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Anticonvulsant active inhibitor of GABA transporter subtype 1, tiagabine, with activity in mouse models of anxiety, pain and depression

artículo científico publicado en 2014

Antidepressant-like effects of scopolamine in mice are enhanced by the group II mGlu receptor antagonist LY341495.

artículo científico publicado en 2016

Comparison of pro-amnesic efficacy of scopolamine, biperiden, and phencyclidine by using passive avoidance task in CD-1 mice.

artículo científico publicado en 2017

Culinary–medicinal mushrooms: a review of organic compounds and bioelements with antioxidant activity

Development of an in-vivo active reversible butyrylcholinesterase inhibitor.

artículo científico publicado en 2016

Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity

artículo científico publicado en 2021

Effect of pregabalin on contextual memory deficits and inflammatory state-related protein expression in streptozotocin-induced diabetic mice.

artículo científico publicado en 2016

Effect of pregabalin on fear-based conditioned avoidance learning and spatial learning in a mouse model of scopolamine-induced amnesia

artículo científico publicado en 2016

Impact of dams' diet on the levels of magnesium and zinc in the incisors of offspring rats

artículo científico publicado en 2022

Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice

artículo científico publicado en 2019

Novel, highly potent and in vivo active inhibitor of GABA transporter subtype 1 with anticonvulsant, anxiolytic, antidepressant and antinociceptive properties

artículo científico publicado en 2016

Phencyclidine and Scopolamine for Modeling Amnesia in Rodents: Direct Comparison with the Use of Barnes Maze Test and Contextual Fear Conditioning Test in Mice

artículo científico publicado en 2018

Potential role of selected antiepileptics used in neuropathic pain as human GABA transporter isoform 1 (GAT1) inhibitors-Molecular docking and pharmacodynamic studies

artículo científico publicado en 2016

Studies on the Activity of Selected Highly Lipophilic Compounds toward hGAT1 Inhibition. Part II

artículo científico publicado en 2018

Synthesis and anticonvulsant activities of novel 2-(cyclopentylmethylene)hydrazinyl-1,3-thiazoles in mouse models of seizures

artículo científico publicado en 2016

Synthesis, biological evaluation and structure-activity relationship of new GABA uptake inhibitors, derivatives of 4-aminobutanamides.

artículo científico publicado en 2014

The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity

artículo científico publicado en 2017

The anxiolytic-like activity of a novel N-cycloalkyl-N-benzoylpiperazine derivative

artículo científico

The effect of GABA transporter 1 (GAT1) inhibitor, tiagabine, on scopolamine-induced memory impairments in mice.

artículo científico publicado en 2015

The potential antidepressant action and adverse effects profile of scopolamine co-administered with the mGlu7 receptor allosteric agonist AMN082 in mice

scientific article published on 23 August 2018

The role of melatonin, neurokinin, neurotrophic tyrosine kinase and glucocorticoid receptors in antidepressant-like effect

artículo científico publicado en 2017

The role of serotonergic, adrenergic and dopaminergic receptors in antidepressant-like effect

artículo científico publicado en 2015

Yerba Mate as a Source of Elements and Bioactive Compounds with Antioxidant Activity

artículo científico publicado en 2022