma

Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma

Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers.

Targeting the nuclear factor-kappaB rescue pathway has promising future in human renal cell carcinoma therapy

The HSP90 inhibitor ganetespib synergizes with the MET kinase inhibitor crizotinib in both crizotinib-sensitive and -resistant MET-driven tumor models

The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels

The phosphoinositide 3-kinase/Akt pathway: a new target in human renal cell carcinoma therapy

Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent

UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer

Uncoupling tumor-stroma interactions in breast cancer patients

von Hippel-Lindau tumor suppressor gene-dependent mRNA stabilization of the survival factor parathyroid hormone-related protein in human renal cell carcinoma by the RNA-binding protein HuR.